Describe function of fat in the body (7)
Provided unlimited energy (storage)
insulates the body (temperature)
protection of body organs
Transport of fat soluble vitamins/nutrients
Hormone regulation (compound synthesis)
Used in nervous system (neurotransmission)
Part of cell membrane
Functions of fat in food
Flavor and aroma
Texture
Satiety
Carries fat soluble vitamins
Source of essential fatty acids
Triglycerides
Most common lipid found in food and body
Consists of glycerol and 3 fatty acids
Fatty acids
Classified based on degree to which the carbon and is saturated with hydrogen
Saturated
Mono saturated
Polysaturated
Fatty acids is..
__ if it contains no carbon double bond
__ if it has only one carbon double bond
__ if it contains two or more carbon double bonds
Cis formation
When hydrogens on an unsaturated fatty acid lie on the same side of the carbon double bond
Trans form
When hydrogen on both carbons forming the double bond lie on the opposite sides of the bond
Lipid digestion
Mouth:
Stomach:
Pancreas:
Liver:
Small intestine:
Mouth: salivary lipase
Stomach: gastric lipase, stomach acids
Pancreas: secretes pancreatic lipase and other enzymes
Liver: secretes bile to emulsify fat in chyme
Small intestine: site of most fat digestion and absorption
AMDR recommendation of fat
20-35% of calories
Linoleic acid
Linolenic acid
Essential fatty acids:
Omega 6
Omega 3
Saturated fatty acids foods
Coconut oil, palm oil, bacon butter and lard
Monounsaturated fatty acid foods
Avocado, olive oil, canola oil, peanut butter
Polyunsaturated fatty acid foods
Salmon, nuts, plant sources, sunflower oil, soybean oil
Cholesterol foods
Only animal product (dairy, eggs, meat)
Omega 3 fatty acid foods
Cold water fish, canola oil, soybean oil, flaxseed oil
Omega 6 fatty acid foods
Corn, mayonnaise, sunflower oil
EPA and DHA and ALA
Types of omega 3 (linolenic) acid
EPA and DHA food sources
Cold water fish
ALA food sources
Flax, canola, soy, walnuts
Coconut oil is __ is saturated fatty acids than butter and beef fat
Higher
Omega 3 benefits in body (4)
Decrease blood clotting
Decrease circulation of triglycerides
Decrease swelling
Lower blood pressure
Affects of omega 6 on body (2)
Increase inflammation
Increase clotting
Atherosclerosis
Increase in fat in artery wall
Oxidized LDL from plaque
Narrowed arteries are at risk for clots
Components of an anti atherosclerosis lifestyle
Physically active
Good diet, low in saturated and trans fat
Stop smoking
Increase risk for cardiovascular disease
Age > 65
Diabetes
Smoking
High saturated fat diet
Cholesterol
Sterols
Phospholipids
In all cell membranes, 2 fatty acids and 1 phosphate
Chylomicrons
Lipoprotein produced in the small intestine
Takes long chain fatty acids and groups them together
Carries fat from the small intestine to the cells
VLDL
Lipoprotein that carries lipids made by the liver to cells
Broken down by lipase, broken down into glycerol and fatty acids
HDL
Roams the bloodstream, picking up cholesterol and donates back to the liver to be excreted
Nitrogen
Proteins contains __ which are the building blocks of protein
Which part of the chemical structure differentiates one amino acid from another?
The side chain
4 steps of protein synthesis
DNA code is copied from cell nucleus. Transferred by mRNA strand into cytoplasm
mRNA strand carries DNA to ribosomes, where protein translation occurs
tRNA (transfer RNA) adds amino acids from amino pool, to mRNA instructions, for a polypeptide chain
Polypeptide chain twists and folds into a 3D structure of the intended protein
__ amino acids in body
__ essential amino acids
20
9
Protein digestion
Stomach:
Pancreas:
Liver:
Small intestine:
Large intestine:
Stomach: pepsin and acid work to digest protein
Pancreas: organ releases trypsin to digest protein
Liver: Hypatia portal vein delivers absorbed amino acids and then to bloodstream
Small intestine: final digestion of amino acids to single amino acids
Large intestine: very little protein is present
How are amino acids used in cells?
They are converted to non essential amino acids
The nitrogen from amino acid breakdown is converted to __
Urea
Metabolism
Uses protein as energy
Function of proteins in the body
Synthesis of enzymes and hormones
Forms structure of bones and muscle
Immunity
Blood clotting
Transportation
What does the body do with extra protein?
Nitrogen is dismantled — and excreted through urine in kidney
Remaining amino acids are used for energy (glucose)
Stored as fat
Positive protein balance
Pregnancy, growing child, illness, athlete
Negative protein balance
Inadequate protein and caloric intake
Fevers, burns, infections
Protein loss (kidney disease)
Loss of body tissue
Protein equilibrium
Healthy adult meeting nutrient needs
— caloric and protein needs
Edema
Blood protein levels fall and fluid shifts into extra cellular spaces
Swollen limb and stomach
High quality proteins
Meat, fish, dairy, eggs
Low quality proteins
Vegetables and grains
Medium quality proteins
Nuts and legumes and seeds
Complimentary proteins
2 incomplete proteins, to make 1 complete protein
Rice and beans
MyPlate recommendations for protein
__ dairy
__ protein
__ grains
__ fruits
__ vegetables
8-10 g/cup dairy
7 g/oz protein
2-3 g/oz grains
1 g/c fruit
2-3 g/c vegetables
AMDR for total protein intake
10 - 35% of total calories
RDA for protein
0.8 g per kg body weight
__ kg = 1 lb
2.2 kg = 1 lb
When protein is converted to glucose or fat, nitrogen is eliminated from the body via __
Kidneys
Forms of protein calorie malnutrition (2)
Kwashiorkor and marasmus
Kwashiorkor characteristics (3)
Children go from breast milk to high starch and low protein diet
Fatty liver
Deficiency in protein, not necessarily calories
Rapid development
Marasmus characteristics (3)
Deficiency in protein and calories in diet
Develops gradually
Skin and bone appearance
Consequences of protein calorie malnutrition
Malnutrition
Slow growth
Impaired immunity
Impaired nutrient absorption
Impaired brain and kidney function
What is a potential problem with consuming individual amino acid supplements?
Impaired absorption of other amino acids
Nutrigenomics
Examines how foods impact health through its interactions with genes
Nutrigenetics
Effects of genes on nutritional health
Ex. Responsiveness to dietary modifications
Epigenetics
The study of heritable changes in gene function that are independent of DNA sequence
Vegan diets have a lack of __ (6)
Protein
Vitamin B12
Zinc
Iron
Calcium
Omega 3 fats
Vitamin D
Basal Metabolic Rate
Energy expenditure, especially breathing (60-75%)
Factors that decrease BMR
Insufficient thyroid hormone production
Aging
Less body surface area
Very low calorie diet
Factors that increase BMR
Pregnancy
Stress, caffeine
More body surface area
Illness
High body fat %
Basal metabolism
Supports body functions — heart lungs brain
Adaptive thermogenesis
Body’s adjustment to energy expenditure related to changes in environment such as extreme cold
Thermic effect of food
Energy used to digest food, increase in metabolic rate after eating
Underweight:
Normal:
Overweight:
Obese:
Underweight: <18.5 kg
Normal: 18.5-24.9 kg
Overweight: 25 - 29.5 kg
Obese: >30 kg
Waist circumference (central obesity spot)
Measurement to be considered obese:
Female: >30 in
Male: >40
Risks for BMI weight
Low:
Moderate:
High:
Low: underweight
Moderate: normal weight
High: obese
Sleep apnea
Excess weight puts pressure on pharynx and lungs
Heart disease
Excess weight and enlarged adipose cells increase LDL
Cholesterol, triglycerides, blood clotting, and inflammation
Gallstone formation
High fat and cholesterol diet increases cholesterol in bile
Liver damage
High fat diet lead to excessive fat in liver erectile dysfunction in mend
Excess weight causes inflammation and reduced function of red blood cells
3 ways for successful weight loss
Modification of behaviors
Decreased calorie intake
Increased physical activity
Factors of healthy weight loss
Long term
Variety of food groups
Equal to about one pound a week
In amino acid breakdown, what part of the amino acid is used for energy?
Carbon skeleton
How can a vegan get more B12 vitamin?
Drink fortified soy milk, fortified ready to go cereal, or a B12 supplement
Visceral fat
Excess at in the abdomen
Higher likelihood of risk of disease
Basal metabolism examples
Hormone secretion
Beating of heart
Respiration
Bile
Emulsifies fat, produced in the liver, helps with fat digestion
Lipoprotein
Carries fat soluble compounds in the bloodstream
Mouth (fat)
Salivary lipase
Stomach (fat)
Gastric lipase
Stimulates liver to produce bile salts to emulsify fat
Small intestine (fat)
Pancreas is stimulated to release pancreatic lipase and fully break down triglycerides
Micelles are present
Fatty acids in fat digestion
Enter intestinal lining, then into blood
Long chain fatty acids in fat digestion
Packed into chlyomicrons
Chlyomicrons
Lipoproteins that transport lipids into tissues in body then lymphatic system then bloodstream
What do triglycerides break down into?
Glycerol
Monoglyceride
Fatty acids
What is responsible for lipid transportation? (4)
Lipoproteins IN LIVER
Chylomicrons, VLDL, LDL, HDL
VLDL
Transport cholesterol from liver to cells
Lipase breaks down into glycerol and fatty acids
LDL
Transport cholesterol for cell membranes
Risk of heart disease if levels are too high
Cholesterol
Produced in liver, stores energy
Helps with hormone production, propels bile, maintains stability of CELL MEMBRANE
Phospholipids
2 fatty acids and glycerol
Lecithin
Forms cell membrane
Lecithin
Emulsifier in fat
Stomach (protein)
Pepsin, denatures protein (unravels protein for easier digestion)
Starts to break peptide bonds
Small intestine (protein)
Partially digested protein triggers CCK
Single amino acid absorption in intestinal walls
CCK
Cholecystokinin
Triggers pancreas to release trypsin and split proteins