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What does antidepressants do?
Affect levels of neurotransmitters like serotonin
What does SSRIs do?
It increases levels of serotonin at the synapse by preventing reuptake of serotonin
For instance Fluoxetine
What did Soomro’s clinical trial find about effectiveness of SSRIs?
SSRIs more effective than placebo in 17 trials
Symptoms reduced for 70% of people taking SSRIs
Why is the use of a drug trial a strength?
They are well controlled experiments which use random allocation, so we can be confident about cause and effect of the drug causing the improvements
What are some side effects of SSRIs that make it an inappropriate treatment?
-weight gain
-low sex drive
-dry mouth
What are some ways that SSRIs are appropriate?
-drugs are easy to administer and don’t require time off work like CBT
-cheap for NHS than paying for a clinical psychologist, more effective for economy as help people return to work quicker