CYP450 toxicologie
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17 Terms
1
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substraten CYP1A2
- cafeïne
- theofylline
- tricyclische antidepressiva
- warfarine
- antipsychotica
2
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inhibitoren CYP1A2
- fluvoxamine
- erythromycine
- ciprofloxacine
- contraceptiva
3
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inductoren CYP1A2
- carbamazepine
- fenobarbital
- fenytoïne
- primidon
- rifampicine
- roken
4
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substraten CYP2C9
ibuprofen
fenytoïne
warfarine
fenobarbital
5
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inhibitoren CYP2C9
- amiodarone
- miconazol
- fluconazol
- voriconazol
6
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inductoren CYP2C9
- rifampicine (PXR)
- fenobarbital (CAR)
- fenytoïne
- carbamazepine
- primidone
7
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substraten CYP2C19
benzodiazepines
citalopram
tricyclische antidepressiva
omeprazole
fenobarbital
8
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inhibitoren CYP2C19
- fluvoxamine
- fluoxetine
9
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inductoren CYP2C19
- rifampicine
10
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substraten CYP2D6
- codeïne
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inhibitoren CYP2D6
- bupropion
- cinacalcet
- fluoxetine
- kinidine
- paroxetine
- propafenon
- ritonavir
- terbinafine
12
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inductoren CYP2D6
- rifampicine
13
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substraten CYP3A4
- antihypertensiva
- immunosuppressiva
- antidepressiva
- antihistaminica
- statines
- oestrogenen
- oestroprogestagenen
- zolpidem
- methadon
14
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inhibitoren CYP3A4
pompelmoes (naringenine, furanocoumarines)
antimycotica (intraconazol, ketoconazol)
erythromycine
ritonavir
15
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inductoren CYP3A4
- hyperforine (sint-janskruid)
- rifampicine (PXR)
- carbamezipine
16
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substraten CYP2E1
- kleine organische molecules
- paracetamol
- ethanol
- fenobarbital
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inductoren CYP2E1
- chronisch ethanolgebruik