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Ventral
Front
Dorsal
Back
Proximal
Close to
Distal
Away from
Lateral
Side of body
Medial
Middle of body
Superficial
Top level
Deep
Bottom level
Superior
Above
Inferior
Below
Cephalon
Head
Caudal
Tail/feet
Palmar
Palm of hand
Dorsal(dorsum)
Back of hand
Plantar
Bottom of foot
Circumflex
Curved
Afferent
Toward an organ
Efferent
Away from organ
Saggital plane
divides the body into a right and left side
Transverse plane
line that divides the body into upper and lower sections
Coronal plane
divides body into front and back
What are the 5 steps of the scientific method?
Observation, question, hypothesis, prediction, and experiment
Dependent variable
Aspect being measured/tested
Independent variable
Aspect being manipulated
Null hypothesis
opposite of hypothesis
What significance do levels of evidence have?
Less humans involved, less believable. More humans involved, more believable.
What is an example of a less believable evidence level?
Animal/Lab studies, editorials, and expert opinions
What is an example of a more believable evidence level?
Clinical practice guidelines and meta-analysis systematic review
Basic science is
Pure science that may not result in a practical (important) application
Applied science is
Technology science that asks how can we improve?
Properties of life are
Highly organized, sensitive, and can adapt easily
Homeostasis
Regulation to internal and external environment
Set points refer to
When the body resists change, it will work to return to a specific threshold (ex: sweat, shiver)
positive feedback loops
moves away from homeostasis, is short term
what is a good example of a positive feedback loop?
pregancy (release oxytocin, more contractions, eventually back at a homeostasis environment)
negative feedback loops
uses reactions to diminish changes and return back to a set point
what is a good example of a negative feedback loop?
sweating and shivering
as pH decreases, the number of H+ ions ______
increases
does an acid release or accept H+
release (negative OH molecule)
does a base release or accept H+
accept (less are freely loose, accepts more)
what is the pH of blood
7.35-7.45
buffer
pair of substances that minimizes fluctuations in the pH of living organisms
how can the lungs affect the acid base balance?
- exhale CO2, less CO2, less bicarbonate (more acidic)
- inhale CO2, more CO2, more bicarbonate (more basic)
where do most chemical reactions occur?
water
solute and solvent
solution
why do solutes dissolve in water?
polar covalent bonds
what is the relationship of H+ bonds to the states of H20
- solid (many H+ bonds)
- liquid (some H+ bonds)
- gas (no H+ bonds)
changes in state require
energy
cohesion and surface tension create
hydrogen bonds
water is less dense when it is a ________
solid
water has a high specific heat and heat capacity
cohesion
water molecules stick together
water allows for ______ __________
waste elimination
where are protons and neutrons found?
nucleus
covalent bonds
share electrons, they are strong, could form partial charges
nonpolar covalent
equal sharing, no partial charges
polar covalent
unequal sharing, partial charges possible
hydrogen bond
weak bonds, form because H+ is more positive, and attracted to negative charges
what is an example of hydrogen bonds within a molecule?
DNA (H bonds form between the nucleotides on either side of the double helix)
van de Waals
very weak bonds, similar to magnets
ionic bonds
forms when a cation (+) binds to an anion (-), powerful bonds
biological membranes
contains phospholipids, proteins, and carbohydrates
plasma membranes
thin, somewhat "fluid", separates inside and outside
Internal membranes
form organelles
selective permeability
selective uptake and export of ions and molecules
what do proteins do within the phospholipid bilayer?
ion, molecule, and polar molecules get transported
integral membrane proteins
embedded in membrane where portion is integrated into the hydrophobic region (to allow things that are charged or too large to pass through)
peripheral membrane proteins
sit on the membrane, not in.
- anchor the cytoskeleton
- anchor cells together
- send signals to other cells, can identify other cells
what does more bonds do to the fluidity of the membrane?
more bonds, less fluid (membranes should be structurally sound but flexible)
if nonpolar tails are short, that means
the membrane is more fluid
if there are double bonds in the membrane, that means
more fluid
kink
less able to interact
what does the presence of cholesterol do?
stabilize membranes
- higher temp means less fluid
- lower temp means more fluid
what does collagen create?
the basement membrane
passive transport includes
simple diffusion and facilitated diffusion
simple diffusion
is a kind of passive transport that does not involve proteins. can transport small non-polar items, such as O2 and CO2. moves down the gradient
facilitated diffusion
is a kind of passive transport that involves transmembrane proteins. transports slightly larger, more charged or polar items. moves down the gradient
active transport
is a kinds of transport that requires energy (ATP) and moves ions against the gradient. confirmation changes happen and Na/K+ pump is an example
can ions and hydrophilic molecules diffuse through the membrane?
NO
what are the 4 factors that affect the diffusion across the bilayer?
size, polarity, charge, and concentration
electrochemical gradient
- inside is more negative
- outside is more positive
osmosis
the movement of water across membranes to balance solute concentrations
tonicity
the ability to dilute
osmosis and tonicity are affected by
solute concentration
what happens when cells are placed in a hypertonic solution
cells undergo shrinkage, loss of H20
what happens when cells are placed in a hypotonic solution
cells swell and may rupture, add of H20
secondary active transport
involves the use of a pre-existing gradient to drive the active transport of another solute
what is the Na+/K+ pump an example of
an antiporter using primary active transport
Na + is ___ inside the cell and ___ outside the cell
negative, positive
K+ is ___ inside the cell and ___ outside the cell
positive, negative
blood is what kind of tissue
a liquid connective tissue
cytosol
where most reactions happen, the fluid!
rough ER
contains ribosomes that create AAs
metabolism
sum of chemical reactions by which cells produce the materials and utilize the energy necessary to sustain life
what is a good example of metabolism
glycolysis
intracellular communication
between cells
intercellular communication
within cells
catabolism
breaks down molecules, releases energy (hydrolyze ATP)
anabolism
synthesis of molecules, requires energy (ADP + P group = ATP)
cytoskeleton
gives us shape, not rigid