bone cells

osteogenic cells

give rise to most other bone cells

osteogenic cells are found in

the osteogenic layer of periosteum and endosteum and can multiply continually

some osteogenic cells

differentiate into osteoblasts

osteoblasts

bone forming cells

osteoblasts secrete

protein mixture (osteoid) that hardens and becomes the bony matrix

osteoblasts are

non mitotic- formed from osteogenic cells in response to mechanical stress

osteocytes

mature bone cells

osteocytes are

osteoblasts that have trapped themselves in the matrix they secreted, reside in spaces called lacunae which are connected by canaliculi

canaliculi

allow osteocytes to connect and communicate via gap junctions

osteocytes function to

maintain bony matrix

osteocytes also

play a role in sensing stressors and influence bone remodeling

osteoclasts

bone dissolving

osteoclasts perform

osteolysis (opposite of osteogenesis)

osteoclasts DO NOT

develop from osteogenic cells

osteoclasts formed from

the fusion of stem cells

osteoclasts ruffled border

present in resorption bays, involved in bone remodeling and blood calcium homeostasis