Mechanisms of Localization

Tc Sodium pertechnetate brain survival study mechanism of localization

passive diffusion due to disrupted blood brain barrier

Tc Sodium pertechnetate thyroid imaging mechanism of localization

active transport

Tc Sodiium pertechnetate meckels scan mechanism of localization

secretion

Tc HDP and Tc MDP mecahnism of localization

Chemisorption

Tc DTPA renal mechanism of localization

filtration

Tc DTPA lung mechanism of localization

compartmental

Tc DTPA brain survival mechanism of localization

passive diffusion due to disrupted blood brain barrier

Tc MAA mechanism of localization

capillary blockage

Tc Sulfur colloid filtered mechanism of localization

mechanical, follows lymph drainage

Tc sulfur colloid liver spleen scan mechanism of localization

phagocytosis by the RES

Tc sulfur colloid GES mechanism of localization

compartmental

Tc mebrofenin mechanism of localization

(hepatocyte uptake) secretion and compartmental

Tc mertiatide (MAG-3) mechanism of localization

secretion (tubular)

Tc pyrophosphate mechanism of localization

chemical adsorption to microcalcifications

Tc sestamibi mechanism of localization

simple (passive) diffusion

Tc tetrofosmin mechanism of localization

simple (passive) diffusion

Tc succimer (DMSA) mechanism of localization

active transport

Tc exametazime (HMPAO) mechanism of localization

simple diffusion; lipophilic crosses the blood brain barrier

Tc bicisate (ECD) mechanism of localization

simple diffusion; lipophilic crosses the blood brain barrier

Tc RBCs mechanism of localization

compartmental

heat damaged Tc RBCs mechanism of localization

splenic sequestration

Tc HMPAO tagged WBCs mechanism of localization

cellular migration

Tc tilmanocept mechanism of localization

receptor binding

I-123 mechanism of localization

active transport

I-123 MIBG mechanism of localization

receptor binding

I-123 ioflupane mechanism of localization

receptor binding

Ga-67 mechanism of localization

receptor binding

Tl-201 mechanism of localization

active transport

In-111 WBCs mechanism of localization

cellular migration

In-111 DTPA mechanism of localization

compartmental

In-111 pentetreotide mechanism of localization

receptor binding

I-131 mechanism of localization

active transport

Xe-133 mechanism of localization

compartmental

F-18 FDG mechanism of localization

facilitated diffusion

F-18 sodium fluoride mechanism of localization

ion exchange

F-18 fluciclovine mechanism of localization

active transport

Cu-64 dotatate mechanism of localization

receptor binding

Ga-68 mechanism of localization

receptor binding

Ga-68 dotatoc mechanism of localization

receptor binding

Ga-68 gozetotide mechanism of localization

receptor binding

F-18 piflufolastat mechanism of localization

receptor binding

F-18 fluoroestradiol mechanism of localization

receptor binding

F-18 florbetaben, F-18 florbetapir, F-18 flutemetamol mechanism of localizatin

receptor binding

F-18 flortaucipir mechanism of localization

receptor binding

F-18 fluorodopa mechanism of localization

receptor binding

Rb-82 mechanism of localization

active transport

N-13 ammonia mechanism of localization

passive diffusion due to disrupted blood brain barrier

I-131 mechanism of localization

active transport

Lu-177 dotatate mechanism of localization

receptor binding to somatostatin receptors

Lu-177vipivotide tetraxetan mechanism of localization

receptor binding to PSMA receptors

Ra-223 dichloride mechanism of localization

ion exchange

Sr-89 chloride mechanism of localization

ion exchange

Y-90 microspheres mechanism of localization

arterial trapping