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What is the purpose of the lungs?
Breathe in oxygen and absorb oxygen in blood via gas transfer
What is alveolar ventilation?
Breathe in oxygen
What is pulmonary perfusion?
absorb oxygen in blood
What does ventilation-perfusion matching mean?
When alveolar ventilation and pulmonary perfusion are matching.
What is the respiratory rate at birth?
44 breaths per minute
What is the respiratory rate at age 2?
26 breaths per minute
What is the respiratory rate for adults 18+?
12-20 breaths per minute
What is the respiratory rate for seniors?
up to 28 breaths per minute
What is the respiratory rate for adults 18+ during exercise?
40-60 breaths per minute
When are PFTs conducted?
In known or suspected lung diseases, when lung symptoms are experienced chronically
In case of continual workplace hazard exposure
To evaluate how well breathing treatments are managing disease and to check eligibility for disability and/or surgery
What to PFTs determine?
If observed lung function constitutes obstructive or restrictive lung processes.
Obstructive lung disease are…
conditions where air cannot be EXHALED as easily
What are examples of obstructive lung diseases?
Asthma
COPD
Cystic Fibrosis
Obstructive sleep apnea
When is an obstructive lung disease defined?
FEV1/FVC = <70% of expected post-bronchodilator
Restrictive lung diseases are….
conditions where air cannot be INHALED as easily
What is an example of restrictive lung disease?
Pulmonary Fibrosis
When are restrictive lung diseases defined?
When TLC = <80% of expected
What information do PFTs match on to determine if the function is within the expected limits?
Age
Height
Sex (Gender)
Race
What is tidal volume? (Vt)
Lung volume inhaled and exhaled during normal breathing
What is vital capacity? (VC)
Total volume of air that can be exhaled
What is forced vital capacity? (FVC)
Total volume of air that can be forcefully exhaled
What is forced expiratory volume in 1 second? (FEV1)
Total volume of air that can be forcefully exhaled in 1 second
What is total lung capacity? (TLC)
Total volume of air the lungs can hold (VC + RV)
What is residual volume? (RV)
Total volume of air left in the lungs after a full exhalation (TLC - VC)
What amount of adults patients without an obstructive lung disease exhale in 1 second?
80% or more
Spirometry can measure what?
FEV1
FVC
Forced expiratory flow (FEF)
What can spirometry not measure?
RV or TLC
What can measure TLC via RV?
Body plethysmography
What does low DLCO mean?
Low transfer of gas from the lungs into the blood
COPD is associated with
a low DLCO due to alveolar destruction
Asthma is associated with
a high DLCO due to more air in the lungs (trapped via obstruction)
What cardiac component is COPD associated with?
Defective capillary changes
What cardiac component is asthma associated with?
More capillary flow due to increased cardiac output
When is the reversal of an obstruction considered successful using a beta agonist? (albuterol)
When 2 conditions are met
1) an increase in FEV1 of > 12%
2) an increase of FEV1 by 200 mL or more
Peak flow meters are backed by expert opinion in asthma because
their data is limited and inconsistent
What is the measurement of the Green Zone on a peak flow meter?
80-100%
What is the measurement of the Yellow Zone for a peak flow meter?
50-80%
What is the measurement of the Red Zone in a peak flow meter?
<50%
What does pulse oximetry measure?
Oxygen saturation in blood
What factors can affect a pulse oximetry reading?
Poor circulation
Thick nail
Nail polish
Dark skin
What is an alternate option for pulse oximetry besides the finger?
A probe placed on ear lobe, nose, toe, or forehead
(None are as good as the finger)
What can’t pulse oximetry differentiate between?
Oxygen & Carbon Monoxide
When was the first FDA approved pulse ox approved for OTC use?
2024
What is the name of the guidelines for asthma?
GINA
What is the name of the guidelines for COPD?
GOLD