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what are reasons that someone would be in the ICU?
airway, breathing, circulation, + neurologic
what is the apache II score?
measures how sick someone is
what is a huge risk factor for mortality?
age
what is the sofa score used to measure?
septic pts level of sickness
what are adv effects of the ICU?
severe weakness, 40% require mechanical ventilation, cognitive impairments, psych issues, cost
what are short term psych issues?
delirium
what are long term psych issues?
depression, anxiety, PTSD
what puts someone at a higher risk of ICU adv effects?
longer stays, longer time on ventilation, incr age
what are 2 types of severe weaknesses that can result from ICU stays?
critical illness myopathy (CIM), critical illness polyneuropathy (CIP)
what are SXS of ICU morbidity?
CIM, CIP, persistent critical illness acquired weakness (CAW), reduced fxn 6-12 mo post discharge, reduced mm strength seen in many survivors for 5y or more, cost
what is the biggest risk factor that can lead to critical illness myopathy (CIM)?
sedatives/sedation; avoid as much as possible
people in the ICU are unable to deliver O2 well, so what process is used more?
glycolysis
what does stress incr?
cortisol levels
what are some factors that can lead to critical illness myopathy?
septic shock, poor glycemic control, multi-organ failure, pre-existing alcoholic myopathy, NM blocking agents, sedatives/analgesics, steroids
what is a trigger factor that can lead to sepsis?
steroid toxicity
what are predisposing factors that can lead to sepsis?
TNF alpha, IL-6, cortisol
what are priming factors that can lead to sepsis?
denervation CIP, NMBAs membrane hypoexcitability
what is considered the highest risk factor (out of the list) leading to CIM?
sedatives/sedation → avoid as much as possible
what specific sedatives should you factor? what should you stay away from?
favor short acting sedatives like propofol and precedex → stay away from benzodiazepines
what mm wasting is found c ICU stays? what causes it?
dec in type 1 fibers occurs → d/t decr calorie intake
what is used sometimes to make sure pts are receiving proper calorie counts?
feeding tubes
what is the medical research council (MRC)?
measures weakness for critical illness acquired weakness (CAW) → scale out of 60, measures 3 MMTs for the LE/UE B and adds up the score
what are common LE mm involved c MRC?
hip flex, knee ext, ankle DF
what are common UE mm involved c MRC?
shoulder aBD, elbow flex, wrist ext
what LE gait deviation is seen a lot post ICU?
foot drop
what is a motomed device?
used in bed for movement/exer; can be used c e-stim
what are risk factors for developing CAW?
myopathies/neuropathies (or both)
what are barriers to exer within the ICU?
deficit of practitioner knowledge, poor culture of institutional/med team, not enough time or staff, pt factors
what are factors to practitioner knowledge deficits?
training, equip, inconsistent PT practice in ICU
what are factors that affect pt barriers to mobility in ICU?
sedation, neurocognitive status and stability, bleeding, fx stability
t/f: many people are acidotic within the ICU, which could cause a barrier for exer
true
describe the bohr effect
- when pH decr → more acidic → CO2 incr → less saturation of O2 occurs and more is available for mm
- when pH incr → less acidic → CO2 decr→ more saturation of O2 occurs and less is available for mm
does the bohr affect shift to the right or left c exer?
right
what can acidity of ICU pt lead to?
anemia → there is not enough O2 traveling through the blood
what do PTs need to monitor before starting exer c ICU pt?
BP, HR, SpO2
what should pts SpO2 be at for exer in the ICU?
high 80s and low 90s
what is involved c involuntary breathing control?
the NS (basal rate), chemical factors
what are neural structures that are involved c involuntary breathing control?
brainstem, phrenic nerve
what does the phrenic nerve innervate?
diaphragm (CN 3, 4, 5)
what are the chemical receptors that are involved c involuntary breathing control?
H+, PaCO2, PaO2
what chemical receptor is the strongest driver of involuntary breathing control?
PaCO2 elevation
mechanical receptors are ___ receptors
stretch
what is the minimal MAP for exer in ICU pt? normal MAP?
minimal = 65; normal = 70-100
what helps prevent acidosis?
hydrogen ion buffering
what is normal pH?
7.35-7.45
what are buffers that help keep pH normal?
weak acids/bases
what are the 2 primary organs that regulate pH?
lungs and kidneys
what is hydrogen ion buffering?
when pH incr, the lungs incr ventilation and blow off CO2 (decr H+); kidneys reabsorb HCO3-, secreting H+
what happens if pH incr too much?
kidneys will remove HCO3- and retain H+; lungs decr ventilation and retain CO2 to incr H+
what is respiratory acidosis?
ventilation failure (hypoventilation)
what is acute respiratory acidosis?
when CO2 builds up very quickly before the kidneys can return the body to a state of balance
what is respiratory alkalosis?
hyperventilation d/t acute CNS injury, high altitude, anxiety, etc
what is metabolic acidosis caused by?
lactic acidosis, ketoacidosis, kidney failure
what causes metabolic alkalosis?
excessive vomiting
what is carbaminohemoglobin?
carried on globin protein, not attached to iron (Hb can carry 4 O2 & 4 CO2)
how do you determine if somebody is ready to be mobilized in the ICU?
awake? able to minimally participate, stable hemodynamics, normal tissue O2, ICP stable, no active bleeding, stable fx, special circumstances
what is the ABCDEF ICU safety bundle for treatment?
assess & address px, both awake + breathing, choice of analgesia/sedation, delirium, early mob/exer, family
what are the two steps of the level of consciousness assessment for evaluating readiness for exer?
perform RASS scale, perform a delirium assessment
t/f: you want to be a zero on the RASS scale
true
what is the RASS scale?
+4 to -5 scale
- positives mean the pt is too agitated
- negatives mean the pt is too sedated
what are "good" scores for rehab ont he RASS scale?
+2 or -2
what does a -2 mean on the RASS scale?
eyes open to voice
what is the CAM-ICU?
assesses delirium that can be associated c worse prognosis, incr morbidity/mortality in ICU pts
- able to answer questions c out needing to speak
what has been shown to be able to reduce delirium?
early mobility and exer
how does delirium effect pt prognosis?
declines
what is the FSS-ICU?
5 categories: rolling, supine to sit, unsupported sitting, sit to stand, amb (score 0-7 for each)
what is the PFIT?
looks at fxn, strength, endurance in ICU pts; measured 3 times: awakening, ICU discharge, and hospital discharge
what does the PFIT look at?
sit to stand, marching on spot, strength (shoulder flex, knee ext)
what are the uses of the PFIT?
look at prognosis, look at progression of interventions
what is the Perme ICU mobility score?
factors both fxn and ICU support level; 0-32 c 32 = best; 7 categories
how can perme ICU mobility score be increased?
c improved fxnal mobility OR decr in ICU support (may impact mobility)
what is the chelsea critical care phys assessment tool?
assess phys and respiratory fxn and morbidity; 0-5 scale, 8 categories
what lines/leads does CPAx take into account?
ventilators and supplemental O2
what lines/leads does the perme ICU mobility score take into account?
ventilators, drips, catheters, supplemental O2
phase 1 of ICU mobility/walking program:
bed exer, stretcher chair, unable to bear wt
phase 2 of ICU mobility/walking program:
transfers & pre gait/walking in room
phase 3 of ICU mobility/walking program:
walking out of the room
phase 4 of ICU mobility/walking program:
out of ICU, preparing for discharge
what is the vanderbilt protocol of treatment for a pt with RASS score of -5/-4?
PROM
what is the vanderbilt protocol of treatment for a pt with RASS score of 3-/2-?
PROM, sitting
what is the vanderbilt protocol of treatment for a pt with RASS score of -1/0/+1?
AROM, exer, sit, stand, walk, ADLs
what are the risk factors for PICS?
incr age, sepsis, corticosteroids, sedatives, delirium
what are the consequences of PICS?
long term deficits in IADLs, difficulty returning to work
what are the benefits of exer in the ICU?
decr PICS effects, incr survival/decr mortality rates
what are barriers to earliy mobility in the ICU?
staff culture, overuse of sedation, false perception that people are "too sick", lack of staff/PT training/lack of confidence
how is readiness for mobility in ICU assessed?
- RASS/CAM
- ability to follow simple commands to ensure safety of leads/lines/procedure
- MAP > 60 mmHg/hemodynamic stability
- SpO2 high 80s low 90s