Soft Tissue Tumors

STS stand for

Soft Tissue Sarcoma

On what type of tissue do soft tissue sarcomas occur in?

extraskeletal connective tissue

What is extraskeletal connective tissue? Give examples

All the tissues that provide connection, support & locomotion.

e.g. muscle & fat

Why are all sarcomas staged differently than carcinomas?

Cuz they are less likely to go to the nodes

(so no TNM staging)

STS are classified ___-

histologically

STS are named according to ___

the tissues in which they arise (e.g. liposarcoma)

What is the most important predictor of outcome?

Histologic grade

Which is why accurate determination of it is very important

What are the 6 types of STS? mnemonic

Good

Kids

Love

Fiber

Rich

Diets

What are the 6 types of STS?

Good: Genitourinary

Kids: Kaposi’s Sarcoma

Love: Liposarcoma

Fiber: Fibrosarcoma

Rich: Rhabdomyosarcoma

Diets: Desmoid Tumors

Fibrosarcomas originate from?

Which STS originates from connective tissue of nerve sheaths?

Where are desmoid tumors predominantly found?

Which STS is predominantly found in the Rectus abdominus muscle in young women?

Which of the 6 STS discussed is benign?

Desmoid Tumor

What is the most common STS?

Liposarcoma

Where can liposarcomas occur?

Which STS can occur anywhere where fat is present?

Term. Lipoma

def. benign tumor of fat

Which is benign which is cancer?

1. Lipoma

2. Liposarcoma

1. Lipoma- benign

2. Liposarcoma- cancer

Which of the 6 STS discussed is radiosensitive (so could essentially be tx with RTT)?

Liposarcoma

Which of the 6 STS is the most lethal (i.e. has the poorest prognosis)?

Rhabdomyosarcoma

What organ is the most common site of presentation for sarcomas of the genitourinary tract?

Uterus

What genitourinary tract STS is the most frequent histological type?

leiomyosarcoma (smooth muscle)

Kaposi’s Sarcoma appearance

What STS appears as Soft purplish eruptions on the skin

Most common location where Kaposi’s Sarcoma appears

Extremity

What are the 2 types of Kaposi’s sarcomas?

1. True Kaposi’s sarcoma: typically seen in Mediterranean & North African men over 65 y/o

2. Another form seen in AIDS patients