WGU - D313 - Anatomy and Physiology 2 Lymphatic System Test Questions with 100% accurate solutions 2026-2027

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Last updated 7:30 AM on 7/5/26
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121 Terms

1
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What does the red pulp of the splenic nodule consist of?

reticular fibers

3 multiple choice options

2
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What is a primary function of a lymph node?

filter bacteria out of the blood

3 multiple choice options

3
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What is an example of a primary lymphoid organ?

thymus

3 multiple choice options

4
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Which vessel do the right side of the face, neck, right upper extremity, and right thorax drain into?

right subclavian vein

3 multiple choice options

5
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Through which structure does lymphatic fluid enter the lymph node?

through the afferent lymphatic vessel

3 multiple choice options

6
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Which circulatory pathway leads to bacteria being removed from the body?

lymphatic

3 multiple choice options

7
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What is the first line of defense when pathogens breach the defense barriers of the body?

phagocyte cells

3 multiple choice options

8
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Which cell performs the major function of bringing antigens to regional draining lymph nodes during antigen presentation?

dendritic cells

3 multiple choice options

9
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Which cells are involved in the second stage of inflammation?

macrophages

3 multiple choice options

10
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What is another term for epitope?

antigenic determinant

3 multiple choice options

11
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Which type of adaptive immune cell regulates other types of immune cells?

helper T cells

3 multiple choice options

12
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Which immune system component is found in breast milk?

antibodies

3 multiple choice options

13
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Where do T cells mature?

thymus

3 multiple choice options

14
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At which phase of human development is the thymus gland at its largest?

young child

3 multiple choice options

15
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Which statement is correct about the lymph node?

lymph nodes contains macrophages and lymphocytes

3 multiple choice options

16
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What are 2 functions of the red pulp of the spleen?

acts as an important reserve for platelets and red blood cells

removes worn-out red and white blood cells and platelets

3 multiple choice options

17
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Which lymphatic tissue is found in the small intestine?

GALT

2 multiple choice options

18
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Where is the most active marrow found?

heads of the femur and humerus

3 multiple choice options

19
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Which structure is a secondary lymphatic organ?

lymph nodes

2 multiple choice options

20
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In which part of the human body are lymph nodes commonly found?

groin

3 multiple choice options

21
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What is the function of the tonsils?

protection from inhaled and ingested pathogens

3 multiple choice options

22
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Which structure holds the capillaries in place?

anchor filaments

2 multiple choice options

23
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Which structure receives from the left side of the body and lower right side?

thoracic duct

3 multiple choice options

24
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How does respiratory muscle help with lymphatic circulation?

it maintains low thoracic pressure

2 multiple choice options

25
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Which structure is about 38-45 cm long and forms the largest confluence of lymphatic vessels in the body?

thoracic duct

2 multiple choice options

26
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Which statements are true regarding the lymphatic system?

it drains the excess fluid via a series of ducts, vessels, and trunks

lymph is the term used to describe interstitial fluid once it has entered the lymphatic system

3 multiple choice options

27
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In humans, ______ liters of plasma are released into the interstitial space of the tissues each day due to capillary filtration

30

3 multiple choice options

28
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Which cells quickly arrive at the site of inflammation to engulf microbes and differentiate into macrophages and dendritic cells?

monocytes

3 multiple choice options

29
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What are monocytes that quickly arrive at the site of inflammation to engulf microbes and differentiate into macrophages and dendritic cells?

phagocytic cells

3 multiple choice options

30
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Which element chemically protect the body?

sebum

2 multiple choice options

31
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During which stage of phagocytosis do receptors on the surface of the phagocyte bind to microbes?

adherence

3 multiple choice options

32
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In which stage is the DNA of uninfected cells transcribed?

translation of antiviral protein

3 multiple choice options

33
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Which phagocyte is the first to migrate to the site of tissue damage?

neutrophils

2 multiple choice options

34
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Through which actions does the thermoregulatory center in the hypothalamus adjust body temperature from hypothermia levels to regular body temperature?

vasoconstriction

3 multiple choice options

35
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Which cells are fixed macrophages that are present in the liver?

kupffer

3 multiple choice options

36
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Which statement is true regarding the natural killer cells?

they originate in the red bone marrow and are concentrated in the spleen and lymph nodes

3 multiple choice options

37
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What is considered the first line of defense against foreign substances?

urine

tears

3 multiple choice options

38
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What is true regarding the first stage of inflammation?

permeability of blood vessels increases at the site of damage

3 multiple choice options

39
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Which lymphocyte is the first to react to infection?

natural killer cells

2 multiple choice options

40
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Which cells can recognize foreign particles previously encountered?

memory cells

3 multiple choice options

41
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Which characteristic applies to the MHC class I molecule?

found on every cell in the human body except red blood cells

3 multiple choice options

42
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Why has the development of an HIV vaccine been a challenge?

the virus mutates rapidly

2 multiple choice options

43
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Which statement is correct regarding B cells?

an activated B cell produces and secretes antibodies

3 multiple choice options

44
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Antigens are referred to as being immunogenic. Under which condition is a substance less likely to be immunogenic?

under none of these conditions

3 multiple choice options

45
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Which one of of these is not a type or version of the T cells?

plasma cells

3 multiple choice options

46
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Which statement is correct regarding HIV/AIDS?

the first signs of infection are generally flu-like symptoms 1-2 weeks after infection

3 multiple choice options

47
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What is the name of the organ that fights invading germs in the blood?

spleen

3 multiple choice options

48
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What are the primary lymphoid organs in the human body?

bone marrow and thymus gland

3 multiple choice options

49
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Which cell is phagocytic?

neutrophils

3 multiple choice options

50
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Which structure allows lymph from the lower right limb to enter the bloodstream?

thoracic duct

3 multiple choice options

51
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Which cell would react quickly the first time one is exposed to a pathogen?

natural killer cell

3 multiple choice options

52
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Which lymphoid structure is most likely to encounter food antigens first?

tonsils

3 multiple choice options

53
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Where does the T cell develop and multiply?

thymus

3 multiple choice options

54
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Which part of the body is drained with the right lymphatic duct?

right side of head, thorax, and right arm

3 multiple choice options

55
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As the first phagocytes to arrive at the site of inflammation, ______ secrete cytokines to attract other immune cells to the site of infection

neutrophils

3 multiple choice options

56
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Which structure of the lymphatic system removes dead red blood cells from the blood?

spleen

3 multiple choice options

57
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Which cells are activated by interferons and cytokines and destroy cells infected with a wide range of viruses and cancers?

natural killer cells

3 multiple choice options

58
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What are the primary cells of the adaptive immune response?

lymphocytes cells

3 multiple choice options

59
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Why does the human body have natural antibodies?

to provide immunity to environmental bacteria

2 multiple choice options

60
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Which type of immune cell is most directly effective against bacteria?

complement cell

3 multiple choice options

61
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Which type of immune cell works in concert with cytotoxic T cells against virally infected cells?

natural killer cells

2 multiple choice options

62
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Which situation leads to the redness of inflammation?

increased blood flow

3 multiple choice options

63
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The process that signals to phagocytes that the pathogen needs to be ingested is called _______

opsonization

3 multiple choice options

64
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Which type of immune cell secretes chemical messengers?

T lymphocyte cell

3 multiple choice options

65
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Which cells are important in the innate immune response?

macrophages

3 multiple choice options

66
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Where do multipotent stem cells mature into immunocompetent B cells and pre-T cells?

red marrow

3 multiple choice options

67
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Which two body systems pumps the lymph fluid to the blood system?

skeletal and respiratory muscle pumps

3 multiple choice options

68
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What is considered the second line of immune defense?

fever

2 multiple choice options

69
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Which natural killer cell granule creates holes in the plasma membrane?

perforin

3 multiple choice options

70
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How does interferon function?

it prevents the replication of viruses

2 multiple choice options

71
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Damage occurs if a fever temperature rises too high. Death results if fever reaches _____

112 f

3 multiple choice options

72
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A nurse is poked accidentally by a needle through gloved after injecting the patient.

Has the infection passed the first line of immune defense? If yes, which first line of defense is breached?

yes, skin

3 multiple choice options

73
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How will the nurse's immune system respond to this event?

vasodilation, chemotaxis, and diapedesis of neutrophils and natural killer cells will occur

3 multiple choice options

74
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A nurse is poked accidentally by a needle through gloved after injecting the patient.

How does the body recognize the entry of hepatitis B virus?

with help of MHC, the infected cell is introduced to T cells

2 multiple choice options

75
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A nurse is poked accidentally by a needle through gloved after injecting the patient.

How would the body initially respond if the nurse was not vaccinated?

the body would produce a fever and increase adaptive immune response by activating helper and cytotoxic T cell

3 multiple choice options

76
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Adaptive immunity can be divided into which two main processes?

antibody-mediated immunity

cell-mediated immunity

3 multiple choice options

77
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Where do B and T cells generate from?

bone marrow for both

2 multiple choice options

78
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What is the role of the B cell?

to make plasma cells and ultimately antibodies

3 multiple choice options

79
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How do macrophages help to counter infection?

by engulfing the pathogen and lysis with lysosomes

3 multiple choice options

80
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______ immunity attacks pathogens that have invaded the cells of the body. It is controlled by _______, which react to antigens present on the surface of the infected cells, triggering their destruction

cell-mediated, T cells

3 multiple choice options

81
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Some daughter cells of an activated T lymphocyte will become these cells which use cytokines to activate other immune cells

helper T cell

2 multiple choice options

82
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The cell signaling molecule that causes vasodilation and increased capillary permeability to bring nutrients and leukocytes to an injury as part of the inflammatory response

histamine

2 multiple choice options

83
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This programmed cell death can be triggered by, for example, cytotoxic T cells when they find a cancerous body cell, or one infected by a virsu

apoptosis

2 multiple choice options

84
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Chemical signals, released at the site of an injury or infection, that travel to the hypothalamus and trigger an increase in body temperature, or fever

pyrogens

2 multiple choice options

85
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Collections of lymphoid tissue embedding in the tissues lining the respiratory and digestive tracts

mucosa-associated lymphoid tissue

2 multiple choice options

86
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Collections of lymphoid tissue that form a ring around the pharynx

tonsils

2 multiple choice options

87
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The specific and versatile collection of cellular-based and antibody-based components of the immune system, including T lymphocytes and B lymphocytes

adaptive defenses

2 multiple choice options

88
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Cells like macrophages and neutrophils that indiscriminately ingest pathogens as part of the innate defenses

phagocytes

2 multiple choice options

89
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The watery fluid, electrolytes, proteins and other materials, and white blood cells that flow through the lymphatic system

lymph

2 multiple choice options

90
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Derived from monocytes, these "big eaters" crawl around tissues looking to envelop and digest pathogens

macrophages

2 multiple choice options

91
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The type of lymphocyte responsible for cellular immunity, these mature in the thymus, read presented antigens, and regulate much of the adaptive immune response

T lymphocytes

2 multiple choice options

92
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The vessel drains lymph from the legs, abdomen, left thorax and head, and dumps it into the left subclavian vein

thoracic duct

2 multiple choice options

93
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The collection of cells and structures - like skin, mucous membranes, phagocytes, and antimicrobial proteins - that provide general immunity and defenses from infection from birth

innate defenses

2 multiple choice options

94
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Antimicrobial peptides found on the skin and mucous membranes

defensins

2 multiple choice options

95
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The small vessels that pick up excess interstitial fluid and transport it to be checked for signs of infection and returned to the bloodstream

lymphatic capillaries

2 multiple choice options

96
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The triggering of a primary adaptive immune response by injecting an inactivated or extremely weakened pathogen

vaccination

2 multiple choice options

97
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The type of immunity gained when exposure to a pathogen triggers the adaptive defenses to make antibodies and memory B cells, so that a future secondary response is possible

active immunity

2 multiple choice options

98
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The protein on which cells can present whole or partial antigens they have engulfed, or are infected by

major histocompatibility complex

2 multiple choice options

99
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The type of immunity gained by transferring just antibodies, as with breast milk, so that immunity is temporary and no memory B cells are formed

passive immunity

2 multiple choice options

100
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The part of the adaptive immune system that involves activated T cells directly destroying virus-infected or cancerous cells

cellular immunity

2 multiple choice options