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a&p & infection prevention
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What 3 elements must be present for an infection to spread in a hospital setting?
Source/reservoir for pathogens
route of transmission for the pathogen
susceptible host
3 modes of transmission for pathogens
Contact (direct & indirect) (most common)
droplet (travels <= 3ft in air)
airborne (droplet nuclei, particles are <=5 micrometers)
These are classified based on particle size!
What does OSHA stand for & what do they do?
Occupational Safety & Health Administration
Makes sure everything is up to standard
What does CDC stand for?
Centers for Disease Control & Prevention
What do standard precautions include? What does it also mean?
Standard precautions are precautions for every patient every time! It’s the simplest level of infection control
Includes…
hand hygiene
gloves
mouth, eye protection, face shields
respiratory protection (ex. mask)
gowns
patient care equipment (can get contaminated since it’s with the patient)
occupational health & bloodborne pathogens
patient placement
Levels for disinfection & sterilization (3 levels)
Lowest level: cleaning
1st step in equipment processing
removes dirt & organic material
Next level: disinfection
Destroys vegetative form of all pathogens except bacterial spores
Can involve chemical or physical methods
Pasteurization is the most common method
Chemical disinfection entails applying chemical solutions to contaminated equipment/surfaces & the equipment must be immersed in solution for set period of time
Top level: sterilization
destroys ALL microorgs
Can be physically or chemically approached
Most common & easiest method is autoclaving (steam sterilization)
Surveillance for hospital acquired infections (device related) (know CLABSI, CAUTI, VAPs, & VAE)
Device-related infections
Central line-associated blood stream infections (CLABSI)
Catheter-associated urinary tract infection (CAUTI)
ventilator associated pneumonia (VAPs)
VAP surveillance definition has significant limitations
Surveillance is performed to look for ventilator-associated events (VAE)
Ventilator-Associated Events (know the 3 tiers: VAC, IVAC, & PVAP)
Broken down into 3 tiers:
Ventilator-associated condition (VAC)
identified with high PEEP or daily minimum FiO2 for 2 days or longer
Infection-related ventilator-associated complication (IVAC)
identified thru high temp or WBC & new antibiotics have been started & administered for at least 4 days
Possible VAP (PVAP)
identified if IVAC identified & positive culture results meet specific threshold values
or they have purulent secretions & positive culture results that don’t meet specific threshold values
Aerosol medications (know SVN, MDI, & DPI)
aerosolized epinephrine introduced as treatment for asthma
1940s-1950s- introduced bronchodilators
SVN- small volume nebulizer
MDI- metered dose inhaler
DPI- dry powdered inhaler
Upper airway vs Lower airway anatomy
Upper airway
nose
mouth
pharynx
epiglottis
top of trachea
Lower airway
bottom of trachea
bronchi
bronchioles
alveoli
capillaries
functions of upper airway
warms incoming air to body temp
filters air
pure by the time it gets to the lungs
humidifies
100% humidity
cellular make up of the airway
made of ciliated pseudostratified columnar epithelium
cilia helps move allergens & foreign stuff out of the body
where does gas exchange occur?
in the alveoli
alveolar gas concentration (just know what’s involved, not the %)
nitrogen
oxygen
CO2
water
concentration of oxygen in the atmosphere
21%
macrophages
attack TB
Consumes stuff (ex. debris, bacteria, dust, etc.)
muscles of respiration (the main one & the inspiratory & expiratory accessory muscles)
(hint: the expiratory muscles are all abdomen related)
Diaphragm (moves down during inhalation & up during exhalation)
Inspiratory Accessory
scalene
sternocleidomastoid
pectoralis major
trapezius
Expiratory Accessory
rectus abdominis
External oblique
internal oblique
transversus abdominis
accessory muscle use for breathing (inspiration)
If these are used to breathe, something is wrong & it’s an emergency!! It should mainly be the diaphragm you use to breathe.
Scalene
inspiratory muscle
extends from cervical vertebrae to 1st & 2nd
Sternocleidomastoid
on side of neck
elevates the sternum
increases AP diameter of chest
pectoralis major
from clavicle to sternum to upper part of humerus
elevates chest
increases AP diameter
trapezius
triangular, bilateral upper portion of back
rotates scapula
elevates rib cage (inhalation)
accessory muscles of expiration
rectus absominis
raises intraabdominal pressure by pushing diaphragm into thoracic cage
compresses abdominal contents
external oblique
compresses abdominal contents
pushes diaphragm into thoracic cage during exhalation
internal oblique
depress the thorax & assist in respiration
pushes diaphragm in thoracic cage (exhalation)
transversus abdominis
the body’s natural corset
constricts abdominal contents
active breathing vs quiet breathing
active breathing- while doing anything (ex. walking)
quiet breathing- while doing nothing (ex. sitting, sleeping)
perfusion vs ventilation
perfusion- flow of blood to alveolar capillaries
ventilation- the flow of air in & out of alveoli
all low-flow, non-invasive devices require…
the patient to be spontaneously breathing
SPO2 range for a COPD patient vs. a non-COPD patient
COPD patient: 88-92% bc you don’t want to knock out their hypoxic drive
non-COPD patient: 93% or higher
when to use humidifiers
3L or more for a long period of time. Don’t use with nebulizer
nasal cannula
FIO2: 24-44%
Delivers 1-6 L/min (low flow)
high flow (green tube) = 6-15 L/min
most procedures start with this
simple mask
FIO2: 35-50%
Delivers 6-12 L/min
must be at least 6L to prevent rebreathing CO2
not used often, just with labor & delivery & outpatient
venturi mask
FIO2: 24-60%
Delivers 4-12 L/min
bigger hole in adapter = lower FIO2 (due to more exposure to the room’s FIO2)
usually for COPD patients
Non-rebreather mask
FIO2: 60-100%
Delivers 6-15 L/min
bag valve mask (BVM)
switch to this when the patient is NOT SPONTANEOUSLY BREATHING
Non-invasive with mask. Becomes invasive when mask is removed
order of devices (depending on severity)
nasal cannula → venturi mask → non-breather → BVM
flow rate (L/min) & FIO2
Starts with 0L/min & 21%
1 L/min has FIO2 of 0.24, then increases by 4% with each liter (ex. 2 L/min has FIO2 of 0.28)
heart valves
aortic valve
pulmonary valve
mitral valve
tricuspid valve
pericardium
outer fibrous layer that surrounds the heart
pericarditis
inflammation of pericardium
layers of the heart wall (outer to inner)
Outer: epicardium
Middle: myocardium (muscle)
Inner: endocardium
chambers of the heart
Top: left & right atria
Bottom: left & right ventricles
systole vs. diastole
systole= cardiac contraction. valves open, allowing ventricular ejection into arteries (pulmonary artery & aorta)
diastole= valves close preventing backflow of blood into ventricles
murmur= valves not closing properly
Left coronary artery (LCA)
positioned underneath aortic semilunar valves
LCA branches into
left anterior descending (LAD): courses between L&R ventricles
Circumflex: courses around L side of heart between L. atrium & L. ventricle
Provides blood to areas like L. atrium & ventricle, majority of interventricular septum, etc.
Right coronary artery (RCA)
RCA proceeds around the right side of heart between R. atrium & R. ventricle
provides blood to these areas
Myocardial Ischemia vs. Myocardial Infarction (MI)
Myocardial Ischemia
partial obstruction of coronary artery
dec. oxygen supply to tissue
AKA Angina Pectoris
Myocardial infarction
complete obstruction of coronary artery
causes death of heart tissue
Conductivity vs. Contractility
Conductivity- spreads impulses quickly
Contractility- contracting in response to electrical impulse
systemic vasculature (know where it begins & ends, each vena cava, & what 3 components make it up)
begins with aorta on L. ventricle & ends on R. atrium
systemic venous blood returns to R. atrium via…
Superior vena cava (SVC)- drains upper extremities & head
Inferior vena cava (IVC) drains lower body
Made of 3 components:
arterial system
capillary system
venous system
PVR
pulmonary vascular resistance
LAP
left atrial pressure of wedge pressure
CO
cardiac output= total amount of blood pumped by heart per minute
CO= heart rate (HR) x stroke volume (SV)
mmHg
milimeters of mercury. Used to determine blood pressure
sphygmomanometer
tool used to measure blood pressure
Frank-Starling’s Law
The greater the stretch, the stronger the contraction
EF
ejection fraction (EF) = SV/EDV
normal respiratory rate
12-20 breaths per minute
normal heart rate
60-100bpm
normal blood pressure
120/60 mmHg
brady- vs tachy-
brady- low/below average.
ex. bradypnea (low beathing)
tachy- high/above average
ex. tachycardia (high heart rate)
adventitious breath sounds
abnormal breath sounds
abnormal breath sounds (5 types)
wheezing- anywhere. Sounds like “whistling” & sounds worse during expiration. Can include COPD, asthma, & airway obstruction
rhonchi- in bronchi (larger airway). “Course crackles.” Can generally be cleared with a cough
rales- in “tails” (ends on side). “Fine crackles.” Sounds like fire crackling with popping sounds
stridor- high pitch sound by neck. Can be heard without stethoscope. Upper airway. Sounds like loud whistling
pleural rub- can be found anywhere on lungs in the cavity between lung & bone. Can be inflammation on pleura. Sounds like creaking boat on dock. Sounds the same on inspiration & expiration, so it’s symmetrical
ABCs
Airway, Breathing, Circulation
pattern to use stethoscope
upper, mid, lower, & diamond on both sides