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major killers of americans @ turn of 20th cent
tuberculosis and pneumonia
By 1925, diseases of the _____ had become the number one cause of death in the United States, followed by __________
heart; pneumonia and influenza
By the 1940s, ______ had edged out ________ for the dubious distinction of being the nation’s second most lethal disease
cancer; pneumonia
Today, ___________ account for nearly half of all deaths in the United States
heart disease and cancer
Approximately ______ of all adults in the United States have at least one chronic health condition
half
Approximately ______ of all adults in the United States have at two or more chronic health conditions
one quarter
refers to the biochemical processes involved in the body’s functioning
metabolic
Every day more than ______ Americans die of cardiovascular diseases—an average of one death every ___ seconds
2,200; 39
Cardiovascular diseases (all diseases of the heart and blood vessels) account for ______ deaths, including an increasing number among younger adults age 35 to 54
1 in every 3
Only about ______ of young Americans get passing grades for heart-healthy behaviors
half
Only about ______ of young Americans get passing grades for heart-healthy behaviors
half
Fewer than ___ percent of young Americans eat “ideal” diets
1
What amount of young Americans have unfavorable BMIs
one-third
Sleep study of young adults age 21 to 35
sleep disturbances (< 6 hours of sleep and > 60 minutes wake time after sleep onset) increased risk for metabolic syndrome due to higher waist circumference and an increase in the hormones related to hunger and satiety
recommended excerise amount / week
150 minutes of moderate intensity or 75 minutes high intensity
fat located under the skin
subcutaneous fat
visceral (abdominal)
The more ________ fat that you have, the more resistant your body’s cells become to the effects of your own insulin
risk waist measurements for men and women
40 in men, 35 in women
Among college students, the ratio of __________ can be a significant predictor of metabolic syndrome.
muscle mass to visceral fat
avg screen usage of 18 to 39 year olds
239 minutes a day
break from sitting reccomendation
5 minutes every 30 minutes
_____________________ can be signs of high blood glucose.
Frequent thirst, blurry vision, weakness, unexplained weight loss, and unusual hunger
heart contraction BP
systolic
between contraction BP
diastolic
how to read BP
systolic over diastolic
measurement of BP
mmHg
hypertension can cause
Shortness of breath with exertion
Damage to the arteries in the kidneys, which can lead to kidney failure
Accelerated development of plaque buildup in the arteries.
at risk HDL level
40 mg/dL or lover
avg HDL 4 men
45mg/dL
avg HDL 4 women
55mg/dL
at risk LDL level
100mg/dL or higher
these fats flow through the blood specifically after meals
triglycerides
Blacks and Hispanics have _____ the rates of diabetes as Whites.
double
Nearly __________ Black adults have cardiovascular disease.
4 in every 10
3 in 10
Among Hispanic Americans, nearly ________ have cardiovascular disease.
describe metabolic syndrome trends among teens
lower levels of triglycerides, higher levels of HDL, but also higher obesity
metabolic syndrome indicators
waist measure, triglyceride, HDL, BP, fasting Blood Sugar
how many risk factors do you need to have to be considered to have metabolic syndrome
3 or more
waist for diabetic predispo metabolic syndrome
37-39 inches in men, 31-35 inches in women
metabolic syndrome triglyceride
> 150mg/dL
HDL metabolic syndrome
< 40 mg/dL 4 men, < 50 mg/dL 4 women
BP for meta syndr
> 130 mmHg systole over 85 mmHg diastole (130/85)
blood sugar for metab synd
> 110 mg/dL
metab syndrome to heart attack / stroke risk
2x likely
metab syndrome to heart disease
3x
men w 4 or 5 characteristics of metab synd heart attack / stroke risk
4x
men w 4 or 5 characteristics of metab synd diabetes risk
24x
Young adults with metabolic syndrome are more likely than others their age to have __________, an indicator of atherosclerosis, the buildup of fatty plaques in arteries
thicker neck arteries
Young adults with metabolic syndrome are more likely than others their age to have thicker neck arteries, an indicator of __________, the buildup of fatty plaques in arteries
atherosclerosis
the buildup of fatty plaques in arteries
atherosclerosis
Among those who are obese, losing ______ percent of their body weight may reverse the symptoms of metabolic syndrome.
7 to 10
what are the weak acids produced by the body when breaking down fats for energy
ketones
what is ketoacidosis
an upheaval in the body’s chemical balance that brings on nausea, vomiting, abdominal pain, lethargy, and drowsiness
how many americans have diabetes
29 million, almost 1 in 10
The Centers for Disease Control and Prevention (CDC) projects that up to _____ of Americans could have diabetes by 2050 if they continue to gain weight and avoid exercise.
one-third
what amount of adults in the US can be assessed as prediabeteic?
one-third or 79 million adults
what percent of prediabetics are aware of the risk
less than 10 percent
blood glucose for normal, to prediabetic, to diabetic
70-100, 101-125, > 126 mg/dL
avg loss of life for type 1 diabetes
11 years for men and 13 years for women
causes of death from type 1 dia ranked
heart conditions, diabetic coma, other causes
men vs women in type 1 dia
women 40% greater risk from any cause double of heart disease than men
why are women more in danger due to typew 1 dia
high levels of BSug cause more damage to womens blood vessels
what percent of diabetics are type 2
90-95%
functional diff between type 1 and type 2 dia
type 1 is autoimmune, type 2 is not enough insulin or unable to use insulin
genetic risk factor diffs in type 1 and 2 dia
type 1 needs both parents, type 2 is only a family hist risk in westernized countries
Children of mothers who develop gestational diabetes early in pregnancy may be at increased risk for ________
autism spectrum disorders
What race develops diabetes at lower weights
asians
why do asians develop dia at lower weights
bisceral fat around internal organs
tests to detect dia
random BSug, fasting BSug, Glucose challenge
diabetes symptoms
Increased thirst and frequent urination.
Flulike symptoms.
Weight loss or weight gain.
Blurred vision.
Slow-healing sores or frequent infections.
Nerve damage (neuropathy)
Red, swollen, tender gums.
diabetes ABCs
A1c test, BP, Cholest
A1c blood glucose ADiaA recc, ACEndocrin recc
< 7%, < 6.5%
A1c methodol
measures hemoglobin (iron rich molec) attached to red blood cells to indicate blood glucoseA1c blood glucose ADiaA recc
LDL goal for more people NOT RISK FACTOR
< 160 mg/dL
ADiaA advise for mild to mod physical act for diabetics
mild to mod physic acti for 3 min @ 30 min interval
treatment diffs for type 1 or type 2 dia
type 1 needs insul, type 2 can manage through diet, exercise, and weight, but also may need insulin
how many pancreas transplants/year
400 to 500
how many pancre transpl func after a decade
only abt half
surgery that “cures” diab
gastric bypass
how does gastric bypass cure dia
changing the hormones and ammino acids produced during digestion
how many US adults over 20 have hypertension
one third, some 80 million
“silent killer”
hypertension
Since 2000, the overall death rate from hypertension has increased ___ percent for both men and women, with the greatest spike in those age ______
23; 45 to 64
Regulating blood pressure for all Americans could prevent ______ heart attacks and strokes and 13,000 deaths each year.
56,000
However, ___ percent of adults with elevated blood pressure do not have it under control
44
Globally, treating half of people with uncontrolled high blood pressure could prevent ______ heart attacks and strokes over 10 years
10 million
In individuals with a genetic risk, high blood pressure may spur
development of the brain plaques characteristic of Alzheimer disease
High blood pressure can damage the structure of the brain in people as ______.
young as age 40
Among college students, ______ has been linked with an increased short- and long-term risk of hypertension
binge drinking
According to the CDC, about _____ adults age 18 and older in the United States—some _____ men and women—have high blood pressure.
3 in 10; 65 million
A rise of as little as _______ in systolic blood pressure in Blacks raises the risk of dying
10 mmHg
People with chronic insomnia who take longer than _____ to fall asleep may have a ________ higher risk of high blood pressure. The longer before sleep onset, the greater their risk
14 minutes; 300 percent
BP categories
normal, elevated, stage 1, stage 2, hypertensive crisis
normal, elevated, stage 1, stage 2, hypertensive crisis levels
< 128/80, 120-129 / < 80, 130-139/80-89, > 140 / > 90, > 180 systolic and/or > 120 diastolic
In healthy adults, blood pressure screening should begin at age ___
51
According to the National College Health Assessment survey, ______ of undergraduates have been diagnosed or treated for high blood pressure
3.2 percent
low sodium intake risk factor
< 3g / day
high sodium intake for ppl with hypertension
> 7 g day
one of the new suspects in heart disease risk that is lowered by DASH
homocysteine
lipoprotien profile
tests after 9-12 hour fast, total cholest, LDL, HDL, triglycerides