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How many pharyngeal clefts are there, and which one contributes to definitive structures?
Four pairs of pharyngeal clefts
Only the first cleft contributes to permanent structures
What does the first pharyngeal cleft form?
External auditory meatus (lined by ectoderm)
What happens to the 2nd, 3rd, and 4th clefts?
Overgrown by the proliferating 2nd pharyngeal arch
Forms a temporary cervical sinus, which usually disappears
What is a branchial fistula?
Abnormal canal connecting pharynx or skin due to failure of fusion of 2nd arch with epicardial ridge
Can be external, internal, or both
What is a lateral cervical cyst?
Remnant of the cervical sinus
Located along the anterior border of the sternocleidomastoid muscle