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31 Terms
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feasible
* recruits target population strategically * priorities measurable outcomes
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interesting:
attracts attention of readers
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novel:
* provides different findings * improves flaws of existing studies * not doing a study that has been done multiple times before
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ethical:
guarantees safety and reversible side effects
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relevant:
* generates new knowledge * stimulates further research
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Null:
p= 0.05 or above 95% confident that your result you got are based off of the variable that you changed, not for, external circumstances
\ a statement of no difference
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case-series:
* observational * no cause/effect/randomization * all receive treatment * ex: drug trials
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cross-sectional:
* observational * defined population at one time ( present) * helps determine what to study next ( 1st step to cohort) * ex: diabetes study ( defined group)
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case-control:
* observational * outcome is already known * compare subject with disease and wot none * look into past * ex: exposed ( normal) unexposed (cripple) now future of them together
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cohort:
* observational * no cause/effect * no randomization * ex: female nurse who smokes vs one who doesn’t * look into future
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RCT simple:
* 20 subjects randomly in cold immersion * 20 subjects random in none * compare performance
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RCT blocked:
group 1 and 2 get mixed into 2 cohorts together, then one cohort does the experimental treatment
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RCT stratified:
female and males get mixed together, then one group does the experimental treatment
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RCT blind:
* single: patient * double: patient and physician * triple: patient, physician, and investigator
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single RCT:
* require experimental arm (receive treatment) and comparative arm (receive standard test)
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multiple arm:
* allows multiple treatments to be assessed at the same time
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cross over RCT:
* strongest * increases control, removing confounding variables as each subject is serving as their own control * only used if subject an return to baseline between interventions and the subjects status can remain stable throughout the study
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single factors pre/post RCT:
* gold standard * both groups get pre and post measurements * effect of cold immersion on agility performance
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subject single factor:
* used when unethical to with hold a standard treatment when comparing a new treatment * comparative and experimental
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Selection bias:
* Participants in the experiment and control groups differ substantially and cant be compared * Ex: subjects choose their group they want to be in * How to avoid: randomize the experiment
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Maturation effect:
* Time can influence the dependant variable * Ex: growing older, stronger, wiser, and more experienced * How to avoid: have a control group
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Attrition bias:
* Subjects drop out of the study once they started it * How to avoid: randomize the subjects so they cant choose the group they're in, recruit many, minimize # of trials
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testing/order/learning effect:
* The pre-test affects the results of the post-test * Subjects may gotten use to the test bc its repetitive * How to avoid: randomize the order of events
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Instrumentation effect:
* If there is a change in how the dependant variable is being measured during the study * How to avoid: use same everything for each subject, practice before trials
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expectancy/confirmation bias:
* Researchers bias towards an expected result may lead to interpretation of results desired versus what date shows * How to avoid: utilize placebos (fakes) when able
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Social interaction:
* Interaction between subjects from different groups influences the outcome * How to avoid: make sure groups don't interact
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History:
* Unanticipated event change the conditions of the study which may influence the outcome * How to avoid: difficult, recruit more subjects for precaution, have controlled environment
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testing:
participation in pre-test influences the outcome of the IV
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sampling bias:
participants of the study differ substantially from the general population
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hawthorne effect:
* Participants change their behavior because they know they are benign studied or observed thus affecting generalizability * Difficult to eliminate because it is human nature
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funnel:
* factos influencing creatine in brain * effect of creatine supplements * etc * etc
\ next part explains the first part so no questions need to be asked