Donor Selection and Testing

How long must donor records be kept?

5-10 years or indefinitely depending on the case

What is done to screen a donor before their blood is even donated?

- physical exam
- serologic blood testing
- registration
- medical history questions

What info is needed for registering a donor?

- name and age (confirm ID and age w/ license)
- date/time of collection
- address and phone number
- gender

Informed Consent

risk of procedure: pass out, hematoma, paresthesia, infection
able to understand explanation and tests that will be done

What are the weight, temperature, and BP requirements for a donor?

weight: 110 lbs
temp: < 37.5 or 99.5
pulse:50-100
BP: < 180/100

What H/H values are necessary for female/male donors?

females: > 12.5 and 38%
males: > 13 and 39%
(self: 11 and 33% w/ doctors approval)

What are the donation intervals for whole blood and apheresis units?

whole blood: 8 weeks
apheresis: 16 weeks

Temporary deferral

unable to donate for a limited time

Indefinite deferral

unable to donate for an unspecified period of time due to the current regulatory requirements (can change)

Permanent deferral

Prospective donor will never be eligible to donate blood for someone else

What condition can lead to a deferral period of 2-3 days?

NSAIDs, aspirin, interval btwn autologous donations

2 week/14 day deferral period

live attenuated or bacterial vaccines (measles, mumps, polio, yellow fever)
taken plavix or taclid after last dose

4 week deferral period

Rubella vaccine (German measles)

6 week deferral period

after birth (pregnancy)

12 month deferral period (hella)

syphilis, gono, transplant, bite, HBIG, tattoo, blood exposure/needlestick, sex w/ HIV + person, malaria, leishmania, piercing, transfusion during pregnancy, juvy, sex w/ hemophiliac, sex w/ 2 males

14-21 day deferral period

after smallpox vaccine (when scab falls off)

For directed donations, if the patient is related to the donor what must be done?

unit must be irradiated

What can be made from a whole blood collection?

packed RBCs, plasma, plts, cryoprecipitate

What types of apheresis are there?

RBC, stem cell, plts, plasma, granulocytes

What storage temps are used for whole blood, RBCs, plasma, plts, and granulocytes?

whole blood: 1-6
RBCs: 1-6, frozen < -65 of -120
Plasma: < - 18 frozen, 1-6 thawed
Plts and granulocytes: 20 -24

What units need special labels?

directed donor and autologous donor (can't be used on someone else)

What preservatives are used for adults and what is their storage time?

AS-1, 3, 5 (42 days)

What preservatives are used for kids and what is their storage time?

ACD, CPD, CP2D (21 days)
CPDA-1 (35 days)