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hemolytic anemia in pregnant woman results from ___________ produced in response to maternal-fetal blood group incompatibility
IgG Ab
hydrops fetalis occurs when htc and Hb drops to
15%
5g/dl
result of hydrops fetalis is anemia and extravasation of fluid where?
peritoneal cavity, pleural cavity, pericardium
fetus with hydrops is born with what?
hemolytic anemia
hypoxia
acidosis
intrauterine death
US signs of hydrops fetalis
increased liver v., thickened placenta, cardiomegaly
signs of anemia - increased fetal blood velocity
fluid accumulation
echo-doppler sign in hydrops fetalis baby
centralization of circulation (from anemia)
_______is the only invasive dg procedure that ensures fetal blood type, assesses anemia and can provide intraurerine therapy to hydrops fetalis baby
cordocentesis
when can you do cordocentesis to dg hydrops fetalis
18-19w
how to screen a pregnant woman with history of hydrops fetalis baby
chordocentesis as early as possible in future pregnancies + in utero transfusion
prophylaxis of isoimmunization for hydrops fetalis
first trimester screning - maternal blood type, Rh
anti D atc screening (indirect coombs)