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Is sleep different across species?
YES
What sleeps unilaterally so they can continue moving?
cetaceans
What headset monitors neural activity during sleep?
EEG
What headset monitors muscle tone during sleep?
EMG
What headset monitors eye-movement during sleep?
EOG
What waves signify wakefullness and alertness?
Beta Waves
What waves signify restfulness and decreased neural activity?
Alpha Waves
What is the first stage of sleep that transitions between sleep and wakefulness?
Theta Activity
What stage of sleep is characterized by irregular firing patterns and sleep spindles?
Sleep Stage Two
What sleep stage if characterized by high amplitude, low frequency waves
Stage Three Sleep (deep sleep or slow wave sleep)W
In what sleep stage does delta activity increase to 50%
Stage Four Sleep
What is the fifth sleep stage?
REM
What waves is REM sleep comprised of?
Beta and Theta waves
Do we have muscle tone during REM sleep?
NOOOOOO (TOTAL PARALYSIS)
What sleep stage is associated with sexual arrousal?
REM
Being woken up from which sleep stages will leave you groggy without reports of dreams?
Stages 3 or 4
Being woken up in which stage ensures you will remember the dream you were having?
REM (5)
During which stage of sleep do night terrors occur?
slow-wave sleep
What sleep disorder reportedly affects 25% of the population?
Insomnia
What is one of the main causes of insomnia?
Sleep apnea
What categories do sleep medicines fall under?
-Antihistamines
-Antiglutamatergics
-GABA agonists
-Adenosine agonists
What is likely the cause of Narcolepsy?
a mutated gene for Orexin
What medication is used to treat Narcolepsy?
Modafinil
What is cataplexy?
complete muscle weakness
What is sleep paralysis?
brief inability to move just before falling asleep or just after waking (after physical exertion)
Why does REM sleep disorder occur?
The motor neurons do not get paralyzed
What sleep disorder is a neurodegenerative one?
REM Sleep Disorder
What are some slow-wave sleep issues?
-Bedwetting
-Sleep Talking
-Night Terrors
-Sleep-related eating disorders
Why do we have slow-wave sleep?
neural rest
Why do we have slow-wave sleep and REM?
memory consolidation
Why do we have REM sleep?
promotes neurodevelopment
What does sleep deprivation impair?
the brain and cognition
Are long periods without sleep ever made up entirely?
NOPE
What is the product of cellular oxidative stress?
Free radicals
What is a fatal sleep disorder?
Fatal Familial Insomnia
What increases the prevalence of slow-wave sleep?
mental exercises
What is explicit memory?
memory for people, places, episodes
Whaaaat is implicit memory?
memory for procedures and activities
What does the body keep track of for sleep?
sleep debt
What does the body promote during the day?
alertness
What does the body promote at night?
sleep
What is Adenosine?
a nucleoside neuromodulator
What neurotransmitters counteract sleep-promoters?
Acetylcholine
Norepinephrine
Serotonin
Histamine
Orexi
What are the two origins of cholinergic system?
1. Ponsreticular formation
2. Basal Forebrain
What is responsible for the neural desynchrony observed during certain stages of sleep and wakefulness
cholinergic activity
What are the NE pathways considered?
vigilance
Where are histamines located?
TMN of Hypothalamus
What is sleep controlled by?
Homeostasis, allostasis, and circadian rythms
What is known as our biological clocks?
circadian rhythms
What are circadian rhythms controlled by?
light, stimulus, internal clocks,
What are our internal clocks called?
zeitgerbers
What are long-acting rhythms?
seasonal rhythms
What secretes melatonin?
the pineal gland
How do you fix shift work/jet lag>
external cues to recalibrate rhythms