SDPA- Neoplasms

what is a sign of Leser-Trélat

sudden appearance of multiple SKs (commonly associated with gastric adenocarcinoma)

What is the hyperpigmented papules on face of dark-skinned individuals called

Dermatosis papulosa nigra

What is Leser-Trélat a sign of

gastric adenocarcinoma

white keratotic papules (typically less than 4 mm in diameter) on the lower extremities of lighter-skinned individuals is called what

stucco keratosis

What is the autosomal dominant disorder characterized by numerous flat, wart-like papules on the dorsal aspects of the hands and feet.

Acrokeratosis Verruciformis

Acrokeratosis verruciformis is related to what other disease

Darier disease

ATP2A2 mutation can lead to what two diseases

Darier disease

Acrokeratosis verruciformis

a red papule or plaque with a shiny surface, usually located on the lower extremity, and it may have a peripheral collarette of scale

Clear cell acanthoma

what is this

large cell acanthoma

acanthoma originates where

epidermal prickle cell layer, stratum spinosum

How to manage a large cell acanthoma

cryotherapy

close monitoring and histopath eval due to the uncertain behavior of these tumors

Unclear if it will behave benignly or malginantly

Large plaque arising in infancy or childhood on distal extremities, several centimeters in diameter

this is what

porokeratosis of Mibelli

Multiple pink-brown papules and plaques with peripheral scale that arises in sun-exposed areas like forearms and shins

may have autosomal dominant inheritance

Disseminated superficial actinic porokeratosis (DSAP)

streaks along the lines of Blaschko

Arises early in life and is associated with higher risk of SCC

linear porokeratosis

why is linear porokeratosis important

arises early in life and can be associated with risk of SCC

these papules on palms and soles, typically appearing during adolescence or adulthood

punctate porokeratosis

Palmoplantar papules with involvement of trunk, extremities, and sometimes mucous membrane with Onset during childhood or adolescence, what kind of porokeratosis

porokeratosis palmaris et plantaris et disseminata

porokeratotic plaques and papules within the gluteal cleft or folds is called what

porokeratosis ptychotropica

how do you treat DSAP

Topical treatments, such as retinoids, imiquimod, fluorouracil, and 2% lovastatin (with or without 2% cholesterol), are options, though recurrence is common.

Inflammatory linear verrucous epidermal nevus looks like what other condition

psoriasis

a type of epidermal nevus. It is characterized by a linear plaque composed of grouped comedones.

nevus comdionicus

what type of nevus is associated with a mutation in fibroblast growth factor receptor 2 (FGFR2)

nevus comidonicus

what is Flegel disease

hyperkeratosis lenticularis perstans

keratotic papules on the lower legs

hyperkeratosis lenticularis perstans is also known as what

Flegel disease

______ appears as a pink to brown papule or plaque. It may mimic non-melanoma skin cancer (NMSC), such as BCC, and typically occurs on actinically damaged skin

lichen planus-like keratosis

scaly to verrucous hyperpigmented plaques. It has a reticular (net-like) appearance at the periphery

Favors neck, chest and submammary areas

Confluent and Reticulated Papillomatosis (of Gougerot and Carteaud)

how do you treat CARP

oral tetracyclines

what is CARP

scaly to verrucous hyperpigmented plaques. It has a reticular (net-like) appearance at the periphery

pilomatricoma

trichofolliculoma

fibrofolliculoma

If you see this, what syndrome would you might think it is associated with

Birt-Hogg-Dubé syndrome

Tumor of the follicular infundibulum

what does the tumor of follicular infundibulum overlap with

superficial basal cell carcinoma

__________ is a pink-red to skin-colored papule or nodule most commonly found on the face and less frequently on the upper trunk. It is associated with Brooke-Spiegler syndrome (BSS), a rare familial autosomal dominant condition caused by a defect in the CYLD gene.

Trichoepithelioma

what to tell a patient about risk of metastasis from invasive SCC

2-4% risk of nodal mets depending on area:

lip, ear, genitalia

tumor diameter >2cm

poor diff

invasion beyond subcu fat

perineural invasion