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75 bpm
average contraction rate
70 mL per contraction at rest
cardiac output averages
location of heart
SPECIFIC: Pericardial cavity
Thoracic Cavity
BROAD: Ventral Cavity
apex
points left & sits in left lung’s cardiac notch
size
fist
9-12 ounces b/t male & female
looped, closed system
pumps in a system not open to outside
2 lobes
left lung
capillaries
where nutrients & O2 reach in tissues to deliver to cells
site of exchange
1 cell thick = efficient
systemic circuits
left side
endocardium
simple squamous endothelium cells (1 flat layer) lines chambers & valves
inner
bright blue layer

mesothelium
simple squamous layer
1 cell thick, flat layer
myocardium
striated = protein lines
branched cells
thicker left side > overcome resistance
dark pink layer

epicardium
lays over heart, made of simple squamous cells
aka visceral layer
epi = on top of
light pink layer

visceral layer
touches heart
part of serous pericardium
aka epicardium
light pink layer

serous pericardium
2 layers
double fold membrane that secretes serous fluid (lubricant) b/t layers
visceral, parietal
light pink and light blue layer

parietal layer
outer serous pericardium
touches thoracic wall
light blue layer

fibrous pericardium
sac enclosing heart
tough
serous fluid
secreted by serous pericardium
lubricant
dark blue layer

coronaries
arise off aorta > left coronary super imporrtant + branches
right coronary artery
supplies right atrium & right ventricle
connected to aorta, to heart
coronary sinus & veins
drain heart to right atrium = O2 poor
atherosclerosis
fat plaque build up = narrow & harden arteries > lead to myocardial infarction (heart attack)
veins have valves that…
… keep blood moving 1 way
heart
muscle that needs O2 blood
sinus
cavity that connects to vein in this context
left coronary artery
divides into two branches
goes to left atrium and left ventricle
sends to circumflex artery
circumflex artery
supplies blood to elft atrium and back of left ventricle
arrow to LAD
left anterior descending artery (LAD)
supplies blood to front and bottom of left ventricle and septum
coronary veins
take oxygen-poor blood that has been used already by muscles of the heart and return it to right atrium
pulmonary arteries
fetal umbilical arteries (2)
only time when we have O2 poor blood in an artery
pulmonary veins
umbilical vein (1)
only time we have O2 rich blood in veins
3 adaptations: DV, OF, DA
bypass lungs bc they have fluid in them
fetal circulation adaptations
supposed to close up once born
1 umbilical vein
off placenta, sends rich O2 to fetal heart
2 umbilical arteries
branch off iliac arteries of fetus
return O2 poor/CO2 to placenta
placenta
exchanged piece, (membrane)
O2 and nutrients exchanged here
iliac
legs region
congenital defects
coarctated (narrow) aorta
patent foramen ovale & patent ductus arteriosus: does not close > flow issues
tetralogy of fallout
4 congenital defects
1) pulmonary stenosis
2) right ventricular hypertrophy
3) overriding aorta
4) ventricular septal defect
pulmonary stenosis
narrowing > flow issues
Ductus venous
most O2 even blood skips liver (hepato, 80%) > vena cava > right artery
foramen (hole) ovale
bypasses right ventricle & pulmonary
How? pushes blood into left atrium
skipping lungs > bad after birth
ductus arteriosus
what happens if some blood gets into right ventricle?
opening b/t pulmonary artery and aorta
order
placenta > umbilical vein > ductus venosus > oval foramen > ductus arteriosus > femoral arteries > iliac legs
atrioventircular (AV) valves
between atrium & ventricles
right AV (tricuspid) & left AV (bicuspid)
atria contract
high pressure pushes AV valves open & blood flows into ventricles high to low
ventricle contracts
high pressure pushes AV valves shut
s1 souund lub
blood pushes semilunar open
chordae tendinae
heartstrings
attached to valves > stop valve prolapse & regurgitation into atria
stabilizes valves >
prolapse
regurgitation
open backward
semilunars
exits w/ 3 flaps
pulmonary (stops regurg to RV) & aortic valve (stops regurg to LV)
ventricles relax
pressure drops in them = pulmonary & aortic valve close
sound S2 dup
atria contract
pulmonary V and aortic V closed
systemic side
left
pulmonary side
right
lungs regurgitate
left
body regurg
right