Pharmacokinetics Lecture Review Flashcards

This set of flashcards covers essential vocabulary and concepts from the pharmacokinetics lectures to aid in exam preparation.

Drug Elimination

The process of removing drugs from the body, including both drug excretion and metabolism.

Distribution

The process by which a drug reaches its site of action after entry into systemic circulation.

AUC

Area Under the Curve; represents total drug exposure over time.

Volume of Distribution (Vd)

A pharmacokinetic parameter that describes the distribution of a drug throughout the body's fluids and tissues.

First-Order Kinetics

A type of drug metabolism where the rate of elimination is proportional to the drug concentration.

Zero-Order Kinetics

A type of drug metabolism that occurs at a constant rate, regardless of the concentration.

Half-Life (t1/2)

The time required for the concentration of a drug in the body to reduce by half.

Clearance (CL)

The rate at which a drug is removed from the body, expressed in volume per time.

Bioavailability (F)

The fraction of an administered dose of a drug that reaches the systemic circulation.

Pharmacokinetics (PK)

The study of how drugs move through the body, encompassing absorption, distribution, metabolism, and excretion.