Amniocentesis, CVS, Cell-free Fetal DNA Testing
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15 Terms
Amniocentesis
diagnostic test following an abnormal triple test
what is an example of an an abnormal triple chromosome
trisomy 21-down syndrome
which happens first CVS or Amniocentesis
CVS
Which weeks does CVS occur?
What about amniocentesis?
10-12 weeks of pregnancy
14-20 weeks
cell culture
biochem studies of chromosomyl analysis-using recombinant DNA methods
cells are grown in a lab setting
What does amniocentesis and CVS obtain and for what?
Cells(amniotic fluid)(chorionic villus) for karyotyping
How do you know where the safe location is for the needles to enter the amniotic sac?
an ultrasound
What is removed in amniocentesis?
Amniotic fluid
What does amniotic fluid contain?
Cells shed by the fetus
What makes up the placenta?
Chorion(wispy projections)
In CVS what is the ultra sound used to do?
In Amniocentesis what does the ultrasound used for?
determine the position of the fetus and placenta
determine a safe location for the needle to enter the amniotic sac
What is the benefit of cell-free fetal DNA testing?
Non-invasive and done with a finger prick
What does the accuracy of cell-free fetal DNA testing depend on?
The concentration of fetal DNA circulating in the maternal blood
Is Cell-free DNA testing done around the time of CVS or amniocentesis?
CVS-week 10
what are the levels of accuracy for amnicentesis and CVS?
98-99%
