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exergonic
Releases energy
Happens spontaneously
Example: breaking down sugar
∆G < 0 → a reaction is spontaneous or doesn’t require input of energy to occur
Catabolic
Breaks large molecules into smaller ones
Often releases energy
Example: digesting food
∆G > 0→ a reaction requires energy input to occur
Are usually exergonic
Anabolic
Builds larger molecules from smaller ones
Needs energy input
Example: building muscles
Most anabolic reactions are endergonic
endergonic
Requires energy
Not spontaneous
Example: photosynthesis
First law of thermodynamics
energy cannot be created or destroyed, but can be transferred or transformed
2nd law of thermodynamics
when energy is transformed or transferred, some amount can f energy is lost as heat
potential energy
energy in an object that is NOT moving
Chemical energy
the potential energy stored in chemical bonds
Kinetic energy
energy in an object that IS moving
Thermal energy
the kinetic energy of molecules / small particles
Activation energy
small amount of energy needed to start a chemical reaction
Enzymes
proteins that speed up reactions
Have a specific shape with an active site
Induced fit = enzyme slightly changes shape to fit substrate
Enzymes lower activation energy, making reactions faster and easier
Active site
a pocket on the enzyme—> spot where the enzyme grabs onto the molecule it works on
Substrate
the molecule the enzyme works on —> fits into enzymes active site
allosteric enzymes
can be turned off or on by other molecules
Competitive inhibition
Inhibitor competes with substrate for active site
Blocks substrate from binding
Noncompetitive inhibition
Inhibitor binds elsewhere on enzyme
Changes enzyme’s shape → substrate can’t fit
Normal bindings
if the substrate and it’s enzyme are both present, they will bind together at the active site
Allosteric inhibitor
when it binds, this will stabilize the inactive form of the enzyme
Feedback inhibition
when the end produce of a series of reactions inhibits the first enzyme, shutting down that pathway
Cell uses enzymes to make a product
Too much product builds up
Product “feeds back” and binds to an early enzyme
Enzyme shape changes → pathway stops ✅ Saves energy!
Cellular respiration equation
Glucose + oxygen → carbon dioxide + water + ATP
C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O + ATP
The Gradual Harvesting Of Energy from Glucose:
Glycolysis
Pyruvate oxidation
Citric acid cycle
Oxidative phosphorylation
majority of ATP is made where?
Oxidative phosphorylation
What causes fermentation
When no oxygen is available
Photosynthesis equation
Carbon dioxide + water + sunlight → Glucose + oxygen
6CO₂ + 6H₂O + light → C₆H₁₂O₆ + 6O₂
Light dependent reaction
Location: Thylakoid
Needs sunlight
Water split → O₂ released
Makes ATP + NADPH
Calvin Cycle
Location: Stroma
Uses ATP + NADPH
Fixes CO₂ → builds glucose
Input: CO2
Output: G3P (sugar), NADP+, ATP, phosphate ion
Stages of Calvin Cycle
Carbon Fixation – CO₂ joins RuBP
Reduction – ATP/NADPH → G3P
Regeneration – G3P → RuBP
Describe the interphases
Interphase:
G1: Cell grows
S: DNA is copied
G2: Final checks and prep
Mitotic (M) Phase:
Mitosis → nucleus divides
Cytokinesis → cytoplasm splits
Stages of Mitosis
Prophase
Prometaphase
Metaphase
Anaphase
Telophase
Cytokinesis
Prophase
Chromosomes condense, spindle forms
Prometaphase
Nuclear envelope breaks, spindles attach
Metaphase
Chromosomes line up
Anaphase
Sister chromatids pulled apart
Telophase
Nuclear membranes reform
Cytokinesis
Two cells form
G0 Phase
If a cell doesn’t get right signals to proceed into S Phase, it goes into G0 phase
Non growth phase
Apoptosis
Programmed cell death
Chromatin
Loose, tangled DNA
Chromosomes
Coiled DNA (more visible when dividing)
Sister chromatids
Identical copies joined together of a single chromosome
Homologous chromosomes
One from mom, one from dad – similar but not identical
Mitosis
Only one round
Produces 2 identical daughter cells
Start from diploid cell, end with 2 diploid clones
Meiosis
2 sounds: Meiosis I and Meiosis II
produces 4 genetically unique daughter cells Start
Start from diploid cell, end with 4 haploid gametes
Describe each phase of Meiosis
Meiosis I: homologous chromosomes separated into 2 haploid cells
Prophase:
Metaphase
Meiosis II: sister chromatids in the 2 haploid cells are separated and the end results is 4 haploid cells
Prophase II
Metaphase II : sister chromatids are not identical like at the start of Meiosis I
Anaphase II: sister chromatids are separate by breaking of centromere
Telophase II : 4 genetically unique daughter cells are produced