1/84
I might kms
Name | Mastery | Learn | Test | Matching | Spaced | Call with Kai | Chat |
|---|
No analytics yet
Send a link to your students to track their progress
what does the urinary system filter
blood
what does the urinary system regulate
water
blood volume
blood ionic composition
bloods pH
what does the urinary system produce (hormones)
erythropoietin and renin
Which vitamin is active by the urinary system
Vitamin D (calcium absorption)
What process is started by the urinary system
Gluconeogenesis
Urine formation and blood composition adjustment involves which processes?
glomerular filtration
tubular resorption
tubular secretion
Kidney location
retroperitoneal in the superior lumbar region
how big are the kidneys
12 cm long and weigh 150g
external kidney anatomy consists of…
renal fascia
perirenal fat capsule
fibrous capsule
renal hilus
what does the Renal Fascia do
Anchors kidney to surrounding structures
what does the perirenal fat capsule do
cushions kidneys
what does the fibrous capsule do
Protects kidneys from surrounding tissue and adrenal glands
what is renal ptosis/nephroptosis
loss of the adipose capsule due to weight loss or damage
what happens to the kidneys with ptosis
they drop to a lower position
what happens to the ureters with ptosis
they can become kinked and urine backs up
what is hydronephrosis
pressure builds up in the kidneys and they fail
what is the internal anatomy of the kidneys
cortex
medulla
renal pelvis
what does the cortex look like
grey and granular
what does the cortex contain
nephrons and renal columns
what are nephrons
filtering units
what do the renal columns do
separate medullary pyramids
what does the medulla contain
renal pyramids
papillae
minor calyx
major calyx
what do renal pyramids contain
urine collecting tubules
what is the papillae
pointed area where the pyramids end
what does the minor calyx do
collects urine
what does the major calyx do
combines the minor calyxes
what does the renal pelvis do
collects urine and is continuous to the ureter and eventually bladder
what are the two nephrons
cortical
juxtamedullary
cortical
barely loops into medulla
juxtamedullary
loops deeply into the medulla and is responsible for water conservation
2 parts of the nephrons
renal corpuscle
renal tubule
2 parts of renal corpuscle
glomerulus/glomerular
glomerular capsule
glomerulus/glomerular
fenestrated capillary
glomerulus capsule (Bowmans)
delivered filtrate to renal tubule
renal tubules
basement membrane with simple layer of epithelial cells
proximal convoluted tubule
most absorption occurs here
nephron loop
descending loop
ascending loop
descending limp
water only
ascending loop
solutes only
distal convoluted tubule
fine tunes solute
collecting duct
concentrates or dilutes the urine according to the body’s needs
capillary beds
glomerulus
peritubular capillaries
glomerulus
specialized for filtration, high pressure in afferent arteriole
peritubular capillaries
extension of the efferent
vasa recta
straight capillaries important in concentrating urine
renal arteries
supply blood either to the left or right
interloper arteries
brings blood through the renal columns and between renal pyramids
arcuate arteriole
an arch between the medulla and cortex
afferent arteriole
carries blood into each nephron
glomerular capillary
where exchange takes place
efferent arteriole
carries blood out of glomerular capillaries
peritubular arteriole
carries blood out of glomerular capillaries
peritubular capillaries
surronds tubular parts of nephron
peritubular venues
go from arcuate vein to interloper veins
3 layers of the filtration membrane
fenestrated endothelium
basement membrane
visceral membrane
fenestrated endothelium (filtration membrane)
in glomerular capillary, allows all plasma components besides blood cells to pass
basement membrane
between the fenestrated endothelium and visceral membrane
visceral membrane
this and the podocytes stop most proteins from entering
mesengial cells
can contract and change the surface area for exchange in the capillary
usable solutes must be absorbed in
the tubules
filtrate
blood plasma without the proteins
urine
mostly metabolic wastes and unneeded solutes
how much of 180L blood derived fluid processed by kidney leaves as urine
1.5L
the 2 pressures of glomerular filtration
HPg
passive, nonselective process forcing fluids and solutes into the filtration membrane
Blood colloid osmotic pressure (OPg) and Capsular pressure (HPc) function
opposes hydrostatic pressure
net filtration pressure equation
HPg – (OPg + HPc)
glomerular filtration rate
total Amt of filtrate formed per min by the entire kidney
Avg glomerular filtration rate
125 mL/min
Glomerular filtration rate is based on…
the surface area of the filtration membrane
membrane permeability
net filtration pressure
what regulates the glomerular filtration rate
renal autoregulation
sympathetic control
hormonal control
types of renal auto regulation
myogenic
juxtaglomerular apparatus
myogenic auto regulation
when elevated blood pressure stretches to arterioles
what does myogenic auto regulation do
constricts arterioles
decreases glomerular filtration rate
takes seconds
what does myogenic autoregulstion does with low blood pressure
dilation of arterioles
increased glomerular filtration rate
juxtaglomerular apparatus
tubuloglomerular feedback
consists of juxtaglomerular cells and macula dense
juxtaglomerular cells
mechanoreceptors, sense blood pressure, secretes renin
macula densa
chemoreceptors that sense solute content
will cause dilation or constriction in afferent arteriole
stimulation of extrinsic control or sympathetic nervous system causes was
NE release which causes vasocontriction
when is the extrinsic control/ sympathetic nervous system most effective
excersizing or when hemorrhaging occurs
renin angiotensin system
renin released by juxtaglomerulus cells because of low BP
what does renin produce
angiotensin ii
what is angiotensin ii
potent vasoconstrictor or afferent and efferent arteriole
the renin angiotensin system triggers the release if which hormone
aldosterone and ADH
the renin angiosterone system decreases what
peritubular capillary hydrostatic pressure allowing fluid back into peritubular capillary
the surface area of glomerular ca