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what other two systems are closely tied to the CV system
respiratory and renal
what generates pressure to circulate blood
heart
what transports blood, regulates blood pressure, and exchanges
blood vessels
what are the 5 types of blood vessels
arteries, arterioles, capillaries, venules, veins
describe the location of the heart in detail
between lungs, behind sternum, top tilted back, and tilted to the right side
name the heart layers in detail
pericardium (parietal pericardium, pericardial cavity), epicardium (visceral pericardium), myocardium, endocardium
what is the serous membrane around the heart
pericardium
what tissue is not present in the heart
neural
what are the 4 chambers of the heart
RA, RV, LA, LV
what separates the ventricles
septum
what separates the atria
atrial walls
are the ventricles the same size
they were as a newborn, but then the LV gets more muscular from pumping harder and so the RV is bigger
what valve: between RA and RV
right AV valve/tricuspid valve
what valve: between LA and LV
left AV valve/bicuspid/mitral valve
what valve: between RV and pulmonary trunk
pulmonary valve/pulmonic semilunar valve
what valve: between LV and aorta
aortic valve/aortic semilunar valve
what supports the AV valves
chordae tendineae attached to papillary muscles
name the pathway of the blood through the heart and body starting in the left ventricle
left ventricle, aortic valve, aorta, arteries, arterioles, capillaries, venules, veins, superior and inferior vena cava, right atrium, tricuspid valve, right ventricle, pulmonary valve, pulmonary arteries, lungs, pulmonary veins, left atrium, bicuspid valve
1 cycle of contraction and relaxation of heart chambers, heartbeat
cardiac cycle
what are the 3 steps of the cardiac cycle
diastole: heart relaxed, blood filling atria
atrial systole: atria contract, ventricles completely filled with blood
ventricular systole: ventricles contract, blood to body, atria relax
what causes cardiac sounds
blood flow turbulence when a valve closes
what causes the lub sound
turbulence when AV valves close
what causes the dub sound
turbulence when semilunar valves close
what is the equation of cardiac output
HR x SV= CO
does the blood in your body always flow turbulently
no, mostly is laminarly
how much is the CO every minute
5 liters
peak of pressure in aorta when blood flows in
systolic
lowest blood pressure in aorta when blood is flowing out
diastolic
what direction do fluids flow
from high pressure to low pressure
how does blood move through arteries
they stretch when blood is pumped in, then elastic recoil pushes it through
what closes a valve
pressure being greater in front of it
what opens a valve
pressure being greater behind it
what does the heart being autorhythmic mean
it generates its own beat
true/false: the heart has neurons
false
why is the heart autorhythmic
it has specialized myocytes and gap junctions
what do the intrinsic controls of the heart do
establish normal heart beat
pacemaker, upper RA
sinoatrial node
base of RA, causes slight delay
atrioventricular node
where does the electrical signal of the heart go after the AV node
atrioventricular bundle, right and left bundle branches, Purkinje fibers
where does the contraction of the heart
the apex of the heart because it is the shortest distance away from the AV node
why are the contraction origins of the heart beneficial
they start at the apex and move up the heart so it pushes blood up towards the valves and out of the heart
what do the extrinsic controls do
modify heart rate to meet body’s immediate needs, can override intrinsic controls
what 2 cells does the contraction of the heart rely on and what do they do
cardiac myocytes- mechanical pumping, autorhythmic cells- electrical impulses for contractions
in the medulla oblongata, can override intrinsic heart rate, output from autonomic nervous system
cardiomotor center
where do parasympathetic nerves innervate
SA and AV nodes
where do sympathetic nerves innervate
SA node, AV node, and ventricular myocardium
what does the sympathetic nervous system affect
stroke volume, heart rate, cardiac output
what does the parasympathetic nervous system affect
heart rate, cardiac output
what causes contraction of the heart
cell depolarization
what causes relaxation of the heart
cell repolarization
true/false: ECG is a reflection of tissue depolarizing NOT conduction system
true
ECG: what does the P wave show
SA node fires, atria depolarization
ECG: QRS complex show
depolarization of ventricles, atria repolarize but overshadowed
ECG: T wave shows
ventricles repolarize, return to diastole
ECG: P-R interval shows
atrial depolarization to ventricular depolarization
ECG: Q-T interval shows
total time of ventricular depolarization and repolarization
do the mechanical events of the heart exactly match up with the timing of the ECG
no, the mechanical events happen a little after the cell depolarization/repolarization
what is the funny current
calcium, sodium ions into the cells to depolarize them
ECG: P-Q shows
AV node delay, conduction system
can cardiac muscle contract and hold itself there. why or why not
no, the plateau phase of contractile cells involve a refractory period where they can’t contract again for a moment
what does the plateau period of contractile cells ensure
heart diastole and refilling
what is happening in a conduction cell: initial period of depolarization to sub threshold (step 1)
Na+ in, little bit of K+ out
what is happening in a conduction cell: latter period of depolarization to threshold (step 2)
Ca2+ in
what is happening in a conduction cell: rapid depolarization phase (step 3)
Ca2+ in
what is happening in a conduction cell: repolarization phase (step 4)
K+ out
what is happening in a contractile cell: phase 0
rapid depolarization, Na+ in
what is happening in a contractile cell: phase 1
small repolarization, Na+ in decreases
what is happening in a contractile cell: phase 2
plateau, Ca2+ in, K+ out decreases
what is happening in a contractile cell: phase 3
repolarization, K+ out, Ca2+ in decreases
what is happening in a contractile cell: phase 4
resting potential, K+ out, Na+ and Ca2+ impermeable
what structures does the flow of blood naturally go through high to low pressure
artery, arteriole, capillary, venule, vein
where is blood pressure highest
arteries (aorta)
where is blood pressure lowest
veins (inferior vena cava)
where is blood flow fastest
arteries (aorta)
where is blood flow slowest
capillaries, to allow nutrient exchange
what are the 3 layers of an artery from deep to superficial
epithelium, smooth muscle, connective tissue (collagen)
what is the surge of blood flow
pulse
what vessel has the greatest smooth muscle ratio and offers the greatest resistance to flow
arterioles
what are the layers of an arteriole from deep to superficial
epithelium, smooth muscle
how do arterioles regulate blood pressure
constricting or dilating
what are the layers of a capillary
epithelium
what are passages for things that can’t diffuse across capillary lipid bilayer but can dissolve in water
pores
what is it when pressure in capillary is more than outside so water and solutes are forced into extracellular fluid where the lymphatic system picks them up
bulk flow
what are the 3 ways for substances to cross the capillary walls
diffusion, pores, bulk flow
force of fluid on the capillary walls
hydrostatic pressure
describe how fluid ends up in the extracellular space
hydrostatic pressure forces anything small enough through the capillary walls, because of the high concentration of proteins in the capillary, water diffuses back in but a little stays behind, nutrients are left behind for the cells
osmotic pressure because of plasma proteins
oncotic pressure
are there proteins in the interstitial fluid
no
what happens to the little bit of water left behind in the interstitial space
picked up by lymphatic system and returned to bloodstream
what regulates how much blood flows into the capillaries
precapillary sphincter
how does working out affect the precapillary sphincters
working out makes your muscles work harder because your cells are working harder so they/re wasting and releasing more heat, this heat denatures the precapillary sphincters making them relax, so more blood is getting to your working muscles
when there is inflammation where does this happen
venules
what are the 3 layers of venules from superficial to deep
connective tissue, smooth muscle, endothelium
what blood vessels have valves
veins
what are the 3 layers of veins form deep to superficial
endothelium, smooth muscle and elastic fibers, connective tissue
what prevents backflow of blood in veins
valves
how do valves work in veins
skeletal muscles contract which pushes blood through valves
how much of your blood is in your veins
70%
what monitors resting blood pressure
medulla
keeps blood pressure in normal limits in face of sudden changes by sensing when there is less stretch in aorta (low bp) and sends info to medulla to raise heart rate
baroreceptor reflex