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Flashcards based on key concepts from the lecture on Behavioral Epigenetics and Reinforcement Strategies.
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Epigenetics
The study of how genes and environment interact to influence gene expression.
Phenotype
The actual expression of an individual’s genes, influenced by environmental factors.
Exposome
The totality of environmental exposures an individual experiences throughout their life.
Examples:
Stressful home vs. loving home
Clean air vs. pollution
Childhood trauma vs. support
Poverty vs. safe community
Positive Reinforcer
A consequence that strengthens behavior by its added presence.
Negative Reinforcer
A consequence that strengthens behavior by being subtracted from the situation.
Behavioral Epigenetics
The study of how gene expression impacts behavior, particularly in social and health-related contexts.
Health Disparities
Health differences closely linked with social, economic, and environmental disadvantage.
Reinforcement
A consequence that increases the likelihood of a behavior being repeated.
Self-Reinforcement
The practice of reinforcing one's own behavior to encourage continued action.
Gene-Environment Interaction
The complex interplay between genetics and environmental factors in determining individual traits and behaviors.
Epigeneteics
the gene enviroment interactionthat affects gene expression and can influence behavior.
Epigenetic mechanism
chemical processes that influence the ability of DNA to give instructors(how genes are expressed) and influence whether phenotype associated with gene variants become manifest physically or clinically.
Enviroment influences these mechanism
physical enviroment,the social enviroment ,the behavioral enviroment,psychological enviroment,vultural factors -this factors interact with a person’s genetic makeup to result in health outcomes
IMPLICATIONS FOR HEALTH
PROMOTION INTERVENTIONS
3 chategories : 1.prevention of epigenetic risk
conditions 2.reversing
epigenetic changes 3.mitigation
prevention of epigenetic risk
conditions
One category of intervention is prevention of epigenetic risk
conditions in the first place—improving access to prenatal
and early childhood care, reducing poverty, and reducing
unhealthy environmental exposures
(Example: prenatal care, reduce poverty)
reversing
epigenetic changes,
A second category, for which there are few models, would be
to target some health promotion programs at reversing
epigenetic changes, insofar as that is possible. This might
include parent interventions, family and community violence
intervention.
(Example: therapy, violence prevention)
mitigation
A possible third category could be called mitigation—for
example, increasing social support or other factors that buffer
the effects of negative epigenetic changes.
(Example: increase social support)
EPIGENETIC PROCESSES –
COPYING THE GENES (OR NOT)
Genes are composed of segments of DNA and associated proteins.
For a gene to be copied and expressed, its DNA segment has to be
“read” during the developmental process. This is done by RNA,
which binds to the DNA and copies the genetic sequence in order
to produce the proteins for its expression.
EPIGENETIC PROCESSES –
COPYING THE GENES (OR NOT)
BUT…various processes can affect whether or not a genetic
sequence is read or not. These processes include
– DNA methylation
– Histone modification
EPIGENETIC PROCESSES –
COPYING THE GENES (OR NOT)
Leaving the technicalities aside, these processes (and others) are
influenced by environmental factors. SO, THE KEY IS THAT
GENETIC EXPRESSION IS AFFECTED BY THE
ENVIRONMENT…NATURE AND NURTURE TOGETHER
What Epigenetics Really Means
Your DNA is like a big library of books.
Every book is a gene.
But not every book gets read.
Some remain on the shelf.
What decides whether a book is read?
👉 The environment
What Epigenetics Really Means
You are born with genes (genotype)
But your life experiences decide which genes turn ON or OFF (phenotype)
So — genes are not your destiny.
Your environment shapes them.