schizophrenia

0.0(0)
studied byStudied by 0 people
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
Card Sorting

1/5

encourage image

There's no tags or description

Looks like no tags are added yet.

Study Analytics
Name
Mastery
Learn
Test
Matching
Spaced

No study sessions yet.

6 Terms

1
New cards

what increases risk

adolescent activation of microglia via 4A complements

2
New cards

what are the symptoms

  1. +ve symptoms: auditory and visual hallucinations, thought broadcasting, inability to distinguish fiction from reality

  2. -ve symptoms: social withdrawal, catatonia and depression

3
New cards

what causes +ve symptoms

increased dopamine in the mesolimbic system

  1. involves nucleus accumbens and ventral tegmental area

  2. binds to D2 receptors in the substantia nigra pars compacta

  3. decreased inhibition to GABA neurons originating from striatum

  4. decreased inhibition of thalamus → decreased thought filtering

4
New cards

what else can cause +ve symptoms

parkinsons medication

5
New cards

what causes -ve symtpoms

  1. decrease dopamine in mesocortical pathways

  2. hypofrontality syndrome → decreased bloodflow to prefrontal cortex

6
New cards

glutamate hypothesis?

  1. defective NMDA receptors causes increased release of glutamate

  2. +ve mesolimbic system: increase glutamate stimulates the release of dopamine

  3. 3. -ve mesocortical system: increased glutamate inhibits release of dopamine