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core concepts in biology
life evolves overtime
matter and energy are transformed
biological processes go through information flow
structure and function are interconnected
biology consists of complex systems
macro similarities/differences
at the surface
micro similarities/differences
inner structures
what micro/macro similarities/differences prove
accounts for the unity and diversity of life
fossil record
indicates that life has changed over the course of the earth’s history
shallow layer = newer
deeper layer = older
descent with modification
differences from ancestry due to change in environment over time
produces adaptation to a local environment
natural selection
survival of the fittest
sexual selection
reproductive mate selection provides selective pressure
viral evolution
virus changes its genetic code overtime to adjust to the environment
artificial selection
humans provide selective pressure
biological organization
biosphere
ecosystem
communities
populations
organisms
organ
tissue
cell
organelles
molecules
biosphere
all life and the places where life exists on earth
ecosystem
living and nonliving things in a specific area
communities
array of organisms in a particular ecosystem
population
all individuals of specific species living in specific area
organisms
individual living things
organs
body part made of multiple tissues with specific function
tissues
clumps of cells that work together to carry out a specific function
cells
fundamental aspect of function and structure in life
organelles
inner structures in a cell
molecules
chemical structure with 2+ units of atoms
emergent properties
properties that occur when arrangement and interactions of parts become more complex
emergent properties examples
biosphere: nutrient cycling and climate regulation
ecosystem: interactions between living and nonliving
communities: array of organisms interacting
population: group dynamics, collective behavior
organisms: homeostasis and complex behavior
organ: organ function
tissue: coordinated tissue capability
cell: life itself
molecule: metabolic function
how can natural selection lead to two populations with features that are uniquely adapted to their environments
as the members of these two populations, who have traits that make it easier for them to survive to a specific environment, reproduce, their offspring inherits these traits and the cycle keeps going until these populations are fully adjusted
element
substance that can’t be broken down to other substances
comprised of single type of atom
compound
substance consisting of 2+ elements in a fixed ratio
composition of body
mainly oxygen
there is mostly water in our bodies = more oxygen
atoms
smallest unit of matter that retains properties of element
protons (identity of an atom), neutrons, electrons
neutral state = equal amount of protons and electrons
atomic number
number of protons
subscript (6C)
mass number
protons + neutrons
superscript (6C)
dalton
unit of weight for atoms (1.7 × 10-24)
protons and neutrons = 1 Da each
isotopes
elements with different number of neutrons
carbon-14
used to date archeological samples
earth’s atmosphere contains small and constant amount of c-14
in metabolic processes until death
half-life = 5,000
electrons and shells
occupy discrete shells
gains or loses energy to move across shells
inner shell = lower energy, making electrons more inclined to go towards its direction
valence electrons
electrons occupying outermost shell
determines the chemical behavior of an atom
atoms are more stable when their valence shell is fully occupied w/ electrons
amount of electrons in each shell
1st shell = 2 electrons
2nd and 3rd = 8 electrons
covalent bonds
atoms held together through shared valence electrons
molecule
2+ held together by covalent bonds
single bond
one pair of shared electrons
double bond
two pairs of shared electrons
electronegativity
tendency for an atom to attract shared electrons
FONCl BrISCH
fluoride
oxygen
nitrogen
chlorine
bromine (END OF HIGH)
iodine
sulfur
carbon
hydrogen
non-polar covalent bonds
small electronegativity
polar covalent bonds
high electronegativity
water and covalent bonds
contains two polar covalent bonds
partial negative in oxygen, partial positive for hydrogen
ionic bonds
attraction between opposite charges that occur when an electron is transferred from one atom to another
holds ionic compounds together
hydrogen bonds
result from attraction of partially positive hydrogen with partially negative charge on electronegative atom
van der waals interactions
attraction between nonpolar molecules based on transient regions of positive and negative charges
properties of water
water has strong adhesion, cohesion, and surface tension
resists temperature changes
ice is less dense than water
hydrophilic substances
loves water
fully/partially charged
hydrophobic substances
hates water
uncharged and nonpolar
acid
substance that donates H+ ions
base
substance that depletes H+ ions
pH scale
measure of hydrogen ion concentration
pH = -log[H+]
more H+ = more acidic, lower pH
less H+ = more basic, higher pH
classes of molecules
humans are also mostly carbon-based
basis of molecules
four classes
carbohydrates
lipids
nucleic acids
proteins
macromolecules: only carbs, nucleic acids, and proteins because they are able to form long polymer structures
polymer
repeating units linked by covalent bonds
monomer
building blocks of polymers
dehydration synthesis
removing water polymers to bond two polymers together
hydration synthesis
adding water to break down polymers
polymer diversity
diversity in variation of polymers is based on amount of monomers
ex: for dna, the 4 nucleotides and 10 polymers = 410
carbohydrates
function: store energy, energy source, cell structure
composition: includes sugars and sugar polymers
structure of carbohydrate affects function
ex: starch can be digested but cellulose can’t
lipids
function: energy storage, warmth, padding
composition: mostly non-polar hydrocarbons
saturated and unsaturated fats
structure: glycerol + three fatty acid chains
saturated fats: sold, dense, straight structure
unsaturated fats: liquid at room temperature, kink in the structure
phospholipid
structure: glycerol + two fatty acid chains + phosphate
hydrophilic head, hydrophobic tail
lipid bilayers
prevent the passage of hydrophobic substance
proteins
function: enzymes, communication, storage, transport, structure, defense, movement
composition: amino acids linked into polypeptides
amino acids
organic molecules w/ carboxyl and amino groups
20 amino acids vary in their r groups
enzymatic proteins
selectively speed up reactions
defense proteins
protect against disease
storage proteins
store amino acids
transport proteins
transport substances
hormonal proteins
coordination of organisms activities
structural
support
peptide bond
covalent bond between two amino acids
amino acids are joined to form polypeptides
polypeptides and folding
fold to form functional proteins
how it folds
ionic bonds
hydrophobic (inside) and hydrophilic (outside) bonds
primary structures
sequence of amino acids that are covalently bonded
secondary structures
folding of alpha helixes (coils) and beta pleated sheets (folds) in a polypeptide that are hydrogen bonded in place
tertiary structure
determined by interactions among amino acids and R groups/side chains
quaternary structure
bonding of multiple polypeptides into one structure
doesn’t occur for every protein
nucleic acid
function: information storage and transport
composition: nucleotides linked together into polynucleotides
DNA bases
pair w/ each other to form double-stranded helix
adenine and thymine
guanine and cytosine
RNA
ribose sugar
single stranded
uses uracil instead of thymine
predict how many covalent bonds an atom (hydrogen, oxygen, nitrogen, carbon) will form with other atoms in a molecule
hydrogen: one bond
oxygen: two bonds
nitrogen: three bonds
carbon: four bonds

match following structures
carbohydrate
protein
nucleotide
lipid
components of macromolecules
carbs: carbon, hydrogen, oxygen
protein: amino acids
nucleic acids: nucleotides
lipids: hydrocarbon chains, oxygen
cells
fundamental units of life
components of cells
all organisms are made of cells
the cell is the simplest collection of matter that can be alive
all cells are related by their descent from earlier cells
can differ substantially from each other, but share common features
magnification
get closer
contrast
intensity between two adjacent points
resolution
distance between two adjacent points and how close/far it takes to distinguish it as two entities
light microscope
uses visible light and beams it through specimen and then through class lenses
refracts light so image becomes magnified
staining and labeling enhance contrast
benefits/limitations of light microscope
benefits: cheaper, living organisms
limitations: can’t see inside
electron microscope
use electrons to produce image
scanning electron microscopes
beams electrons on specimen’s surface to create 3D strucutre
transmission
beams electrons through a specimen
benefits/limitations of electron microscope
benefits: can see inside organisms
limitations: can’t use living organisms, expensive
life is classified into two cell types
prokaryotes
bacteria
archaea
eukaryotes
protists
fungi
plants
animals
prokaryote traits
small
no membrane-bound organelles
single-celled organisms
no nucleus, DNA kept in unbound nucleoid region
most have call wall
eukaryote traits
larger cells
multicellular
DNA in nucleus, surrounded by nuclear envelope
some plants have cell wall (plants, algae)
both prokaryotes and eukaryotes
plasma membrane
cytosol
chromosomes
ribosomes