Analgesic and Anti-inflammatory

Aspirin

NSAID that irreversibly inhibits COX-1 & 2

Ibuprofen

NSAID that inhibits COX-1 & 2

Ketorolac

NSAID that reversibly inhibits COX-1 & 2

Celecoxib

only selective COX-2 inhibitor for inflammation & pain

Acetaminophen

reduces prostaglandins to reduce fever & pain

prednisone

glucocorticoid reduces inflammation in RA

sulfasalazine

DMARD suppresses immune cell activity

etanercept

DMARD neutralize TNF-a

rituximab

DMARD destroys B-cells to reduce autoantibodies

abatacept

DMARD reduces T-cell proliferation

colchicine

reduces inflammation in acute gout

allopurinol

decreases uric acid production for chronic gout

probenecid

inhibits reabsorption of uric acid for chronic gout

pegloticase

converts uric acid to allantoin to be excreted by kidneys for chronic gout

sumatriptan

serotonin receptor agonist to constrict cranial blood vessels for migraines

ergotamine

2nd line for migraines

baclofen

acts in spinal cord muscle relaxer for spasticity

cyclobenaprine

acts in brainstem muscle relaxer for spasticity

morphine

opioid acts on mu & kappa for MI

fentanyl

opioid acts on mu & kappa for surgery & intubation

codeine

opioid acts on mu & kappa for cough suppression

naloxone

opioid antagonist

tramadol

weak mu activity and blocks norepi and serotonin reuptake

methadone

mu receptor mimics opioid without high

suboxone

mu agonist & kappa antagonist for opioid withdrawal