Blood Donation / Blood Units

Identify the deferral period:

• Anemics

• Hemophiliacs

Permanent

Identify the deferral period:

• Received human-derived growth hormone, tissue transplant or bovine insulin

Permanent deferral

Identify the deferral period:

• Tegison drug

Permanent

Identify the deferral period:

• Travel to areas endemic to Malaria

1 year

Identify the deferral period:

• Malaria after treatment and recovery

3 years

Identify the deferral period:

• Resident/immigrant where Malaria is endemic

3 years

Identify the deferral period:

• Soriatane drug

3 years

Identify the deferral period:

• After HB Ig

1 year

Identify the deferral period:

• Rabies vaccine

1 year

Identify the deferral period:

• After treatment for Syphilis or Gonorrhea

1 year

Identify the deferral period:

• Needle stick injury

1 year

Identify the deferral period:

• Avodart drug

6 months

Identify the deferral period:

• Rubella vaccine

1 month

Identify the deferral period:

• Rubeola vaccine

2 weeks

Vaccines that defer a donor for 2 weeks

• Salk Oral polio

• MM without the R

• Yellow fever

Identify the deferral period:

• Aspirin

3 days

Identify the deferral period:

• MMR together

8 weeks

Identify the deferral period:

• First trimester or Second trimester abortion / miscarriage

No deferral

Autologous Hemoglobin requirement

11g/dL

Allogeneic Hemoglobin requirement for Males and Females

Male: 13g/dL

Female: 12.5g/dL

Systolic and Diastolic requirement for Allogeneic dononation

Systolic: 90-180 mmHg

Diastolic: 50-100 mmHg

mL of anticoagulant for 450mL and 500m blood bags

450mL = 63mL

500mL = 70mL

For the aseptic technique, the venipuncture site is scrubbed at least _ in all directions

4cm

1 SDP is equivalent to how many RDP units

6-8 units

Common sedimenting agent for Leukapheresis

HES (Hydroxyethyl starch)

HCT needed for Allogeneic donors

Male: 39%

Female: 38%

Each unit of SDP increases PLT count by _

20,000-60,000 /uL

Each unit of RDP increases PLT count by _

5,000-10,000/ uL

Expiration date of washed PLT conc.

4 hours

Pooled products have an expiry date of how many hours

4 hrs

Expiry for thawed cryoprecipitate

6 hrs

The process of removing the AB from the serum

Absorption

Cellano is associated with what BGS and what size?

Kell; small k

1 unit of pRBC/Whole blood increases HCT and Hmg by

HCT: 3-5%

Hmg: 1g/dL

Donath-Landsteiner AB is AKA

Autoanti-P

PNH is associated with what BGS

DAF

Anti-leukocyte ABs cause what problems?

• Febrile non-hemolytic

• TRALI

Irradiated RBCs inactivate what cells?

T-cells

Blood component for GVHD

Irradiated RBCs

FFP is made within how many hours

8 hrs

Universal blood donor for plasma/FFP

AB

Ig associated with HDFN

IgG

TRUE OR FALSE: Bacteremia is grounds for deferral for autologous donation

TRUE

PIGPA stands for _

Pyruvate Inosine Glucose Phosphate Adenine

Drugs associated with collecting WBCs to pull the granulocytes from the marginal pool

• Prednisone

• Dexamethasone

What deactivates AHG if procedure is not done properly

Residual px serum

Expiry of blood units without Adenine

21 days

Expiry of blood units (in general) with Adenine

35 days

Whole blood should increase Hmg and HCT by how much

Hmg: 1g/dL

HCT: 3%

Expiration limit of frozen RBCs

10 years

Purpose for freezing RBCs

• Autologous units

• Storage for rare blood units

Deglycerolized RBCs are washed how many times

4x

Irradiated RBCs expiry

28 days or original expiry

1 unit of SDP should increase PLT by

30,000 - 60,000 /uL

note: RDP = 5,000 - 10,000 /uL

1 unit of RDP should increase PLT by

5,000 - 10,000 /uL

note: SDP = 30,000 - 60,000 /uL

Between SDP and RDP, which is prepared from whole blood?

RDP

FFP must be prepared within _

8 hrs

Expiry of FPP stored in -18C and -65C

-18 C = 1 year

-65 C = 7 years

Temp to thaw FFP

4C

Blood component to give for FXIII deficiency

Cryoprecipitate

Residual leukocytes in leukoreduced RBCs

< 5.00 × 10^6 / L

% retained in leukoreduced RBCs

85%

w/ residual leukocytes being < 5.00 × 10^6 /L

Blood component to give to minimize febrile / allergic rxns

Leukoreduced RBCs

Cause of Febrile Non-hemolytic reaction

Anti-leukocyte ABs of recipient

Cause of TRALI

Donor WBC ABs

Cause of TACO

Volume overload secondary to rapid, high volume

A febrile transfusion rxn is defined as rise in temperature of _

1 C or greater