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Fibrocartilage
Thick bundles of collagen fibers arranged in parallel
Chondrocytes
Lacks a perichondrium
Stains pink or blue
Function:
Shock absorption
Resists compression and tension
Provides structural support in high-stress areas.
Likely Look-Alike:
Dense regular connective tissue

Elastic Cartilage
Elastic fibers form a dense, branching network throughout the matrix.
Perichondrium is present
Stains darkly with elastic stains
Function:
Provides flexibility and shape retention
Supports soft tissues while allowing bending and stretching.
Likely Look-Alike:
Hyaline cartilage

Adipose Tissue
Large, empty-looking cells
Nucleus is pushed to the periphery of the cell.
Minimal extracellular matrix (cells are closely packed).
Stains pink or clear in H&E sections.
Energy storage
Insulation
Hormone production
Cushioning
Likely Look-Alike:
Simple squamous epithelium

Areolar Tissue
Loosely arranged fibers
Fibroblasts are the primary cell type.
Gel-like ground substance fills the space between fibers.
Vascularized
Stains pink and purple in H&E sections.
Supports and binds other tissues
Allows diffusion of nutrients and waste
Immune defense (contains macrophages and mast cells).
Likely Look-Alike:
Dense irregular connective tissue:

Hyaline Cartilage
Glassy, smooth matrix with no visible fibers
Chondrocytes are located in lacunae
Perichondrium is present
Stains pink or purple in H&E sections.
Provides smooth surfaces for joint movement
Supports soft tissues (e.g., nose, trachea, ribs).
Template for bone growth (in fetal development).
Likely Look-Alike:
Elastic cartilage

Dense Regular Connective Tissue
Parallel bundles of collagen fibers arranged in a single direction.
Fibroblasts are scattered between the fibers.
Minimal ground substance (appears densely packed).
Poorly vascularized (heals slowly).
Stains pink in H&E sections.
Provides strong attachment (e.g., tendons, ligaments).
Resists tension in one direction (e.g., muscle to bone).
Likely Look-Alike:
Fibrocartilage