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What is obstructed in a PE?
One or more branches of the pulmonary artery

Greatest risk factor for a PE
presence of a DVT
Major predisposing factors for the development of DVT
Virchow’s Triad
Venous Stasis
Vessel wall damage
Hypercoagulability
Most common cause of DVT
Prolonged Immobility
5 sources of PE
DVT
Fat
Air
Amniotic fluid
Tumor
Causes of Hypercoagulability
Cancer
Oral contraceptives (birth control)
Dehydration
Hemoconcentration
Sickle Cell
Polycythemia
Abrupt DC of anticoagulant
Causes of Venous Stasis
Prolonged bedrest/immobility
Obesity
Burn
Pregnancy
Post-Op
Causes of endothelial damage to vessels
Trauma
IV drugs
Atherosclerosis
What may put elderly patients at risk for a PE?
Knee/Hip replacement surgery → Limited mobility due to pain
What is hemodynamic instability?
the blood clot is so severe it causes the circulatory system to fail, leading to dangerously low blood pressure (hypotension) or shock, often because the right side of the heart can't pump blood effectively through the blocked lungs