Part 4: Org and func of glutamatergic system

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Last updated 6:10 PM on 6/22/26
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8 Terms

1
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4 functions of glutamate

  • synaptic plasticity

  • Learning and memory

  • Cell death in disease

  • Development of disorder

2
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What are the three types of ionotropic glutamate receptors

  1. AMPA

  2. Kainate

  3. NMDA

3
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What activity do AMPA receptors help with

Locomotor

4
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What ionotropic glu receptor requires a co-agonist and opens two receptors

NDMA

5
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What ionotropic glu receptors function in learning and memory

AMPA and NMDA

6
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What ionotropic glu receports function with synaptic plasticity

NMDA, they release glutamate which can strengthen the synapse

7
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How many Metabotropic glu receptors are there and what are the function of these

8

  • motor control

  • Pain relief

  • Locomotive

  • Some inhibit glutamate

8
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What is the excitotxoicity hypothesis

Increasing glutamate levels can be toxic to nerve cells

The idea is that prolonged depolarization of receptive neurons can lead to damage or death