2. Databases
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9 Terms
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GenBank
* the oldest continuously running database containing nucleic acid sequence data.
* supplies source material for R, a database that contains natural (wild-type) sequences. • ) is a database that . • To read a GenBank file it is helpful to know gene structure organization and alternative splicing of transcripts.
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* supplies source material for R, a database that contains natural (wild-type) sequences. • ) is a database that . • To read a GenBank file it is helpful to know gene structure organization and alternative splicing of transcripts.
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Reference Sequence (RefSeq)
contains only wild-type sequences of DNA, RNA, and proteins
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Protein Knowledge Database (UniProtKB)
a well-annotated database focused on the protein products of the genes found in GenBank
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RefSeq database
information is derived from GenBank records (secondary database b/c it contains information from a primary database)
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RefSeq database
more than one record can be generated from a single stretch of DNA
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RefSeq database
shows whether more than one RNA molecule can be transcribed from a single DNA region
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Entrez
a search engine hosted by NCBI that allows searching several databases simultaneously for certain subjects
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Medline
a database that contains science literature and is often accessed through the PubMed portal
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Online Median Inheritance of Man (OMIM)
database that describes human genes and disorders associated with genes.to search for human diseases