Suspensions Lab

Suspension

A mixture of solid particles dispersed throughout a liquid.

True

T/F: The drug concentration is higher than its solubility in the liquid

False

T/F: Suspensions do not need to be shaken before use

Slow settle

For the particles to be consistent, what must happen to allow consistent dose measurement?

Sediment

After suspension settles is known as what process?

14-90 days

Compounded suspensions typically have a beyond use date (BUD) of how many days

glycerin, propylene glycol

Used to Levigate/Wet the powders with a viscous water-soluble liquid & prevent clumping

Conical graduate

The following item is used to transfer the compounded liquid. What is it?

Easier mixing

A conical graduate is used for what reason?

methylcellulose 1500 2%

In the first suspension, which one of the ingredients is used as a water-soluble polymer to decrease suspension settling rate

Glycerin

In Suspension 1, which of the following is used as a water-soluble solvent for levigating the powders

Zinc oxide, calamine

In the 1st suspension, which of the following will be put in the mortar to mix?

glycerin

In the first suspension, what is being measured out in the syringe first to put into the mortar?

Thick paste with no dry particles

In Suspension 1, after triturating with the glycerin, what should the product look like?

methylcellulose solution (3mL portions)

In the first suspension, what should be added in portions to triturate well?

Purified water (20mL)

In the 1st suspension, after the solution, what should added while triturating to mix?

conical graduate

Mixtures will be transferred from the mortar & pestle → what?

purified water

In suspension 1, after transferring the mixture, the mortar with additional amount of _____ to add to the conical graduate

exceed 60 mL for the suspension

What matters is that the mixture does not …

Stirring & transferring to bottle to label

What is the final step in suspension 1 example?

multiply the purified water amount by acetaminophen

To figure out how much acetaminophen is needed, you must …

Acemtaminophen

In Suspension 2, which of the following will be weighed out and placed in the mortar?

methylcellulose 2%

After placing the powder in the mortar, 30 mL of ____ is being measured in 50 mL graduate

methylcellulose solution

To triturate we;; & create a thick paste in portion, what is being added