Vet Med Pharmaceutical Drugs

Apomorphine

• Used in dogs to induce vomiting

• Effects cannot be reversed

• GI drug

• Opioid

Xylazine

• Used in cats to induce vomiting

• Given by injection

• Yohimbine is the reversal agent

• Can also be a sedative and mild analgesic

Hydromorphone (Dilaudid)

• Rarely used as an emetic

• Has a sedative side effect

• Opioid

Acepromazine

• Tranquilizer

• Antiemetic

Chlorpromazine (Thorazine)

• Tranquilizer

• Antiemetic

Atropine

• Antiemetic

• Anticholinergic

• Dilate pupils, treatment of arrhythmias

• Blocks vagus nerve

Aminopentamide (Centrine)

• Antiemetic

• Anticholinergic

• Blocks vagus nerve

Darbazine

• Antiemetic

• Anticholinergic

• Blocks vagus nerve

Metoclopramide (Reglan)

• Antiemetic

• May cause excitement or hyperactivity in cats

Ondansetron (Zofran)

• Antiemetic

• Given orally or IV

Cisapride (Propulsid)

• Antiemetic

• Used for canine megaesophagus

• Promotility agent for GI tract

• Used for feline megacolon, constipation, and hairballs

Cimetidine (Tagamet)

• Systemic antacid (decreases stomach acid production)

Ranitidine (Zantac)

• Systemic antacid (decreases stomach acid production)

Famotidine (Pepcid)

• Systemic antacid (decreases stomach acid production)

Sucralfate (Carafate)

• Antiulcer

• Forms sticky paste that adheres to ulcer

• Gastroprotectant

• May impair absorption of some PO medications

Omeprazole (GastroGard, Prilosec OTC)

• Treats and prevents GI ulcers

• Given PO

Misoprostol (Cytotec)

• Used to prevent gastric ulcers

• Decreases acid secretion

• Increases stomach mucosa production

Bismuth Subsalicylate (Pepto-Bismol)

• Coats intestinal mucosa

• Protects from enterotoxins

• Decreases inflammation

• Blocks prostaglandin formation