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The Intravenous Route
Advantages
Rapid acting
Achieves therapeutic blood levels
Reduce impact of irritating medications
Disadvantages
Rapid acting
Drug/infusion begins to act immediately
Risk of fluid volume overload
Possible Complications
Medication incompatibilities can occur when two or more medications or IV fluid are administered.
Physical incompatibilities change the appearance of the medication.
Chemical incompatibilities change the potency of one of the medications.
Thrombophlebitis - vascular irritation of the veins.
Extravasation of certain medications can result in tissue damage around the IV site.
Rapid adverse reaction.
Speed shock. A systemic reaction to a substance rapidly injected into the blood; happens if medication is given too fast.
Different Modes of IV Medication
Large volume infusions (continuous or intermittent)
Medication mixed into a large volume IV container (500mL or 1000mL).
Bolus injection (IV push)
Concentrated dose of medication manually pushed directly into vein.
Small volume.
Volume-controlled infusions
Piggyback
Small IV bag (25-250mL) attached to primary IV line.
Pump: Push ‘Piggyback’ setting.
Gravity: Bag placed higher than primary line.
When secondary line is infusing, primary line “on hold”.
Tandem (concurrent)
Small IV bag (25-250mL) attached to primary IV line.
Pump: Push ‘Concurrent’ Setting.
Gravity line: IV bags placed at same height.
Both lines infuse into patient at same time.
Volume-control set
50-150mLs
Used to deliver a small amount of medication.
Connected to primary IV line.
Mini-infuser pump
Meds mixed in a syringe.
Infused over 10-150 min.
Attached to primary line o saline lock.
Special Considerations
C - Compatibility
A - Allergies
T - Tubing/Time
S - Site
P - Pump (Programmed Precisely, Personality, Pumping, Plugged in)
R - Rights
R - Release
R - Return and Reassess
IV Compatibility
Is the medication you are giving compatible with the IV fluids the drug is being mixed with?
Calculating Rates of Infusion
Infuse the entire mini-bag content when administering medications via the secondary line.
Your volume to be infused (VTBI) will vary based on how much volume of med you add to the mini-bag.
Total mL ordered / Number of hrs to run = rate in mL/hr
Managing Patients with Infections
What populations are at risk?
Chemotherapy/radiation
Diabetes
Corticosteroid therapy
HIV/AIDS
On meds that suppress the immune system
Transplant recipients
Malnutrition
Recognizing Cues - Symptoms
Purulent drainage, change in normal drainage
Fever, chills, malaise
Enlarged lymph nodes
GI nausea/upset/diarrhea
Analyzing Cues - Culture and Sensitivity
Culture samples: urine, blood, stool, drainage
Take before antibiotics
Reconstitution
Many meds are created in a powdered form because they are unstable when stored in liquid form.
These powdered meds need to be mixed with a liquid(i.e. NS or SW) to create a liquid preparation for administration.
Solute – substance to be dissolved or diluted (powder)
Solvent/Diluent– substance (liquid) that dissolves another substance to prepare a solution.
Solution – the resulting mixture of a solute plus a solvent (liquid)
Identify on the manufacturer directions:
The type of diluent to use
The amount of diluent to add
The length of time the med is stable for after reconstituted
The strength or concentration of the medication after reconstitution.
Types of reconstituted solutions:
Single strength - 1 set of directions on the label.
Multiple strength - multiple sets of directions on the label.