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Fluid Mosaic Model
Double layer of phospholipids w/ embedded proteins
Within the phospholipid bilayer are Polar Heads and Non-Polar Tails
Peripheral Proteins
Attached to inner or outer membrane surface
Intrinsic/Integral Proteins
Embedded IN the membrane
Some move ions or molecules across the membrane
Some attach the membrane to the cytoskeleton
Cholesterol
Embedded in the interior of the membrane
Makes the membrane less permeable to water-soluble substances
Add rigidity
Glycocalyx (Cell coat)
Glycolipids and Glycoproteins on surface of plasma membrane
“Fingerprint” of the cell
Cell membrane
Site for receptors containing glycocalyx
Selectively permeable
Maintains homeostasis
Types of Passive Transport
Simple Diffusion
Facilitated Diffusion
Osmosis
Simple Diffusion
Movement of molecules from areas of high to low concentration
Move until equilibrium is reached
No energy required
Facilitated Diffusion
Diffuse from high to low concentration using a carrier protein
NECESSARY for large molecules and some that are not lipid soluble
Temporarily binds with a carrier protein in the plasma membrane and transported to low concentration
Osmosis
Diffusion of water across a selectively permeable membrane from high to low
No energy required
Types of Osmosis
Isotonic
Hypertonic
Hypotonic
Isotonic
Same concentration of solutes outside and inside
Hypertonic
Shriveling
Solute concentration is higher outside than inside
Water moves OUT of the cell
Low salt outside
Hypotonic
Swelling
Solute concentration is higher inside than outside
Water moves into the cell
High salt outside
Types of active transport
Filtration
Endocytosis
Exocytosis
Filtration
Molecules are forced across selectively permeable membranes by hydrostatic or blood pressure
Endocytosis
Bulk movement of materials across plasma membrane into the cell
3 forms of Endocytosis
Pinocytosis
Phagocytosis
Receptor-Mediated Endocytosis
Pinocytosis
“Cell drinking”
Uptake of small droplets of extracellular fluid
small portion of plasma membrane becomes invaginated, surrounds droplets, seals itself, and forms a vesicle (Like snake.io)
Phagocytosis
“Cell eating”
Uptake of large solid particles
Recepter-Mediated Endocytosis (w.i.p)
A receptor on the membrane recognizes a molecule outside the cell and binds with it, resulting in an indentation and forms a vesicle
Exocytosis
Secretory vesicle fuses w/ plasma membrane and releases contents out of the cell
This process adds new membrane material and replaces plasma membrane material lost during endocytosis (Cycle)