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Nutrition
The study of how food nourishes the body and influences health, involving food consumption, digestion, absorption, storage, factors influencing eating patterns, recommended food amounts, food safety, and the global food supply.
Macronutrients
Nutrients required in large amounts for energy provision, including carbohydrates, fats, and proteins.
Micronutrients
Nutrients needed in smaller amounts, such as vitamins and minerals.
Caloric content of macronutrients
Carbohydrates and proteins provide 4 calories per gram, while lipids provide 9 calories per gram.
Dietary Reference Intakes (DRIs)
Guidelines for nutrient intake, including EAR, RDA, AI, and UL.
Acceptable Macronutrient Distribution Ranges (AMDR)
Recommended range of macronutrient intake associated with reduced chronic disease risk.
Estimated Energy Requirement (EER)
Predicted average energy intake to maintain balance, considering factors like age, gender, and physical activity level.
Scientific method
Involves observation, hypothesis, experiment, data analysis, and hypothesis acceptance or modification.
Nutrigenomics
Study of how food influences gene expression and interacts with genes, the environment, and nutrition.
Probiotics and Prebiotics
Probiotics are foods with beneficial microorganisms, while prebiotics are non-digestible food ingredients supporting probiotic growth.
Phytochemicals
Plant compounds with health benefits, protecting against diseases, reducing inflammation, and enhancing immune function.
Thermic Effect of Food (TEF)
Energy expended during the digestion, absorption, transport, metabolism, and storage of nutrients.
Macronutrients with highest TEF
Protein and carbohydrates have a higher TEF compared to fat.
Genetic inheritance
Factors like height, weight, body shape, and metabolic rate inherited from parents.
Thrifty gene theory
Proposes genes causing individuals to be energetically thrifty, leading to weight gain during times of low energy expenditure.
Metabolic factors influencing weight
Include low metabolic rate, physical inactivity, low sympathetic nervous system activity, and low thyroid hormone levels.
Satiety factors
PYY, serotonin, CCK, increased blood glucose levels, stomach expansion, and nutrient absorption from the small intestine increase satiety.
Red flags for diet hype
Rapid weight loss, claims of specific food combinations that "burn fat," rigid menus, and use of supplements.
Strategies for healthy weight loss
Setting realistic goals, consuming smaller portions of nutrient-dense foods, increasing low-energy-dense foods, and regular physical activity.
Mindful eating tips
Focus on eating, savor each bite, recruit all senses, pause between bites, and try moments of silence.
Obesity
Excess body fat adversely affecting health, characterized by visceral fat accumulation and metabolic abnormalities.
Complications of obesity
Metabolic syndrome, hypertension, type 2 diabetes, and cardiovascular disease are common complications.
Carbohydrate digestion
Begins in the mouth with salivary amylase, continues in the small intestine with pancreatic amylase and other enzymes.
Hormones regulating blood glucose
Insulin lowers blood glucose levels, while glucagon raises them.
Glycemic index
Measures a food's impact on blood glucose levels, with low GI foods causing mild glucose fluctuations.
Fiber importance
Reduces the risk of various diseases, enhances weight loss, and aids in digestive health.
Essential fatty acids
Linoleic acid (Omega-6) and alpha-linolenic acid (Omega-3) must be obtained from the diet and are precursors to important regulatory compounds in the body.
Atherosclerosis
Accumulation of cholesterol-rich plaque on artery walls leading to arteriosclerosis
Modifiable risk factors for CVD
Overweight, inactivity, smoking, type 2 diabetes, inflammation, abnormal blood lipids, high blood pressure
Blood lipids differences:
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Largest lipoprotein, formed in the gut after a meal
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Formed in the liver, 80%; intestine, 20%
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"Bad cholesterol," formed from VLDL in the blood
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"Good cholesterol," synthesized in the liver
Protein building blocks
Amino acids joined by peptide bonds
Essential vs
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Must be obtained from food
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Can be made by the body
Protein turnover
Continuous synthesis and degradation of proteins
Protein structure levels
Primary, secondary, tertiary, quaternary
Denaturation
Loss of protein shape due to heat, pH, heavy metals
Incomplete vs
Incomplete lack essential amino acids; complete contain all essential amino acids
Mutual vs
Mutual combines incomplete proteins; complementary supply all essential amino acids together
Functions of proteins
Structure, enzymes, hormones, immunity, energy source, nutrient transport, nerve function, blood clotting, wound healing
Fluid compartments in the body
Intracellular fluid (ICF) and extracellular fluid (ECF)
Solvent vs
Solvent dissolves substances; solute is dissolved materials
Osmosis
Movement of solvent molecules through a membrane to equalize solute concentration
Electrolytes for nerve cells
Sodium and potassium
Thirst mechanism
Controlled by the hypothalamus; stimulated by salt increase, blood volume reduction, dry mouth
ADH function
Regulates water balance, blood pressure, urine concentration, thirst
Functions of sodium
Fluid balance, blood pressure, nerve impulse transmission, nutrient transport
Hypernatremia
High blood sodium, can result in high blood volume, edema, high blood pressure
Hyponatremia
Low blood sodium, can result from vomiting, diarrhea, sweating
Hyperkalemia
High blood potassium level, can occur in patients with kidney disease, can alter normal heart rhythm, may result in a heart attack
Hypokalemia
Low blood potassium levels, can occur in patients with kidney disease or diabetic acidosis, can occur when taking certain diuretic medications, symptoms include confusion, loss of appetite, muscle weakness
Phosphorus functions
Fluid balance, bone formation, energy formation, found in ATP, DNA, RNA, regulates biochemical pathways by activating or deactivating enzymes
High blood phosphorus
Can occur in kidney disease, after taking too many vitamin D supplements, or over-consuming phosphorus-containing antacids, causes muscle spasms and convulsions
Heat Cramps
Painful muscle cramps, usually in the abdomen, arms, or legs, develop during vigorous activity sessions in the heat, important to stop activity immediately, cool down, and rest
Heat Exhaustion
Typically occurs from vigorous activity in heat, symptoms include cramps, weakness, vomiting, dizziness, elevated blood pressure & pulse, must be treated promptly to prevent heat stroke
Heat Stroke
Occurs if the body’s temperature regulation mechanisms fail, symptoms include rapid pulse, hot dry skin, high body temp, weakness, can be fatal in extreme cases
Moderate alcohol consumption benefits
May reduce the risk of heart disease, associated with lower risk of blood clots and dementia, may increase appetite
Alcohol absorption
In the stomach and small intestine, some metabolized by alcohol dehydrogenase in the stomach, about 80% absorbed in the small intestine
Alcohol dehydrogenase
Enzyme that metabolizes alcohol, converts ethanol to acetaldehyde, alcohol circulates in the blood until fully metabolized
Phosphorus in Bone Health
Combines with calcium in hydroxyapatite crystals
Functions of Magnesium
Component of bone, regulates bone status, influences hydroxyapatite formation, cofactor for enzymes, role in ATP, DNA, protein synthesis, supports vit. D metabolism, heart health, blood clotting
Functions of Fluoride
Found in teeth and bones, enhances tooth mineralization, reverses tooth demineralization, inhibits acid-producing bacteria
Fluorosis
Excessive fluoride consumption increases protein content on teeth enamel
Functions of Vitamin D
Regulates calcium, phosphorus absorption, blood calcium, stimulates osteoclasts, necessary for bone calcification
Vitamin D Synthesis
Skin (UV light to provitamin D), Liver (provitamin D to calcidiol), Kidneys (calcidiol to calcitriol)
Factors Affecting Vitamin D Synthesis
Latitude, time of year, time of day, skin color, age, obesity, sun protection
Osteoporosis
Low bone mass, increased fracture risk
Components of Physical Fitness
Cardiorespiratory, Musculoskeletal fitness, Flexibility, Body composition
Overload Principle
To improve fitness, place extra physical demand on the body
FITT Principle
Frequency, Intensity, Time, Type
ATP Fuel Duration
ATP in muscle fuels activity for 1-3 seconds
Aerobic vs
Aerobic requires oxygen, Anaerobic can occur without oxygen
Glycolysis
Breakdown of glucose for energy production
Carbohydrate Breakdown Duration
Supports activities lasting 30 seconds to 3 minutes
Ergogenic Aids
Anabolic steroids, Androstenedione, DHEA, Creatine, Caffeine, Ephedrine, Carnitine, Chromium
Body Image
Perception, feelings, and assessment of one's body
Disordered Eating vs
Atypical eating behaviors vs. severe eating disorders
Anorexia Nervosa
Self-starvation, low body weight, nutrient deficiency, health risks
Bulimia Nervosa
Binge eating, purging behaviors, health risks
Anorexia Athletica
Athletes with eating disorder characteristics
Female Athlete Triad
Low energy availability, menstrual dysfunction, low bone density
Embryonic Stage
Week 3 to week 8 of development
Teratogens
Drugs, alcohol, viruses, during embryonic stage
Placenta
Nutrient exchange, hormone production, no blood mixing
Low Birth Weight Risks
Infections, learning disabilities, impaired development
Folate Importance
Critical in the first 28 days for neural tube development
Maternal Smoking Effects
Exposes fetus to toxins, reduces blood flow, risks of complications
Pregnancy Nutrition Concerns
Morning sickness, cravings, GER, constipation, gestational diabetes, preeclampsia
Toddler Supplements
Some benefit due to erratic eating behaviors
Encouraging Nutritious Choices
Combat peer pressure, model healthy eating, involve children in meal prep
Growth in Adolescence
Driven by puberty, hormonal changes
Skeletal Growth Stop
Closure of epiphyseal plates
Adolescent Nutrition Concerns
Peer influence, sporadic eating, lack of fruits and vegetables
Acne in Teenage Years
Hormonal changes, stress, genetics, hygiene
Physiological Changes in Aging
Sensory decline, GI changes, body composition changes
Geriatric Weight Loss Causes
Dementia, drugs, dysphagia, dysgeusia, depression, disease