Psychology - Chapter 5: OCD

Rapoport (1898)

Diagnostic criteria: Case study of Charles, with obsessive thoughts of something sticky on his skin and has to be washed off.

Szechman et al., (1998)

Biochem explanation - Dopamine - Increase dopamine in rats → rats show repetitive behaviors reflecting compulsive behaviors in OCD

Pittenger and Bloch (2014)

Biochem explanation: Serotonin - Anti-depressants (SSRI) are better at treating OCD than ones that does not focus on alternating serotonin level

Leckman et al., (1994)

Biochem explanation: OT dysfunction - Found OT dysfunction as a cause of OCD after assessing cerebral spinal fluid

Monzani et al., (2014)

Genetical influence: MZ > DZ twins in concordance rate for OCD (52% > 21%)

Ozaki et al., (2003)

Genetical Mutation: SERT gene mutations in 2 unrelated families with OCD

Mattheisen et al.,(2015)

Genes contribution: PTPRD, SLITRK3

Rachman (1977)

Cognitive explanation: Claims faulty reasoning leads to obsessive thoughts

Soomro et al. (2008)

Biochem treatment: Meta-analysis of 17 studies claiming SSRI is more effective than placebos

Lehmkuhl et al., (2008)

Exposure Response prevention: Case study with 12 year old Jason, with both ASD and OCD (Contamination, checking, counting, excessive washing)

Lovell et al., (2006)

Cognitive behavioral therapy: Comparing CBT face to face vs phone delivered, with results suggesting both treatment delivery are effective