FAM exam 6 - cows and mini goats

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<p><span>Goat intestinal parasites</span></p>

Goat intestinal parasites

  • MOA: GI nematodes, flukes, lungworms, barber pole worm

  • CS: Weight loss, poor growth, anemia, poor hair coat, submandibular edema/ bottle jaw, diarrhea.

  • ID: Fecal examination, Fecal egg count, FAMACHA

  • TX: Albendazole + Levamisole, Albendazole + COWPs, Levamisole + COWPs

    • Only when CS appear

  • Prevention:

    • Young: 4-6w, 8-12w of age

    • Adults: q 6-12m dewormed

    • Fecal egg counts (FEC)

    • Avoid over grazing

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Goat Mange

  • Psoroptic: Ear lesions, pruritic→ head shaking/rubbing, alopecia, redness, crust

    • non burrowing

  • Chorioptic: leg/abdomen lesions, pruritic→ restlessness, alopecia, redness, crust

    • non burrowing

  • Demodectic: facial lesions, non pruritic→ papules/nodules: gray waxy material(mites found here)

  • TX: 

    • Ivermectin, moxidectin, eprinomectin 

    • Topical Dips: Coumaphos/ Toxaphene/ Lime sulfur/ Phosmet 

      • q 2x  5-7 days apart

      • secondary pyoderma: antibiotic therapy

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<p><span>Lice Infestation In Goats</span></p>

Lice Infestation In Goats

  • Lice Infestation (Pediculosis)→ sucking/chewing

  • CS: Pruritus, alopecia, skin damage, anemia, loss of condition

  • TX: improve BCS/housing, late summer or fall, whole herd, repeat 2× 5-7 days apart

    • Biting Type: Synthetic pyrethroids (methrin), Coumaphos, Malathionor

    • Sucking Type: Ivermectin(systemic), doramectin

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<p><span>Dermatophilosis</span></p>

Dermatophilosis

  • AKA: Streptothricosis, Lumpy Wool Disease, Rain Scald, Rain Rot

  • MOA: Dermatophilus congolensis, contact, biting insects, skin abrasions, moisture

  • CS: Papules, pustules,"paintbrush" crusts, not pruritic, but painful

  • ID: Gram stain, morphology(branching filaments), culture, histopath

  • TX: Oxytetracycline, Topical iodine/ chlorhexidine, Vax, keep dry, good diet

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<p><span>Staphylococcal Dermatitis in Goats</span></p>

Staphylococcal Dermatitis in Goats

  • CS: Nonpruritic lesions on head and face, alopecia, papules, crusts, ulcers, erythema, exudation, hyperpigmentation, skin thickening

  • ID: Culture, histopath

  • TX: Pen G, Oxytetracycline, enrofloxacin, lincomycin-spectinomycin, topical iodine/ chlorhexidine

  • Prevention: control flies, isolate affected

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<p><span>Dermatophytosis (Ringworm) in Goats</span></p>

Dermatophytosis (Ringworm) in Goats

  • MOA: Trichophyton verrucosum

    • Zoonotic, direct contact

  • CS: Circular areas of hair loss, scaling, crusting

  • ID: CS, Fungal culture

  • TX: isolation, griseofulvin, Enilconazole, Lime sulfur, iodine, sodium hypochlorite (bleach), Sun exposure

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<p><span>Seborrhoeic Dermatitis in Goats</span></p>

Seborrhoeic Dermatitis in Goats

  • MOA: unknown

  • CS: Non-pruritic scaling and crusting: around the eyes, ears, nose and head, and in the axilla, groin and perineal region

  • TX: antibiotics, methylprednisolone acetate, corticosteroid

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Bacti Pneumonia in Goats

  • MOA: Pasteurella multocida, Mannheamia haemolytica, Mycoplasma

  • CS: Fever(>104), Coughing, Nasal discharge, Difficulty breathing, Weakness

  • ID: Auscultation(crackling/wheezing), X-ray, tracheal wash(culture)

  • TX: Antibiotics, NSAIDs, Supportive care, Vax, Ventilation

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Viral Pneumonia in Goats

  • MOA: Parainfluenza 3(PI3), Adenovirus, Respiratory Syncytial Virus(RSV), Caprine Herpesvirus

  • CS: coughing, nasal discharge, anorexia, fever, conjunctivitis, tachypnea, tachycardia

  • ID: virus isolation, serology

  • TX: supportive, intranasal vax

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<p><span>Keratoconjunctivitis in Goats</span></p>

Keratoconjunctivitis in Goats

  • MOA: Chlamydophila, Mycoplasma 

    • Highly contagious 

  • CS: Epiphora (tearing), redness, mucopurulent discharge, keratitis

    • Herd wide Mastitis, Polyarthritis, Pleuropneumonia

  • ID: Cytology, IFA, Culture

  • TX: Oxytetracycline + Polymyxin B(eye meds), NSAIDs (Flunixin/Meloxicam), eye patch

  • Prevention: fly control, vax

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<p>Caprine Arthritis Encephalitis (CAE)</p>

Caprine Arthritis Encephalitis (CAE)

  • MOA: Lentivirus

  • CS: 

    • Kids 2-6m →1y: Progressive weakness, leukoencephalomalacia!

    • Adults: chronic arthritis carpal joints, hard bag, pneumonia

  • ID: ELISA, AGID, PCR

  • TX: Aspirin, Flunixin meglumine, Euth,

  • Prevention: isolate @ birth, pasteurized colostrum

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<p><span>Paratuberculosis (Johne's Disease) in Goats</span></p>

Paratuberculosis (Johne's Disease) in Goats

  • MOA: Mycobacterium avium 

  • CS: Weight loss, rough hair coat, submandibular edema, weakness, anemia

    • don’t appear until 2-4 years of age

  • ID: Fecal PCR testing, necropsy, thickened intestine/large lymph nodes

  • TX: none, pasteurize colostrum, test/cull

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<p>Caseous Lymphadenitis in Goats (CL)</p>

Caseous Lymphadenitis in Goats (CL)

  • AKA: Cheesy Gland

  • MOA: Corynebacterium pseudotuberculosis

    • Via Skin breaks

  • CS: chronic weight loss, external abscesses

  • ID: Culture, serology

  • TX: Pen G, Oxytetracycline drain w/ iodine lavage, isolate, clean shearing equipment

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Mycoplasma in Goats

  • MOA: Mycoplasma mycoides subsp. capri (highly pathogenic) , M. putrefaciens(less common)

    • Lifelong intermittent shedding

    • Shed after stress

  • CS: Mastitis, arthritis, pneumonia, meningitis, abortion

  • ID: Culture milk/joint fluid

  • TX: none

  • Prevention: test/cull/replacement herd

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Tetanus in Goats

  • Clostridium Tetani

  • MOA: Wound infection

  • CS: Lockjaw, muscle spasms, especially in neck, limbs, and back, difficulty breathing, seizures, death

  • ID: History of injury.

  • TX: Tetanus antitoxin, antibiotics, muscle relaxants, sedatives,

  • Prevention: vax

    • Poor prognosis

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Mastitis in Goats

  • MOA: 

    • Staphylococcus aureus(severe)/agalactiae/uberis(mild)

    • Mycoplasma(systemic)

    • Escherichia coli(severe)

    • Coagulase-negative Staphylococci(mild/chronic

  • CS: Heat, pain, swelling, abnormal milk

  • ID: Clinical signs, CMT

  • TX: antibiotics, frequent stripping out, oxytocin injections, NSAIDs,

  • Prevention: pre/post teat dip, clean udders/hands

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Acute Rumen Acidosis in Goats

  • MOA: drastic diet change, too much grain/corn

  • CS: Bloat, abdominal distension, dehydration, tachycardia, tachypnea, lethargy, recumbency and death

  • TX: Rumenotomy(early), transfaunation, antibiotics, vit B, IV/oral fluids

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<p><span>Pregnancy Toxemia in Goats</span></p>

Pregnancy Toxemia in Goats

  • MOA: High energy demand late in pregnancy

    • especially w/ multi kids

  • CS: Depression, teeth grinding, star-gazing, incoordination, recumbency, and death

  • ID: detect ketone in urine or milk

  • TX: propylene glycol, vit B, calcium borogluconate, transfaunation, C-section/induction/abortion → 30-36h later

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Polio in Goats

  • MOA: 

    • Primary: Thiamine deficiency, sulfur toxicity

    • Secondary: Excessive grain, rumen acidosis

  • CS: Stargazing, circling, head pressing, blindness, nystagmus, convulsions, death

  • TX: Thiamine, probiotics, brewer’s yeast

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Diarrhea in Neonatal Goats

  • MOA: E. coli, Rotavirus, Cryptosporidium, Salmonella, Giardia, Nutritional 

  • CS: Dehydration, liquid stools, Fever, Depression, Tenesmus

  • ID: Fecal, culture, serotyping, Histopath, IFA

  • TX: IV Fluids, Trimethoprim-Sulfonamide, Oxytetracycline, Metronidazole, Neomycin sulfate, NSAIDs, Probiotics, Vax

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<p><span>Coccidiosis in Neonatal Goats</span></p>

Coccidiosis in Neonatal Goats

  • CS: Thin kids, diarrhea , anemia, rough hair coat, weakness, dehydration, stunted growth, death

  • ID: fecal flotat

  • TX: Amprolium, Decoquinate, Benzeacetonitrile (-azurill), sulfadimethoxine, sulfadimidin

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Navel ill and Septic joints in Neonatal Goats

  • MOA: Infection of the umbilicus.

  • CS: Swollen umbilicus, swollen joints, reluctance to move, failure to gain weight.

  • TX: antibiotics, joint lavage, surgical removal of the umbilicus,

  • Prevention: navel dip

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<p><span>Contagious Ecthyma in Neonatal Goats</span></p>

Contagious Ecthyma in Neonatal Goats

  • AKA: Sore mouth

  • MOA: Orf virus

  • CS: Painful lesions around mouths/teats, anorexia

  • TX: antibiotics, NSAIDs,

  • Prevention: Vax (live) → only if dz is present

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Septic Meningitis

  • MOA: Bacti sepsis, Failure of passive transfer, umbilical infections, poor hygiene

    • (E. coli, Pasteurella spp., Salmonella spp)

  • CS: Depression, fever, inappetence, Stiff neck, opisthotonos (arched back), Ataxia, tremors, seizures, Blindness, altered mentation

  • ID: Culture, CSF Analysis

  • TX: Antibiotics, NSAIDs, Fluids, Plasma transfusion, Vax

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Dystocia in Goats

  • Difficulty in delivery, requiring assistance

  • MOA: Fetal malpositioning, fetal disproportion, multi fetuses, incomplete cervical dilation (ringwomb), uterine inertia, and uterine torsion.

  • TX: C-sections(common), manual correction→ cervical dilation(<30%), manipulation, Oxytocin(careful with close cervix’s), NSAIDs, Antibiotics

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Urolithiasis in Goats

  • MOA: Goats normally have alkaline urine

    • Phosphatic calculi (struvite): grain diets

      • MOST COMMON

    • Calcium carbonate: legume diets

  • More prominent if neutered b4 3m

  • Common sites: Urethral process; sigmoid flexure

  • CS: Straining to urinate, tail pumping, blood/crystals on preputial hairs, anorexia, lethargy, urethral rupture leading to potbelly appearance, bladder rupture 

    • ID(rupture): xray, abdominocentesis, US, creatine ratio: blood/fluid

  • TX: Med management(not enough), Urethral process amputation, urethrostomy, cystostomy, bladder marsupialization(ruptured urethra), increase salt in the diet, ammonium chloride

    • Urethral process amputation, cystostomy: good kidney function, bladder/urethra is intact → good long term prognosis

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<p><span>Copper Toxicosis in Goats</span></p>

Copper Toxicosis in Goats

  • CS: Anorexia, depression, diarrhea, weakness, hemoglobinuria, icterus.

  • ID: Serum copper concentrations, liver and kidney copper levels.

  • TX: Supportive care, fluid therapy, ammonium, sodium thiosulfate

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Foot Rot in Goats

  • MOA: Fusobacterium necrophorum, Dichelobacter nodosus, wet enviro, overgrown hooves

  • CS: Lameness, necrotic lesions in the interdigital space w/ foul odor.

  • TX: penicillin, oxytetracycline, formalin/zinc sulfate foot bath, farrier work, dry enviro

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Degenerative Joint Disease in Goats

  • Common in geriatric goats

  • CS: Stiff gait, reluctance to walk, overgrown hooves, progressive lameness 

  • TX: Polysulfated glycosaminoglycan, Phenylbutazone, Aspirin, Hoof trimming, weight management

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<p><span>Ventricular septal defect (VSD)</span></p>

Ventricular septal defect (VSD)

  • MOA: #1 congenital heart defect of ruminants

    • Herefords, Limousins, Jersey cattle

  • CS: Calves: ocular anomalies, tail anomalies, resp distress, poor growth, right side murmur

    • Some VSDs can be large with significant shunting of blood (Mostly L to R)

  • ID: US, necropsy

  • TX: euth (grave)

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<p><span>Tetralogy of fallot</span></p>

Tetralogy of fallot

  • MOA: Right to left shunt

  • CS: cyanosis, exercise intolerance, dyspnea, Polycythemia

  • MOA: euth (grave)

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<p><span>Neoplasia of the Bovine Heart</span></p>

Neoplasia of the Bovine Heart

  • MOA: lymphosarcoma involving the 1) right atrium in cows 3-4y

    • 2) abomasum, 3) uterus, 4) CNS

  • CS: Tachycardia, Atrial fibrillation, murmurs, heart failure, distended jug v. ,brisket edema/bottle jaw(ventral)

    • White nodules or streaks within the myocardium

  • ID: AGID, US, necropsy

  • TX: euth (grave)

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<p><span>Cardiomyopathies</span></p>

Cardiomyopathies

  • MOA:

    • Primary: Genetic -RARE

      • Red Holstein, Ayrshire cattle

    • Secondary: toxicity- MOST COMMON

      • oleander, Monensin, lasolacid, cottonseed

  • CS: CHF, brisket edema/bottle jaw

    • abnormal jugular vein

  • TX: digoxin, fluids, rumenotomy (6-12hr if toxic)

    • poor-grave prognosis

<ul><li><p><span style="color: green"><strong>MOA:</strong></span></p><ul><li><p><strong>Primary: </strong><u>Genetic -RARE</u></p><ul><li><p>Red Holstein, Ayrshire cattle</p></li></ul></li><li><p><strong>Secondary: </strong><u>toxicity- MOST COMMON</u></p><ul><li><p><strong><u>oleander, Monensin, lasolacid, cottonseed</u></strong></p></li></ul></li></ul></li><li><p><span style="color: green"><strong>CS:</strong></span> <strong>CHF</strong>, <u>brisket edema/bottle jaw</u></p><ul><li><p><u>abnormal jugular vein</u></p></li></ul></li><li><p><span style="color: green"><strong>TX: </strong></span>digoxin, fluids, <strong><u>rumenotomy (6-12hr if toxic)</u></strong></p><ul><li><p><u>poor-grave</u> prognosis</p></li></ul></li></ul><p></p>
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<p><span>Vitamin E/selenium Deficiency</span></p>

Vitamin E/selenium Deficiency

  • MOA: Acute muscle degen of rapidly growing calves

  • CS: Resp distress, arrhythmias, sudden death, Elevated cTnI

  • TX: Selenium w/ vit E injections, supplement

    • fair to good prognosis

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Infectious Myocarditis

  • MOA: Histophilus somnus - vasculitits

  • CS: Sudden death, depression, pyrexia, foaming at mouth, dyspnea

  • ID: Histopath - see colonies in tissue

  • TX: Tulathromycin/ tetracyclines/ enrofloxacin (antibiotics), NSAIDs, fluids

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<p><span>Endocarditis</span></p>

Endocarditis

  • More common the myocarditis

  • MOA: tricuspid valve of Dairy Cattle than any other species

    • bacti infection

  • CS: intermittent fever, tachycardia, systolic heart murmur for a long time, pounding heart sounds

  • ID: Anemia(non-regen), Neutrophilia(mature), High Gb + fibrinogen, US, Bld culture

  • TX: >3w of ceftiofur (antibiotics), Furosemide, NSAIDs

    • Guarded to poor prognosis

      • w/ ventral edema, right heart failure

<ul><li><p>More common the myocarditis</p></li><li><p><span style="color: green"><strong>MOA:</strong></span> <strong><u>tricuspid valve</u> </strong><u>of </u><strong><u>Dairy Cattle</u> </strong>than any other species</p><ul><li><p><u>bacti</u> infection</p></li></ul></li><li><p><span style="color: green"><strong>CS:</strong></span> <strong><u>intermittent fever</u></strong>, tachycardia, <strong><u>systolic heart murmur for a long time,</u></strong> <strong>pounding heart sounds</strong></p></li><li><p><span style="color: green"><strong>ID</strong></span>: <strong>Anemia(non-regen)</strong>, Neutrophilia(mature), <strong><u>High Gb + fibrinogen</u></strong>, US, Bld culture</p></li><li><p><span style="color: green"><strong>TX:</strong></span> <strong><u>&gt;3w of ceftiofur</u> </strong><u>(antibiotics)</u>, Furosemide, NSAIDs</p><ul><li><p><u>Guarded </u>to poor prognosis</p><ul><li><p>w/ ventral edema, right heart failure</p></li></ul></li></ul></li></ul><p></p>
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<p><span>Pericarditis</span></p>

Pericarditis

  • MOA: traumatic reticulopericarditis

  • CS: Jugular vein distention, tachycardia, splashing heart sound, fever, painful stance, brisket edema/bottle jaw

  • ID: Withers pinch test (x3), bar test, grunt test, X-ray, US, culture

    • Pericardiocentesis: smells, high TP(>8.5) + fibrinogen(>850) + SG + WBC

      • 5-6 ICS right side

  • TX: antibiotics, NSAIDs, magnets (give @ 4-8m old), SX (Rumenotomy/ Thoracotomy/ pericardiectomy) - not practical

    • Prognosis is poor

<ul><li><p><span style="color: green"><strong>MOA</strong></span><span style="color: red"><strong>:</strong></span> <strong><u>traumatic reticulopericarditis</u></strong></p></li><li><p><span style="color: green"><strong>CS:</strong></span><strong> </strong>Jugular vein distention, tachycardia, splashing heart sound, <strong>fever, painful stance, brisket edema/bottle jaw</strong></p></li><li><p><span style="color: green"><strong>ID:</strong></span> <strong><u>Withers pinch test (x3), bar test, grunt test</u></strong><u>, </u>X-ray, US, culture</p><ul><li><p><strong><u>Pericardiocentesis:</u></strong><u> smells, </u><strong><u>high TP(&gt;8.5) + fibrinogen(&gt;850)</u></strong><u> + SG + WBC</u></p><ul><li><p><strong><u>5-6 ICS right side</u></strong></p></li></ul></li></ul></li><li><p><span style="color: green"><strong>TX:</strong></span> <strong><u>antibiotics,</u></strong> NSAIDs, <strong><u>magnets (give @ 4-8m old),</u></strong> SX (Rumenotomy/ Thoracotomy/ pericardiectomy) - not practical</p><ul><li><p>Prognosis is <u>poor</u></p></li></ul></li></ul><p></p>
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<p>SR <span>Pericardial Effusion (Heartwater)</span></p>

SR Pericardial Effusion (Heartwater)

  • MOA: Ambyloma ticks

  • CS: fever, resp distress, edema

  • TX: Tetracycline - if given early

    • difficult to control

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<p><span>Brisket edema; Mountain Sickness; High Mountain Dx</span></p>

Brisket edema; Mountain Sickness; High Mountain Dx

  • right ventricular hypertrophy

  • MOA: only "herd" cardio dx

    • COR pulmonale (R ventricular hypertrophy), genetic, grazing Astragalus/Oxytropis (locoweed)

  • CS: dyspnea, tachycardia, ventral edema, jugular pulsations

  • ID: US, TTW, X-ray, measure PA pressure

    • DDX: other ‘carditis’, pneumonia

  • TX: lower elevation, TX lung dx, Breed the low PA pressure bulls

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Arrhythmias

  • Dairy cattle

  • MOA: atrial fibrillation

    • GI problems w/ high vagal tone, hypokalemia, hypocalcemia, metabolic alkalosis, lymphoma

  • ID: irregularly irregular rhythm, high HR, ECG

  • TX: correct GI support, fluids, Ca solutions, KCl

  • Most likely a 2ndary heart problem

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arrhythmia associated with high electrolytes

  • hypercalcemia

    • MOA: Rapid IV Ca for milk fever TX

      • careful with IV calcium - issues

    • CS: Bradycardia, Ectopic beats, Death 

    • TX: atropine

  • hyperkalemia

    • MOA: Calves w/ acute diarrhea

    • CS: arrest of ventricular rhythm 

    • ID: No P waves

    • TX: bicarbonate, dextrose solutions to drive potassium intracellularly

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<p><span>Thrombosis and Phlebitis</span></p>

Thrombosis and Phlebitis

  • Dairy cattle

  • MOA: Traumatic venipuncture by owner

    • Ca, dextrose, phynelbutazone, oxytocin, tetracycline, IV NaI

  • CS: Local swelling, Fever, Abscess, Skin sloughing, Anorexia, Tachycardia, Edema

  • TX: compress, inject site w/ NS, Antibiotics, NSAIDs

    • Prognosis is guarded

<ul><li><p>Dairy cattle </p></li><li><p><span style="color: green"><strong>MOA</strong></span>: <strong><u>Traumatic venipuncture&nbsp;by owner</u></strong></p><ul><li><p><strong>Ca, dextrose, phynelbutazone, oxytocin, tetracycline, IV NaI</strong></p></li></ul></li><li><p><span style="color: green"><strong>CS:</strong></span> Local swelling, Fever, Abscess, Skin sloughing, Anorexia, Tachycardia, Edema</p></li><li><p><span style="color: green"><strong>TX:</strong></span> compress, inject site w/ NS, Antibiotics, NSAIDs</p><ul><li><p>Prognosis is<u> guarded</u></p></li></ul></li></ul><p></p>
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<p><span>Anemia</span></p>

Anemia

  • MOA:

    • Bld loss: Ruptured uterine a., SR parasites

      • shock = >30% loss

    • IV hemolysis: see hemoglobinuria, Heinz body(methemoglobinemia)

      • Onion , Allium, Brassica, lepto

    • EV hemolysis: no hemoglobinuria

      • Anaplasmosis, mycoplasmas

  • CS: Fever, icrurus, weakness, polypnea, tachycardia, anxiety, MM pallor, hemorrhagic shocks

  • TX: transfusion

    • no cross match: no alloantibodies ab

    • indicated PCV < 15%

    • Donor: BSC >4, dry, >1m post calving, BLV/anaplasmosis neg

      • give 12g of Na citrate in 300 mL saline, 5L of blood

    • Recipt: 5L cow; 500ml SR

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<p><span>Copper Toxicity</span></p>

Copper Toxicity

  • MOA: sheep/SAC, molybdemum

  • cow/goats resistant

    • copper stored in liver

      • Under stressful situations copper released into blood

        • Hepatic necrosis and intravascular hemolysis

  • CS: peracute hemolytic shock, sudden death, lethargy, weakness, icteric sclera, pale MM, Hemoglobenuria, arched back from kidney pain

    • gun meatal kidney

  • ID: liver Cu > 150 ppm, kidney Cu > 15 ppm

  • TX: Penicillamine(orally), Vit C, Ammonium molybdate (3w)

    • prevention: correct diet, supplement (copper)

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Bacillary Hemoglobinuria

  • Gram +, dairy/meat cows

  • MOA: Clostridium hemolyticum, liver fluke

    • intravascular

  • CS: anemia, hemoglobinuria, sudden death

  • ID: liver necrosis, anemic infarct in liver, discolored kidney

  • TX: Antitoxin, Penicillin, transfusion, Vax, prevent flukes

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<p><span>Anaplasmosis</span></p>

Anaplasmosis

  • AKA: Yellow fever

  • MOA: only cattle tick dx in USA

    • anaplasma marginale, centrale, bovis, ovis

    • common in S-E/N-W states

    • extravascular hemolysis

  • CS: sudden death, abortions, anemia, pale MM, anorexia, incoordination, breathlessness, rapid bounding pulse

  • ID: bld smears, PCR

  • TX: Oxytetracylcine, tick prevention

    • lifelong carriers

    • No vax

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Mycoplasma haemolamae (Hemoplasmas)

  • MOA: Unique to SACs, goats

    • Transmitted by ticks

    • Extravascular hemolysis 

  • CS: Fever, anemia, depression, icterus, infertility, edema, poor growth

  • TX: Oxytetracycline suppresses infection, but doesn’t eliminate it, Bld transfusion

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Babesiosis,Texas cattle fever, Tick fever, piroplasmosis

  • MOA: Ticks, Mexico, zoonotic

    • transmitted by the cattle fever tick Rhipicephalus (Boophilus)

  • CS: anorexia, depression, fever, anemia, red urine

  • TX: Diminazene, imidocarb(not in the usa), NSAIDs, IV fluids, transfusion

    • notifiable

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<p><span>Trypanosomiasis</span></p>

Trypanosomiasis

  • MOA: Tsetse/biting flies

    • sleeping sickness - zoonotic

  • CS: Fever, anemia, weight loss, lymphadenopathy

  • ID: Bld smear, PCR.

  • TX: Diminazene injections, vector control(prevention), genetics

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<p><span>Vit K Deficiency</span></p>

Vit K Deficiency

  • MOA: diet issues, microbial rumen disruption, dicumarol poisoning, rodenticides!! (warfarin, brodifacoum), moldy sweet clover

  • CS: Hemorrhage, Weakness, Pallor

  • ID: clotting profile w/ prolonged PT+PTT

    • loss of clotting factors (factor II, VII, IX and X, proteins C, S and Z)

  • TX: Vit K1, Blood transfusion

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Lameness

  • Location: lateral claw, hind limb > forelimb

  • DX: sole ulceration, hoof overgrowth, interdigital hyperplasia, digital dermatitis

  • Scoring:

    • 1 = sound

    • 2 = uneven gait

    • 3 = obvious lameness

    • 4 = difficulty turning

    • 5 = extreme difficulty rising & non-weight bearing

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<p><span>Anesthesia of the Lower Limb (Bier Block)</span></p>

Anesthesia of the Lower Limb (Bier Block)

  • Tourniquet

  • Lidocaine

  • Adequate analgesia for 1 hour

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<p><span>Foot Rot (Interdigital dermatitis) </span></p>

Foot Rot (Interdigital dermatitis)

  • # 1 disease in food animals

  • MOA: Trauma, wet/muddy enviro, bacti

    • Fusobacterium necrophorum

    • Bacteroides melaninogenicus

  • CS: Acute lameness, foul odor, swollen tissues between toes - wet seasons

    • sudden 3-5 lameness score

  • TX: clean, debride, antibiotics, NSAIDs, farrier work, soaks, dry enviro, ZiSO4 under bandage

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<p><span>Digital Dermatitis</span></p>

Digital Dermatitis

  • AKA: Hairy heel warts, Papillomatous DD, strawberry foot, verrucous dermatitis, digital warts

  • MOA: wet/muddy enviro, bacti, older heifers

    • Treponema spp.

  • CS: Chronic lameness, lesions above interdigital cleft

  • TX: ELDU Oxytetracycline/SA under bandage, foot bath, dry enviro, Vax

    • not curable

    • Regular foot baths

    • WASH feet

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Footbath Guidelines

  • Frequency: 1–5 days/week 

  • Change solution after 150–200 cows pass through

  • Design:

    • Pre footbath: gross contaminants

    • Bath: wide and long, 5’ of solution, in alleys

  • Solutions: Formalin (pH 3), Copper sulfate, Zinc sulfate

    • Avoid Antibiotics

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<p><span>Acute Laminitis (Founder)</span></p>

Acute Laminitis (Founder)

  • MOA: sensitive laminae inflam

    • rumen acidosis, peripartum metabolic stress

  • CS: Acute lameness, "Cross-legged" stance, chronic hoof deformities

  • Prognosis: Increased risk of white line, ulcers, abscesses, false sole

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<p><span>White Line Disease</span></p>

White Line Disease

  • MOA: Separation of the sole + hoof wall

    • sequelae of laminitis

  • CS: Acute lameness of outer claw (hindlimb) or medial claw (forelimb)

  • TX: hoof trim, debride, oxytetracycline, bandage, wooden block on healthy claw, NSAIDs, dry enviro

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<p><span>Sole Ulcer (Pododermatitis Circumscripta)</span></p>

Sole Ulcer (Pododermatitis Circumscripta)

  • MOA: Subclinical laminitis and rumen acidosis

  • CS: lamness, leasion of lateral hind claws

  • TX: remove sole, CuSO4 under bandage, hoof block on sound leg

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<p><span>Interdigital Fibroma</span></p>

Interdigital Fibroma

  • MOA: Hypertrophy of interdigital space skin

    • (dairy) late lactation, Herford bulls

  • CS: Chronic skin irritation, lameness

  • TX: SX, wire stabilization

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<p>Hoof cracks </p>

Hoof cracks

  • Vertical (Sand Cracks)

    • CS: crack originating @ hairline

    • TX: trim, suture with wires, apply acrylic, apply wooden block

  • Horizontal (Thimbles)

    • MOA: disruption of hoof growth

      • Laminitis, Rumen acidosis, dry enviro

    • CS: crack parallel to coronary band, severe lameness

    • TX: trim, remove affected horn

<ul><li><p><span style="color: #000000"><strong>Vertical (Sand Cracks)</strong></span></p><ul><li><p><span style="color: green"><strong>CS: </strong></span><span>crack originating @ hairline</span></p></li><li><p><span style="color: green"><strong>TX:</strong></span><span> trim, suture with wires, apply acrylic, apply wooden block</span></p></li></ul></li><li><p><span><strong>Horizontal (Thimbles)</strong></span></p><ul><li><p><span style="color: green"><strong>MOA:</strong></span><span> disruption of hoof <u>growth</u></span></p><ul><li><p><span>Laminitis, Rumen acidosis, dry enviro</span></p></li></ul></li><li><p><span style="color: green"><strong>CS:</strong></span><span> crack parallel to coronary band, severe lameness</span></p></li><li><p><span style="color: green"><strong>TX: </strong></span><span>trim, remove affected horn</span></p></li></ul></li></ul><p></p>
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<p><span>Corkscrew Claw</span></p>

Corkscrew Claw

  • MOA: older cows, heritable

  • CS: twist of lateral claws of hind leg

  • TX: cull, frequent trims

    • No Cure

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<p><span>Pickup Bumper Syndrome</span></p>

Pickup Bumper Syndrome

  • MOA: Gastrocnemius m. rupture 

    • trama

  • CS: severe lameness, swelling

    • Swelling in the affected area, "dropped hock“

  • TX: rest, bandage, splint, NSAIDs

    • Poor prognosis

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<p><span>Blackleg (Clostridium chauvoei)</span></p>

Blackleg (Clostridium chauvoei)

  • MOA: ingested bacti

  • CS: sudden death in healthy animals, acute severe lameness, crepitant muscle swellings

    ID: gas-filled swellings, dark muscles/emphysema

  • TX: vax

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Malignant Edema (Clostridium septicum)

  • MOA: Wounds from castration, docking, parturition, shearing, fighting

  • CS: Depression, fever, anorexia, sudden death, edematous, dark, cold swellings

  • TX: high-dose antibiotics, NSAIDs, IV fluids, wound debridement, vax, wound hygiene

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<p><span>Contracted Tendons</span></p>

Contracted Tendons

  • MOA: young

  • TX: splint, tenotomy of SDFT, DDFT and suspensory lig.

    • Good prognosis

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<p><span>Arthrogryposis and Acorn Calves</span></p>

Arthrogryposis and Acorn Calves

  • MOA: Genetic (Charolais), toxins (lupines @ 40-70d), intrauterine infection

  • CS: dystocia, severe contracted tendons

  • TX: cull

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<p><span>Spider Lamb Syndrome</span></p>

Spider Lamb Syndrome

  • AKA: Corkscrew lambs, Monkey lambs, Crooked lambs, Bent lambs

  • MOA: Hereditary chondrodysplasia in sheep

    • Suffolk, Suffolk crossbred, Hampshire

  • CS: Kyphosis, Scoliosis, Angular limb deformities

  • TX: Cull

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Myotonia Congenita in Goats

  • MOA: genetic mutation of Cl channels

    • Tennessee fainting goat <6w

  • CS: stiff/fall w/ stimulation, not painful, remains conscious,

  • ID: EMG, genetic testing

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Capture Myopathy

  • MOA: Stress-induced muscle damage

  • CS: Muscle stiffness, weakness, tachypnea, tachycardia, hyperthermia, sudden death

  • TX: IV fluids, NSAIDs, calm handling

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<p><span>Tarsal Cellulitis (Hygroma)</span></p>

Tarsal Cellulitis (Hygroma)

  • MOA: Repeated trauma or pressure on bony prominences

    • Welfare indicator in housed livestock

  • CS: Firm, fluid-filled swelling over lateral hock, not painful

  • TX: clean enviro, drain abscess, bedding

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Osteoarthritis (DJD)

  • MOA: Progressive joint degeneration

  • CS: Lameness, stiffness, joint swelling

  • ID: xray

  • TX: NSAIDs, PT, glucosamine, chondroitin, SX, avoid overcrowding

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Osteochondrosis

  • MOA: defective endochondral ossification in rapidly growing males

  • CS: Lameness, peri-articular swelling

  • ID: ‘cyst’ like lesion on X-ray

  • TX: NSAIDs, arthroscopy, arthrotomy

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Stifle Injuries in Cattle

  • MOA: Trauma

  • CS: upper hind-limb lameness, stifle joint effusion, pain, crepitus, patellar luxation

  • TX: confinement + prolonged NSAIDs, good footing

    • Guarded to poor prognosis

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<p><span>Septic Arthritis</span></p>

Septic Arthritis

  • Neonates

    • MOA: <1m old, FPT

    • CS: Hot, painful, swollen joints, Fever, depression

    • ID: Arthrocentesis, Xray

    • TX: Antibiotics, NSAIDs, joint lavage, Colostrum, hygiene, naval dip

      • Good prognosis unless FPT

  • Adult

    • MOA: trauma, sepsis, hematogenous 

    • CS: Lameness, joint swelling, pain, heat, fever, lethargy

    • ID: Arthrocentesis, Xray

    • TX: Antibiotics, NSAIDs, joint lavage,

      • Prognosis is Guarded 

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<p><span><strong>Joint Lavage</strong></span></p>

Joint Lavage

  • Use: septic arthritis

  • Steps: 1L of Sterile balanced polyionic solution pushed into joint space, through and through method

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<p><span>Sepsis of the Distal Interphalangeal Joint (DIP)</span></p>

Sepsis of the Distal Interphalangeal Joint (DIP)

  • MOA: Untreated/advanced foot rot/sole ulcer/white line/punctures

  • CS: Severe non-weight-bearing lameness

  • ID: Arthrocentesis, Xray

  • TX: euth, antibiotics, NSAIDs, SX

    • Joint arthrodesis: Aggressive ($$) tx for valuable/young

      • drill + lavage w/ wooden block on healthy foot

    • Digit amputation: Salvage tx for older/invaluable

      • immediate pain relief but breakdown over time

      • P3, PIP, DIP, sperate P1+P2

<ul><li><p><span style="color: green"><strong>MOA:</strong></span> Untreated/advanced foot rot/sole ulcer/white line/punctures</p></li><li><p><span style="color: green"><strong>CS: </strong></span>Severe non-weight-bearing lameness</p></li><li><p><span style="color: green"><strong>ID:</strong></span> Arthrocentesis, Xray</p></li><li><p><span style="color: green"><strong>TX:</strong></span> euth, antibiotics, NSAIDs, SX</p><ul><li><p><strong>Joint arthrodesis: </strong><u>Aggressive</u> ($$) tx for <u>valuable</u>/young </p><ul><li><p>drill + lavage w/ wooden block on healthy foot</p></li></ul></li><li><p><strong>Digit amputation: </strong><u>Salvage</u> tx for older/invaluable </p><ul><li><p>immediate pain relief but breakdown over time</p></li><li><p>P3, PIP, DIP, sperate P1+P2</p></li></ul></li></ul></li></ul><p></p>
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Fractures

  • Tx: good ortho patients!

    • Dynamic Compression Plating: Humerus, femur, tibia

      • not for heavy animals

    • Intramedullary Pinning: Humerus, femur, tibia

      • watch for implant migration, not for heavy animals

    • Transfixation Pin-Cast: comminuted/unstable fractures, proximal limb fractures

      • good for heavy animals

    • Thomas Splint-Cast: distal to the elbow or stifle

    • Short-limb Cast: distal to the carpus and tarsal joints

      • easy, cheap, common

    • Full limb cast: distal physis of the radius or distal physis of the tibia

    • Splint: distal to the carpus and tarsal joints, pediatrics, simple breaks

      • easy, cheap, common

  • Complications: Osteomyelitis, delayed healing, sequestration, lameness, compartment syndrome

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<p><span>Nose Ring</span></p>

Nose Ring

  • Why: control bulls

  • Use: self-piercing, non-rusting metal ring

  • Steps: 9 - 12m old, local analgesia, through the nasal septum about one inch from the tip of the nose

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<p><span>Dehorning/Disbudding cows</span></p>

Dehorning/Disbudding cows

  • Why: safety for cattle and staff, reduce carcuss bruising

  • When: Perform as early as possible

    • Buds not attached to the skull <2m of age

  • How:

    • Caustic chemicals: <1w of age

      • Paste: NaOH, KOH, or CaOH

      • Injectable: CaCl

    • Hot iron: <2m of age

      • Butane-powered, rechargeable, or corded for 5–10 sec

    • Barnes dehorner: 3m-1y

      • Remove 1–1.5 cm skin at base, control bld, remove bone frag

    • Keystone dehorner: adult

    • Horn tipping: adult

      • Removes distal 1/3 of horn w/ saw

    • Meds: w/ local block (Cornual or ring), NSAIDs.

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<p>Dehorning/Disbudding goats</p>

Dehorning/Disbudding goats

  • Why: safety

  • When: Perform as early as possible

  • How:

    • Hot iron: <2w of age

    • Meds: NSAIDs, tetanus antitoxin, ring/cornual block

  • Complications: Thermal meningitis, Scurs and ingrown horns

<ul><li><p><span style="color: green"><strong>Why:</strong></span> <u>safety</u> </p></li><li><p><span style="color: green"><strong>When:</strong></span> Perform as <u>early</u> as possible</p></li><li><p><span style="color: green"><strong>How:</strong></span></p><ul><li><p><strong>Hot iron: <u>&lt;2w of age</u></strong></p></li><li><p><strong>Meds: </strong>NSAIDs, tetanus antitoxin, ring/cornual&nbsp;block</p></li></ul></li><li><p><span style="color: green"><strong>Complications: </strong></span>Thermal meningitis, Scurs and ingrown horns</p></li></ul><p></p>
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Descenting Goats

  • Sedation: Gen anesthesia

  • Tool: cautery

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<p><span>Keratoconjuctivitis (pink eye)</span></p>

Keratoconjuctivitis (pink eye)

  • MOA: summer, flies

    • SR: Chlamydophila pecorum (#1), Mycoplasma

    • Cow: Moraxella bovis, Mycoplasma

      • Herefords + young @ risk

  • CS: Epiphora, hyperemia, mucopurulent discharge, keratitis, mastitis, polyarthritis, pleuropneumonia 

  • ID: cytology, IFA, culture

  • TX: Topical antibiotics, systemic oxytetracycline, NSAIDs, eye patch, Subconjunctival penicillin, vax

<ul><li><p><span style="color: green"><strong>MOA:</strong></span><span><strong> <u>summer, flies</u></strong></span></p><ul><li><p><span><strong><u>SR: Chlamydophila pecorum (#1), </u></strong><u>Mycoplasma</u></span></p></li><li><p><span><strong><u>Cow: Moraxella bovis,</u></strong> <u>Mycoplasma</u></span></p><ul><li><p><span>Herefords + young @ risk</span></p></li></ul></li></ul></li><li><p><span style="color: green"><strong>CS: </strong></span><span>Epiphora, hyperemia, mucopurulent discharge, keratitis, <strong>mastitis, polyarthritis, pleuropneumonia&nbsp;</strong></span></p></li><li><p><span style="color: green"><strong>ID</strong>: </span><span>cytology, IFA, culture</span></p></li><li><p><span style="color: green"><strong>TX: </strong></span><span>Topical <strong><u>antibiotics</u></strong>, <u>systemic oxytetracycline</u>, NSAIDs, <u>eye patch, Subconjunctival penicillin, </u><strong><u>vax</u></strong></span></p></li></ul><p></p>
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Ocular Squamous Cell Carcinoma (SCC)

  • MOA: Locally invasive tumor of limbus, third eyelid, upper/lower eyelid margins

    • sunlight, age, no pigment, Herefords, Simmentals, Holstein-Friesians

  • TX: cryosurgery, eyelid wedge resection, third eyelid resection, enucleation (Lg), culling (invasive)

    • high recurrence

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<p><span>Enucleation</span></p>

Enucleation

  • Why: Panophthalmitis, Intra-ocular neoplasia, Severe infectious bovine keratoconjunctivitis, Trauma of globe

  • Restraint: Standing or recumbent

  • Analgesia: xylazine, locals

  • Postop: Systemic antibiotics, NSAIDs, remove sutures

  • Complications: Incomplete removal of neoplastic tissue, hemorrhage, abscess formation

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<p><span>Papillomatosis (Fibropapillomas, “Warts”)</span></p>

Papillomatosis (Fibropapillomas, “Warts”)

  • MOA: BPV (#1), benign, self-limiting

    • 6-24m old, associated with skin trama

  • CS: cauliflower-like, flat, gray, rough, crusty on the head, neck, brisket, teats, eyelids

  • TX: Spontaneous, Sx, cauterized, crush, vax

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<p><span>Dermatophytosis (Ringworm)</span></p>

Dermatophytosis (Ringworm)

  • AKA: Club lamb fungus

  • MOA: Trichophyton verrucosum

    • zoonotic, contact, winter

  • TX: iodine solution, chlorine bleach, sunlight

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<p><span>Dermatophilosis (Rain rot; Rain Scald)</span></p>

Dermatophilosis (Rain rot; Rain Scald)

  • AKA: Streptothricosis, Lumpy wool

  • MOA: Dermatophilus congolensis, actinomycete

    • Moist enviro, zoonotic

  • CS: matted tufts of hair

  • ID: smear, diff-quick, railroad tracks or tramcar line 

  • TX: antibiotics, lime sulfur, keep dry

<ul><li><p><span style="color: green"><strong>AKA:</strong></span><span> Streptothricosis, Lumpy wool </span></p></li></ul><ul><li><p><span style="color: green"><strong>MOA: </strong></span><span><strong><u>Dermatophilus congolensis, actinomycete</u></strong></span></p><ul><li><p><span>Moist enviro, zoonotic </span></p></li></ul></li><li><p><span style="color: green"><strong>CS: </strong></span><span><strong><u>matted tufts of hair</u></strong></span></p></li><li><p><span style="color: green"><strong>ID: </strong></span><span>smear, diff-quick, <strong><u>railroad tracks or tramcar line&nbsp;</u></strong></span></p></li><li><p><span style="color: green"><strong>TX: </strong></span><span>antibiotics, lime sulfur, keep dry</span></p></li></ul><p></p>
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<p><span>Urticaria and Angioedema</span></p>

Urticaria and Angioedema

  • MOA: Type 1 hypersensitivity rxn

    • bites, vax, milk allergy

  • CS: rapid hives, skin wheals, lg edema plaques

  • ID: rxn to tx

  • TX: Antihistamines, NSAIDs

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Photosensitization

  • MOA:

    • Primary: photodynamic agent is directly ingested, injected

      • Hypericin (St. John’s wort), Fagopyrin (buckwheat)

    • Congenital: abnormal pigment synthesis

      • Bovine erythropoietic protoporphyria and bovine erythropoietic porphyria

    • Secondary (#1): impaired hepatic excretion of phylloerythrin

      • pyrrolizidine alkaloids, Blue-green algae

  • Cs: erythema, edema, crusting, and necrosis of non-pigmented, hairless skin

  • ID: high SDH, GGT, ALP, bilirubin

  • TX: Remove from pasture, shade, NSAIDs, corticosteroids

    • poor prognosis

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<p><span>Lice</span></p>

Lice

  • CS: pruritus, restlessness, and excessive licking, anemia

  • TX: Organochlorine, organophosphurus, pyrethroid, Coumaphos, Diazinon and permethrin, Ivermectin (sucking lice but not biting)

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Ticks

  • MOA: Cattle fever tick (babesia-reportable), Dermacentor (anaplasmosis)

  • CS: Inflam, itching, and swelling, disease, anemia, death, secondary infections

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<p><span>Mange</span></p>

Mange

  • MOA: colder months, housed animals with close contact

    • Psoroptes ovis: Eradicated in sheep, found in cattle,highly pruritic

    • Psoroptes cuniculi: SA Ear mite

    • Scabies: Burrowing mite, severe pruritus

    • *Chorioptes bovis: "tail mange," "foot mange," "red mange“, #1 cause of cattle mange

    • *Demodex: non-pruritic, cigar-shaped mites

  • CS: skin irritation, hide damage, reduced weight gain

  • ID: deep skin scrape

  • TX: macrocyclic lactones, topical hot lime sulfur

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Obligatory or Primary Myiasis

  • MOA: Cochliomyia hominivorax, the New World screwworm

    • must live on living tissue for life cycle

  • TX: lindane, ronnel, nitenpyram

    • Reportable disease

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<p><span>Facultative or Cutaneous Myiasis (Flystrike, Blow fly strike or Maggots)</span></p>

Facultative or Cutaneous Myiasis (Flystrike, Blow fly strike or Maggots)

  • MOA: fly stike, contaminated wounds, sheep

    • tail docking, sx

  • CS: begin feeding on the sheep's skin and flesh, causing irritation, tissue damage, secondary bacti infections

  • TX: Shear, ivermectin, organophosphates, wound care, Crutching

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<p><span>Hypodermiasis (Warbles, Grubs)</span></p>

Hypodermiasis (Warbles, Grubs)

  • MOA:

    • H. lineatum: migrate to caudal esophagus submucosa

    • H. bovis: migrate to epidural fat of thoracolumbar vertebrae

  • CS: bloat, paralysis, salivation, anaphylaxis

  • TX: ivermectin, moxidectin, OP

    • July and Oct

    • watch for anaphalaxis

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<p><span>Sheep ked</span></p>

Sheep ked

  • MOA: direct contact, fall/winter, long wool

    • zoonotic

  • CS: Loss of condition, anemia, irritation, biting,  rubbing, damaged skin and poor fleece quality

  • ID: wingless flies

  • TX: ivermectin, moxidectin, OP