Amniocentesis, CVS, Cell-free Fetal DNA Testing

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15 Terms

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Amniocentesis

diagnostic test following an abnormal triple test

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what is an example of an an abnormal triple chromosome

trisomy 21-down syndrome

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which happens first CVS or Amniocentesis

CVS

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Which weeks does CVS occur?

What about amniocentesis?

10-12 weeks of pregnancy

14-20 weeks

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cell culture

biochem studies of chromosomyl analysis-using recombinant DNA methods

cells are grown in a lab setting

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What does amniocentesis and CVS obtain and for what?

Cells(amniotic fluid)(chorionic villus) for karyotyping

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How do you know where the safe location is for the needles to enter the amniotic sac?

an ultrasound

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What is removed in amniocentesis?

Amniotic fluid

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What does amniotic fluid contain?

Cells shed by the fetus

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What makes up the placenta?

Chorion(wispy projections)

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In CVS what is the ultra sound used to do?

In Amniocentesis what does the ultrasound used for?

  1. determine the position of the fetus and placenta

  2. determine a safe location for the needle to enter the amniotic sac

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What is the benefit of cell-free fetal DNA testing?

Non-invasive and done with a finger prick

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What does the accuracy of cell-free fetal DNA testing depend on?

The concentration of fetal DNA circulating in the maternal blood

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Is Cell-free DNA testing done around the time of CVS or amniocentesis?

CVS-week 10

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what are the levels of accuracy for amnicentesis and CVS?

98-99%