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A set of 100 flashcards covering the process of meiosis, phases of meiotic division, genetic variation, and types of sexual life cycles as described in the lecture notes.
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How many gametes are required for sexual reproduction according to the lecture?
2 gametes
What is the resulting cell called when two gametes join during fertilization?
A zygote (fertilized egg)
How many sets of chromosomes are contained within a haploid cell?
1 set
How many sets of chromosomes are contained within a diploid cell?
2 sets
What is the specific requirement for sexual reproduction regarding the number of chromosome sets?
It requires nuclear division that splits the number of chromosome sets in half.
What identifies somatic cells in multicellular organisms?
They are all cells that are not gametes or reproductive cells.
What does the abbreviation "HC" stand for in these notes?
Homologous Chromosomes
In somatic cells, what are the matched pairs of chromosomes that have the same genes at the same locations?
Homologous Chromosomes (HC)
Where does a diploid organism receive each copy of its homologous chromosomes?
1 copy from each parent
How is meiosis defined in the context of nuclear division?
The formation of haploid cells from diploid cells.
How do daughter cell nuclei in mitosis compare to their parent nuclei?
They are identical.
What is the ploidy level of the parent nuclei and daughter nuclei in meiosis?
Parent nuclei are diploid and daughter nuclei are haploid.
What are the two main stages of meiotic division?
Meiosis I and Meiosis II
What phase precedes Meiosis I?
Interphase
What occurs during the G1 phase of interphase?
Cell growth
What specific event takes place during the S phase of interphase?
Chromosomal DNA replication
What are the two identical copies of replicated chromosomes called?
Sister chromatids
What proteins hold sister chromatids together at the centromere until anaphase II?
Cohesion proteins
What is the purpose of the G2 phase of interphase?
Final preparations for meiosis
In Prophase I, where are homologous chromosomes attached to the nuclear envelope?
At their tips
What is the synaptonemal complex?
A lattice of proteins that forms between homologous chromosomes.
What process does the synaptonemal complex support?
Crossing over
What is the definition of "crossing over"?
The exchange of chromosomal segments between homologous nonsister chromatids.
What is the first source of genetic variation in nuclei produced via meiosis?
Crossing over
What is the term for the tight pairing of homologous chromosomes during prophase I?
Synapsis
How are genes aligned during synapsis?
Chromatid genes are precisely lined up with one another.
What happens to the synaptonemal complex after synapsis is complete?
It begins breaking down.
What are chiasmata?
X-shaped crossover sections between non-sister chromatids of homologous chromosomes.
Until which phase do chiasmata remain attached?
Anaphase I
What is the minimum number of chiasm per chromosome required for proper separation of HCs in meiosis I?
1 chiasma
What are the pairs of homologous chromosomes called at the end of prophase I when they are held together only by chiasmata?
Tetrads
Between which structures is DNA exchanged during a crossover event?
Between maternal and paternal chromosomes (homologous nonsister chromatids).
What is contained in a recombinant sister chromatid?
DNA from both parents
What is the key event that occurs during Prometaphase I?
Spindle fiber microtubules attach to kinetochore proteins at centromeres.
What are kinetochores?
Multiprotein complexes responsible for the binding of centromeres to microtubules.
How are the members of a homologous pair attached to microtubules during prometaphase I?
Each member is attached to a microtubule from opposite poles of the cell.
At the end of Prometaphase I, each tetrad is attached to microtubules from both poles; how is each HC oriented?
1 homologous chromosome faces each pole.
What structure is completely broken down by the end of Prometaphase I?
The nuclear membrane
Where are homologous chromosomes arranged during Metaphase I?
At the metaphase plate (midline of the cell).
Besides crossing over, what other event in Metaphase I is highly responsible for genetic variation?
The random position of the homologous pairs.
What happens during Anaphase I?
Microtubules pull chromosomes apart.
Do sister chromatids separate during Anaphase I?
No, they remain tightly connected at the centromere.
What specific structures are broken during Anaphase I to allow chromosomes to move apart?
Chiasmata
Where are the separated chromosomes located during Telophase I and Cytokinesis?
At opposite poles
What structure is used in almost all animals and fungi to split the cell during cytokinesis?
A cleavage furrow (constricted actin ring).
How does cytokinesis differ in plants compared to animals?
In plants, a cell plate is formed at the metaphase plate which develops into cell walls.
How many cells are produced from the division of a diploid cell in Meiosis I?
2 haploid cells
Why are the cells after Meiosis I considered haploid even though sister chromatids are still present?
Because there is only one of each pair of the homologous chromosomes at each pole.
How many full sets of chromosomes are present in a cell at the end of Meiosis I?
1 single full set
What is the name of the short interphase that some species enter prior to Meiosis II?
Interkinesis
What phase is specifically lacking in interkinesis?
The S phase (DNA duplication).
What happens to the sister chromatids of the two daughter cells during Meiosis II?
They separate to form 4 new haploid gametes.
What happens to chromosomes in Prophase II if they decondensed in Telophase I?
They condense once more.
What happens to duplicated MTOCs during Prophase II?
They move apart towards opposite poles.
What event characterizes Prometaphase II?
Complete breakdown of nuclear envelopes and full formation of the spindle.
In Prometaphase II, how are sister chromatids attached to microtubules?
To microtubules from opposite poles via individual kinetochores.
Where are sister chromatids aligned during Metaphase II?
At the cellular equator
What is the state of sister chromatids during Metaphase II?
They have reached maximum condensation.
What pulls sister chromatids apart during Anaphase II?
Kinetochore microtubules
What is the role of nonkinetochore microtubules during Anaphase II?
The elongation of the cell
What happens to chromosomes once they arrive at opposite poles in Telophase II?
Decondensation of chromosomes
What forms around the chromosomes during Telophase II?
New nuclear envelopes
What is the final result of cytokinesis after Meiosis II starting from a single diploid parent?
The formation of 4 unique haploid cells.
Are the cells produced at the end of Meiosis II genetically identical?
No, they are genetically unique.
How many nuclear divisions occur in mitosis?
1 single nuclear division
What is the genetic relationship between the two nuclei partitioned in mitosis and the original nucleus?
They are genetically identical.
In mitosis, how many sets of chromosomes are in the daughter cells compared to the parent?
The same number of sets
In mitotic division, where do the single set of duplicated chromosomes align?
On the metaphase plate
What is the only reason the products of meiosis II are not identical like mitosis?
Crossover
Why is mitosis not considered a reduction division?
Because there is still a single set of chromosomes, just as in the start of the division.
How many nuclear divisions occur in meiosis?
2 nuclear divisions
How many nuclei are produced at the end of meiosis?
4 nuclei
How does the chromosome count in meiosis daughter nuclei compare to the original diploid cell?
They contain only half (a single chromosome set).
In which stage of meiosis do the primary differences from mitosis occur?
Meiosis I
Why is Meiosis I referred to as a reductional division?
Because the number of chromosome sets is reduced from 2 to 1.
When is sexual reproduction believed to have appeared in evolutionary history?
Likely as an "evolutionary innovation" after the appearance of eukaryotic cells.
What are two cited advantages of asexual reproduction?
Speed of reproduction and only needing one organism.
Under what condition is it advantageous to produce identical offspring via asexual reproduction?
If the parent is succeeding in a particular habitat.
What is a major explanation for why sexual reproduction is common in multicellular organisms despite the overhead?
Genetic variation and diversity are important for survival and reproduction.
What can happen to mutations during sexual reproduction?
They can be "reshuffled" from generation to generation.
What is defined as the alternating of fertilization and meiosis?
Sexual Life Cycles
How is fertilization defined in the lecture?
The joining of 2 haploid gametes and the restoration of the diploid condition.
What life-cycle type do most animals use?
Diploid-dominant life-cycle
In a diploid-dominant cycle, what are the only haploid cells produced?
Gametes
What are germ cells?
Specialized diploid cells produced in the gonads.
What cell type is capable of both mitosis (for the cell line) and meiosis (for gametes)?
Germ cells
Can haploid gametes in a diploid-dominant life cycle divide again?
No
Which organisms have an obvious multicellular haploid stage?
Fungi and some algae
In the life cycle of fungi, what is the ploidy of the main body?
Haploid
How are haploid cells formed in fungi?
By mitosis
What is formed when special haploid cells from two individuals combine in fungi?
A diploid zygote
What does the diploid zygote in fungi produce through meiosis?
4 haploid cells called spores
What life-cycle pattern is found in plants and some algae?
Alternation of generations
What defines "alternation of generations"?
Having both multicellular diploid and haploid life stages.
What are gametophytes?
Haploid multicellular plants
Is meiosis directly involved in gamete production in gametophytes?
No, gametes are produced from specialized cells.
What results from fertilization between gametes in the plant life cycle?
A diploid zygote
What does the plant zygote become after several rounds of mitosis?
A multicellular diploid plant called a sporophyte.
What is a sporophyte?
A multicellular diploid plant.
What do special cells in the sporophyte produce through meiosis?
Haploid spores