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Unit five- Cerebrovascular History and Physical
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What are the 4 vessels that supply blood to the Brain?
The two Internal Carotid Arteries (right and left)
The two Vertebral Arteries (right and left)
What are we doing with a cerebrovascular ultrasound?
We differentiate normal from diseased, see if it is acute or needs intervention, and identify collateral pathways
What 3 things do we do in a cerebrovascular exam?
detect, localize, and quantify cerebral embolism
What are some things we are looking for on a cerebrovascular ultrasound?
Predict stroke risk
Subclavian steal
Monitor autoregulation
Intracranial steal
Monitor vasospasms
Intracranial pressure
The 2 Vertebral Arteries
Posterior Circulation
The 2 Internal Carotid Arteries
Anterior Circulation
How to we predict stroke risk?
Carotid Exams
STROKES: Currently, the ____ leading cause of death in the United States
5th
STROKES: Approximately _______ new stroke occur yearly in the United States
610,000
STROKES: Leading cause of _________ __________
Permanent Disability
STROKES: BRAIN: ____ of the body weight, received _____ of the cardiac output and consumes _____) of body’s Oxygen supply in basal, resting state
2%; 15%; 20%
Causes of strokes:
Cardiogenic (caused by the heart)
Large Vessel Atherothrombotic
Lacunar
Other
Unknown
May be caused by a narrowing of the vessel OR may be hemorrhagic
What percentage of strokes are caused by Cardiogenic?
35%
What percentage of strokes are cause by Large Vessel Atherothrombotic?
30%
What percentage of strokes are caused by Other?
10%
What percentage of strokes caused by Unknown?
15%
What percentage of strokes caused by Lacunar?
10%
Lacunar:
When an artery that supplies blood to the DEEPER portions of the brain becomes blocked (thalamus, basal ganglia, or pons…)
Risk Factors of Strokes:
Age
Gender
Hypertension
Tobacco Use
Diabetes
Obesity
High Cholesterol
Sedentary Lifestyle
PVD
CAD
Family or personal history
Stroke and symptom classifications:
Asymptomatic
Transient Ischemic Attack (TIA)
Cerebrovascular Accident (CVA)
Reversible Ischemic Neurological Deficit (RIND)
TIA
Transient Ischemic Attack
CVA
Cerebrovascular Accident
RIND
Reversible Ischemic Neurological Deficit
Asymptomatic Stroke:
Without symptoms
Patient presents with a BRUIT
Asymptomatic Stroke: Patient presents with a BRUIT:
Noise heard during auscultation
Caused by turbulent blood flow that set up vibratory response in the tissue
“Cervical Bruit” (C.B.)
C.B. will often be an indication for a ___________________
Cerebrovascular Exam (Carotid Duplex)
Cervical Bruits ar caused by:
Stenosis in the CCA, ICA, or ECA
Tortuous Carotid Vessel or Vessels
Aortic Valve Stenosis
(occlusion)
CERVICAL BRUIT: You cannot tell what is causing the bruit without during further tests:
Carotid Duplex
Echocardiogram
C.B.: Cannot distinguish if a stenosis is in ___, ____, or ____
CCA, ICA, or ECA
BRUIT CHARACTERISTICS:
Location
Intensity
Duration
Frequency
Quality
Bruit Characteristics: Location
Bell of stethoscope at Innominate, Subclavian, CCA Bifurcation, Vertebral
Bruit Characteristics: Intensity
“Loudness”
Increases between no stenosis and moderate stenosis
Decreases between moderate range and occlusion
Many bruits disappear when stenosis is > 90% diameter reduction
Bruit Characteristics: Duration
Increases with increasing degree of stenosis
Short systolic, systolic, or pan-systolic/continuous
Bruit Characteristics: Frequency
“Pitch”
Increases with degree of stenosis
Bruit Characteristics: Quality
Soft blowing, harsh blowing, coarse, gruff, moaning, whining, seagull
TYPES OF STROKES:
TIA
CVA
RIND
Characteristics of a transient ischemic attack (TIA)
brief, fleeting
lasts only 1-30 mins
symptoms often ignored
transient neurological deficit that lasts <24 hours
What is another name for a TIA?
Mini stroke
Iif a mini stroke is ignored, what percent of patients will go on to a full stroke within 5 years?
30-35%
What causes a TIA?
Typically embolic in nature from the heart or due to ulcerative plaque in the ICA
What are the characteristics of a CVA?
STROKE
Lasts >24 hours
Permanent damage
Symptoms persist
Symptoms may improve, but never completely resolve
What is an Acute CVA?
symptoms are sudden, considered unstable
What is a stroke in Evolution CVA?
Symptoms come and go, crescendo
What is a Completed stroke CVA?
No progression OR resolution of symptoms
What is another name for CVA?
Stroke
What are the characteristics of a RIND?
>24 hours but resolves in less than 3 weeks
Brain tissue is damages but recovers completely
Between TIA and CVA
What are the etiologies of a stroke?
Atherosclerosis
Embolus from heart
HTN
Dissection
Prothrombotic state
Vasospasm
Atherosclerosis
Intimal disruption or lumen stenosis
What is the most common cause for atherosclerosis?
Arteriosclerosis
What age is atherosclerosis most common in?
> 45 years old
What percent of patients with atherosclerotic disease had a TIA prior to stroke?
60%
Which of the following is NOT true regarding atherosclerosis?
-Atherosclerosis starts within the intima
-Atherosclerosis typically occurs at bifurcations
-Atherosclerosis is a red blood cell disease
-Atherosclerosis is a generalized disease
-Intimal disease may begin in adolescence
-Atherosclerosis is most common cause of carotid artery occlusion
Atherosclerosis is a red blood cell disease
What is the second leading cause of stroke?
Embolus from the heart
Embolus from the heart
May affect any age patient
Rhythm abnormalities
Atrial Fibrillation
Damaged endocardium
LA or LV
Valve damage
Mitral or Aortic
What is the number 1 leading cause of stroke?
HTN
Why is hypertension the leading cause of a stroke?
Narrows blood vessels with super high velocities, causing them to burst
Arteriolar sclerosis or lipohyalinosis results in what?
The formation of small localized areas of infarction called lacuna
What are Lacunar Strokes?
Small, localized areas of brain damage caused by blockages of the SMALL Blood Vessels
Liop:
“Condition that affects the small blood vessels in the brain (CEREBRAL ARTERIES)– accumulation of luipds and protein like sybstances in the vessel walls, which leads to thickening and narrowing
HTN: Injures small vessels of the Brain and Kidneys is called what?
arteriolar sclerosis or lipohyalinosis
What is a Dissection?
Hemorrhage and thrombus formation within arterial walls; also causes narrowing of the lumen
A Dissection is a tear between the:
Intima and Media
Media and Adventitia
What causes Dissections?
Trauma
HTN
Marfan's Syndrome
Dissections located in the following areas may head to stroke:
Aorta (ascending → arch)
Carotid Arteries: CCA Origin or mid-distal ICA
Vertebral Arteries
What is a Prothrombotic State?
Increased state of coagulability/ hypercoagulability/ abnormality in coagulation
What is a Vasospasm?
Sudden constriction of a blood vessel, reducing its diameter and flow rate
What is a Vasospasm usually associated with?
Subarchnoid Hemorrhage
When do spasms start to occur with a vasospasm?
3rd day of hemorrhage
Degree of spasm depends on:
Amount of blood present around the arteries and time
What arteries are the Anterior Circulation of the brain?
ICA, MCA, ACA
What arteries are the Posterior Circulation?
Vertebral Arteries, Basilar Artery, PCA
Disease in the Innominate and CCA also lead to:
Anterior Circulation symptoms
Anterior Circulation (AC)
Hemispheric
Anterior Circulation:
Left ICA feeds ____ Ophthalmic Artery
Right ICA feeds ____ Ophthalmic Artery
Left, Right
Characteristics of Anterior Circulation symptoms:
left hemisphere side of brain = right side of body symptoms
right hemisphere side of brain = left side of body symptoms
Bodily signs and symptoms originate from the ______ side of the body
Opposite
Signs and symptoms of the EYE originate from the ____ side
Same
Left eye symptoms occur from which hemisphere?
Left
Right eye symptoms occur from which hemisphere?
Right
What is transient monocular blindness (amaurosis fugax AF)? (AC)
Temporary partial or complete loss of vision in one eye
What does TMB/AF implicate?
Carotid system on same side as visual disturbance
What is transient monocular blindness (AF) caused by?
Hollenhorst plaques
What circulation is transient monocular blindness (AF)?
Anterior
Hollenhorst Plaques
Atheromatous plaques that have lodged into the retinal vessels; causes dark spots → embolic Event
What is Aphasia or Dysphasia?
Absent or impaired ability to communicate either through speech, writing or signs
What does Aphasia or Dysphasia implicate?
Implicates the carotid system perfusing the dominant hemisphere
What are the different types of Aphasia?
Auditory
Visual
Sensory
Motor
Global
If a right handed person has a aphasia, what hemisphere is affected?
Left
If a left-handed person is affected by aphasia, which hemisphere is likely affected?
Either
What is Auditory Aphasia?
Word deafness/inability to understand the spoken word
What is Visual Aphasia?
Word blindness/Inability to understand the written word
What is Sensory Aphasia?
Combination or auditory and visual; will not understand spoken or written word
What is Motor Aphasia (Expressive aphasia brocas)?
Patients know what they want to say, but cannot get the words out; unable to coordinate the muscles controlling speech
What is Global Aphasia?
“Total Aphasia;” Involves ALL form of communication
Is Paresthesia due to the anterior or posterior circulation?
Anterior Circulation
What is Paresthesia? (AC)
Numbness, prickling, tingling, or heightened sensitivity
Paresthesia: Monoparesthesia/Hemiparesthesia
One sided paresthesia
Left side symptoms implicate right carotid system disease and visa versa
Is Paresis anterior or posterior circulation?
Anterior
Paresis (AC)
Paralysis
Monoparesis/Hemiparesis
One sided paresthesia
Left side symptoms implicate right carotid system disease and visa versa
What are the main Anterior Circulation symptoms?
MCA lesions
ACA lesions