AP Bio
Eukaryotic cells
unicellular
with nucleus
mid Proterozoic era
100x larger than bacteria
origin of nucleus and ER
infolding of cell membrane
similar bacteria to psyn membrane
surrounded DNA
formed er
origin of mitochondria and chloroplasts
endosymbiotic theory
Eukaryotic cells take in bacteria as
endosymbionts
Aerobic Bacteria became mitochondria
Cyanobacteria become chloroplasts
endosymbiotic theory evidence 4
1) Two membrane layers of
A) Outer membrane like host cell
B) Inner membrane like a bacteria
2) Mito. & chloro. have their own DNA
Circular Chromosome
Different genes than nucleus
3) Mito. & Chloro have own ribosomes &
Make own proteins
Ribosomes like bacteria
4) Mito & Chloro grow and reproduce on own
Phanerozioc Eon
540 million years ago -present
Phspholipid bilayer
hydrophilic heads phosphate
hydrophobic tails fatty acids
move and held together by hydrophobic interactions
Selective permeability
very small or nonpolar molecules
large polar monomers like glucose slow
ions do not cross
polar macro molecules not cross
cholesterol
found in animal cells
maintains membrane fluidity
high temp restraints phospholipid movement
low temp prevents close packing
membrane proteins
intergral - in the ecm
peripheral- on top of on bottom of ecm
membrane enzymes
often grouped in teams
active in metablism
bind to cytoplasmic structures
attachment proteins
bind to ECM and cytoskeleton
maintain cell shape and location
non-covalent
recognition proteins
. sort cells in embryo
immune system self-recognition
often glycoproteins (glycolipids)
inter cellular joining
a. gap junctions
b. adhering junctions
Receptor Proteins
receptors – bind to chemical messenger
(hormones, cAMP)
b. binding signal molecule changes protein shape
c. signals inside of cell by binding cytoplasmic protein causing transduction
Transport proteins
a. channel proteins (aquaporin)
b. carrier proteins (glucose transporter)
c. protein pump
2 Types of Cellular Transport
Passive Transport = no energy needed
Active Transport = takes energy
diffusion
molecules make it through cell membrane on their own
facilitated diffusion
molecules that have to go through proteins to enter the cell
osmosis
diffusion of water must be through a membrane
tonicity
isotonic, hypertonic, hypotonic
isotonic
no net movement
hypertonic
more solute in solution
hypotonic
less solute in solution
osmoregulation
Control of solute and water concentrations inside a cell
Homeostasis to
remain isotonic
protein pumps
Transport proteins that require energy
Protein pushes molecules into areas where they are in high concentration.
ATP is the energy used
endocytosis
Cell takes in molecules by forming new vesicles at CM
exocytosis
How cells secrete materials like hormones
a. transport vesicle buds from Golgi body
b. vesicle moved to C.M. by motor protein