Metabolism 1: PCr and Glycolysis

Adenosine Triphosphate (ATP)

Cellular energy currency

What releases the energy in ATP that the cell can use?

ATP Hydrolysis

Every day you turn-over (breakdown and resynthesize) an amount of ATP roughly equivalent to ________

your body weight

Creatine Phosphate ________

Replenishes ATP

Creatine phosphate + ADP →← ______

Creatine + ATP (catalyst is Creatine Kinase)

Creatine kinase takes a phosphate from the creatine and attaches it to the ADP to form ATP

The reverse can happen depending on the concentration of reactants

Creatine supplementation Key Physiological effects:

1. Increases phospho-creatine pool in the cell

2. Increases ATP buffering

3. Increases muscle mass and strength with resistance exercise

4. Improves muscle recovery and repair after damage

Emerging research: may prevent neurodegeneration

Energy from food → ____ → _______

ATP, Energy for cell work

ATP Production from Glucose