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What is the main thing that happens in translation
The nucleotide sequence of the mRNA is used to determine the amino acid sequence of a polypeptide
What is the asic thing that happens in transcription
Base sequence of a gene is copied into the complementary base sequence of a molecule mRNA
Where does transcription take place?
In the nucleus
What is the role of the dna helicase in transcription
It breaks hydrogen bonds between polypeptide
What happens after the hydrogen bonds are broken
Complementary rna nucleotides move into place and form hydrogen bonds with exposed bases on nucleotides on one of the dna strands
What does the rna polymerase do?
Joins the RNA nucleotide by forming phosphodiester bonds
What are the different strands
The base sequence of mRNA is the same as the SENSE STRAND But instead of thymine it is replaced with uracil
The mRNA complementary to the other and the one which has formed hydrogen bonds with is called the TEMPLATE STRAND
What happens when the mRNA has been synthesised
The RNA polymerase detaches from the DNA
DNA GOES back to normal double helix stricture
MRNA leaves nucleus via the nuclear Pores
What is tRNA
Transfer RNA
ON ONE Side it has a place for a specific amino acid to bind to
On the other side it has specific anti codons.
Each tRNA has specific a.a that it binds to and specific anticodons
Wwhat does the mRNA fist do
mRNA leaves nucleus via nuclear pore
It attaches to ribosome throug RRNA on ribosome
What does he TRNA do
It is in the cytoplasm
It attaches to their specific a.a
The tRNA bring the a.a attached to them to the mRNA in the ribosome
What happens when the tRNA arrives at the ribosome
The anti codons of the tRNA are complemtary to the codons of the mRNA and so they bind together
How many tRNA can come at a time
2
What happens when 2 trna have arrived at the ribosome and attached to the mRNA codons
A peptide bonds forms between 2 a.a (catalysed by rRNA )
The first tRNA then leaves because the a.a is attached to the 2nd tRNA
What happens after the a.a is bonded bbby peptide bond
Continues process until stop codon is reached on mRNA
The a.a chain is complete and forms final polypeptide
What are the differences in components with both process
Translation
mRNA + tRNA + rRNA
Transcription
DNA + RNA polymerase
What is the difference in template
Trans caption
DNA is the template
Translation
Template is MRNA
What is the difference in end product
Transcription
DNA turns into RNA
Transcription
RNA into protein
What is the difference in location?
Transcription
Nucleus
Translation
Ribosome / cytoplasm
What is the difference in polymerase
Transcription uses rna polymerase
Translation
The enzyme used is ribosome
What are the similarities
Both involve the conversion of one type of genetic material into another
Both use dna helicase
Both form hydrogen bonds
What s a key difference in what moves over what
In transcription the polymerase moves over the template strand of dna
In translation the ribosome tRNA complex moves the mRNA strand