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Aphthous lesions
Lichen planus
Oral Hairy Leukoplakia
Tonsilith
Vocal chord polyp
Torus
What are the mucosal disorders?
Aphthous Lesions
-Pathogenesis not clear (“Cankersore)
FH, stress, late bedtimes contribute
-most common oral lesion
-Non-keratinized mucosa is the only place this occurs
-Painful
-7-10 day duration
Recurrent Aphthous Stomatitis (RAS)
-Reduced salivary peroxidase
-Associated with increased salivary levels of interleukin-2 and cortisol
-Often a sentinel event for ulcerative colitis relapse
Lichen Planus
-Skin and mucosal inflammatory auto-immune disease
Oral mucosa has white streaks on it.
-Oral manifestations are most common, and usually precede skin lesions if it becomes severe
-Three oral manifestations:
Wickens stria (most common, painless)
Erosive (Painful)
Bullous (painful)
Oral Hairy Leukoplakia (OHL)
Etiology: Epstein Bar virus
Demographic: Immunocompromised, often found in HIV/AIDS
-Careful history
-Refer for biopsy
Vocal Chord Lesions
Nodule:
Trauma/overuse
Usually bilateral
Occasional hoarseness
Polyp:
Often associated with smoking
Hoarseness, dysphonia
Malignant transformation risk
Cyst:
Mucous retention
Sebaceous
Altered voice quality possible
Candidiasis (Thrush)
Cause: Candida Albicans (fungus)
Opportunistic infection
Alteration of normal oral flora balance
Antibiotics
Immune suppression
Topical steroids
Seeding by dentures
Treatment:
Topical antifungals (Nystatin, Myconizole)
Median Rhomboid Glossitis
-Deep candidal infection of central tongue
-Erythematous, smooth, firm
Treatment:
Systemic antifungal (Diflucan)
Tonsilitis
Pharyngitis
Laryngitis
Epiglottitis
What are the different pathologies that lead to a “sore throat”
Acute Tonsillitis
-60-70% viral, 30-40% bacterial (most common: group A strep.)
Signs/Symptoms:
Rapid onset, Sore throat/fever
Tonsillar enlargement
Dysphagia
Painful cervical lymphadenopathy
Centor Criteria (likelihood of GpA strep infection)
Tonsillar exudate
Painful neck nodes
Hx of fever,
no cough.
ages 5-15
DX:
Rapid step test, throat culture if test is negative and suspicion is high
Treatment:
Viral: pain relief, salt water gargles, steroids?
Bacterial: Above plus antibiotics, steroids?
if chronic (>5/yr)…
Adults: surgery
Children: Medical therapy or surgery
Peritonsillar Abscess
-Complication of acute, or acute exacerbation of chronic tonsillitis
Impending medical emergency
Treatment:
Surgical incision and drainage
Pharyngitis
-Supraglottal, nasopharyngeal inflammation
-non-specific clinical sign (classic “sore throat”_
Etiology: Viral cold, strep throat, post nasal rhinorrhea, Mono, Severe xerostomia.
Dx:
Thorough history/physical exam
Consider rapid strep or Throat culture
Treatment:
Treat underlying disease if isolated
Treat symptoms.
Laryngitis
-Inflammation of the larynx (voice box)
Acute:
< 3 weeks, Viral URI
Trauma (coughing, overuse)
Chronic:
>3 weeks
Smoking, allergies, acid reflux
Rheumatoid arthritis, TB, Sarcoidosis
S/S:
hoarseness, fever, cough, pain,
“lump in my throat”
Dysphagia
concerning:
Stridor
Hx of radiation therapy
Epiglottis
-Rapid onset swelling/edema of the epiglottis
-Causes:
H. Flu type B
Strep.
Thermal injury/Chemical injury (e.g. firefighters)
Signs/symptoms:
Drooling, difficulty swallowing
Strider, dyspnea
Fowar head posturing
Cyanosis
Treatment:
MEDICAL EMERGENCY
Oxygen, Hospitalization
Immediate airway management
Need an endotracheal cricoid tube, typically cannot intubate.
Antibiotics/steroids
Herpes Simplex
Prodromal symptoms
Vesicles, open wounds
Yellow cicatrix (scab)
-Can occur on both keratinized/non-keratinized tissue (primarily on the lips)
-Virus may remain dormant in neural fibers after healing
-Recurrence with trauma, stress, and sun exposure.
Treatment:
Topical Acyclovir
Herpes Stomatitis
Diagnosis:
Clinical
Signs/Symptoms
Fever, Halitosis
Refusal to eat/drink (pain)
Cervical lymphadenopathy
Multiple intra/extraoral eruptions of painful ulcers. (widesread)
Differential:
Coxacki viral infection (hand/foot/mouth)
Aphthous stomatitis
Candida albicans
SJS.
Treatment:
Oral or parenteral Acyclovir
Acute Necrotizing Ulcerative Gingivitis (ANUG)
-Unique form of periodontal disease
Rapid onset, necrosis of interdental gingiva
Pain, halitosis, bleeding.
Risk factors:
Malnutrition, Immunocompromised (HIV/AIDs)
Stress, poor oral hygiene
-suspect odontogenic etiology
-Suspect airway compromise
For Oropharyngeal space infections ALWAYS»>>
Ludwig’s Angina
-Bilateral sublingual and submandibular space infections.
Treatment:
I&D
Antibiotics
Retropharyngeal abscess
In children….
1-4 y/o
Spread from other ear/nose/throat primary infections
Airway compromise (untreated)
Treatment:
antibiotics
Rare need for surgical intervention
In adults….
Often spread of other space infections
Often odontogenic
Polymicrobial
Danger space #4
Treatment:
Surgical intervention and antibiotics
Major Salivary gland infections
-Viral infection of the parotid salivary gland (mumps)
Rare, highly infectious
Children: self-limiting.
Adults: complications more frequent
Testes, breasts, ovaries, pancreas, meninges, decreased fertility, rarely → sterilization (males).
Bacterial causes (occur due to reduced flow of saliva)
Sialolithiasis
Mucous plug
Post-radiation, drug-induced
Xerostomia
Sjogren’s disease
Ductal trauma/scarring.
-Infections of the minor salivary glands are exceedingly rare.
Mucocele
-A fluid-filled cyst that forms in the oral mucosa (typically the lips)
Subtle/obvious swelling
Asymmetry
Non-specific pain
Facial/tongue paralysis (cranial nerve exam)
Non-healing ulcers
Habits (alcohol, tobacco, etc..)
HPV vaccine hx
Unusual pigmentation
What are the general principles to take into account when determining if a lesion could be cancerous?
Squamous Cell Carcinoma
-95% of oral malignancies
Oral: Vast majority are environmental
Pharyngeal: HPV
Internal Derangements
Intra-articular disorders
Myofascial disorders
Muscles/ligaments
What are the two categories for TMJ disorders?
Internal Derangements
Characteristics:
Pain is specific to preauricular area
There is, or used to be “popping” or “clicking” on jaw movement. this may be episodic
Almost always unilateral
Often deviation of midline on wide opening
Possible hx of trauma/FH
Myofascial Disorders
Characteristics:
Pain is described as non-localized and episodic
some degree of spasm of one or more masticatory muscles
Stress implications (usually manifested in unconscious clenching of teeth)
Often but not necessarily bilateral
Pain with mandibular function and often at rest
May/may not be associated with joint noise