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what are hormones ?
Hormones are primary massagers. They travel in the blood and release by glands. They act on target cells.
what are the 2 types of hormones ?
steroids hormones or non-steroids hormones.
example of Steroids hormones
Steroids hormones E.g. Oestrogen & testosterone are structurally based on and similar to cholesterol.
example of Non- Steroids hormones
proteins.
The Adrenal gland
where is the adrenal gland placed ?
The Adrenal gland located on top of the kidney.
what are the 2 areas of the adrenal gland
2 areas of the adrenal gland; adrenal cortex – adrenal medulla
what does the adrenal cortex do ?
The cortex releases the hormone cortisol
what does the adrenal medulla do ?
The medulla releases the hormone adrenaline (ST flight or fight)
what is the functions of Cortisol (glucocorticoid) ?
Controls metabolism of carbohydrates, fats and proteins in the liver.
Released in the response or low BGL. Blood glucose
Stimulates glycogenolysis. Splitting of glycogen to release glucose.
what is the functions of Mineralocorticoids ?
E.g. aldosterone
Release from the adrenal cortex.
Helps to control Na+ and K+ concentrations in the blood.
Acts as cells of the DCT to increase absorption of Na+ and decrease absorption of K+.
In turn, this contributes to maintain blood pressure.
what is the functions of Adrenaline
Release from the adrenal medulla.
Polar molecules made from the amino acids' tyrosine.
Travels easily in the blood and acts on many cell types.
Target cells express a receptor glycoprotein on the cell surface and a response a generated via a second messenger pathway.
what are the actions of adrenaline ?
Increase heart rate.
Increase stroke volume of the heart.
Dilate smooth muscle in bronchioles.
Dilate pupils.
Converts glycogen to glucose (glycogenolysis)
Causes hair erector muscle to contract (hair stands up)
what is a secondary messenger ? and its functions
Cyclic AMP (cAMP)
Adrenaline is a polar non steroid hormone.
Target cells express glycoprotein receptors on the cell surface membrane.
Effects are induced in the cell using a second messenger molecule.