Blood Bank Week 1 Review Questions

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28 Terms

1
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Indicate which immunoglobulin class (IgG or IgM) best represents the property.

Warm Reactive

IgG

2
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Indicate which immunoglobulin class (IgG or IgM) best represents the property.

Detectible at immediate spin

IgM

3
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Indicate which immunoglobulin class (IgG or IgM) best represents the property.

Small enough to cross the placenta, potentially causing HDFN

IgG

4
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Indicate which immunoglobulin class (IgG or IgM) best represents the property.

Best at fixing compliment

IgM

5
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Indicate which immunoglobulin class (IgG or IgM) best represents the property.

First one seen in the primary immune response

IgM

6
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Which protein in the compliment system is identifiable on the red cell surface after compliment has been activated?

A. C9

B. C5

C. C3b

D. IgM

C. C3b

7
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What percent of offspring are predicted to be blood type A from this pairing:

1 parent = BO

1 parent = AA

A. 100%

B. 50%

C. 25%

D. 0%

B. 50%

8
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An antigen is expressed on the outside surface of the red cell. Which statement is true regarding the gene for the blood group?

A. The patient has 2 homozygous genes for the antigen

B. The gene for the antigen is dominantly expressed

C. The patient's gene codes for the allele of the specific antigen

D. The gene is heterozygous for the allele

C. The patient's gene codes for the allele of the specific antigen

9
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For the following red cell chemical properties, indicate whether they are increased or decreased during the storage lesion.

Glucose

Decreased

10
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For the following red cell chemical properties, indicate whether they are increased or decreased during the storage lesion.

ATP

Decreased

11
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For the following red cell chemical properties, indicate whether they are increased or decreased during the storage lesion.

Lactic Acid

Increased

12
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For the following red cell chemical properties, indicate whether they are increased or decreased during the storage lesion.

pH

Decreased

13
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For the following red cell chemical properties, indicate whether they are increased or decreased during the storage lesion.

2,3 DPG

Decreased

14
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For the following red cell chemical properties, indicate whether they are increased or decreased during the storage lesion.

Plasma Potassium

Increased

15
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True or False: additive solutions increase the shelf life of red cell products by requiring the removal of plasma from the red cells

False

16
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Which grade would you give to an agglutinate that has a single large chunk and several smaller chunks in the tube?

A. 4+

B. 3+

C. 2+

D. 1+

E. 0

B. 3+

17
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Given the following reaction results, is the antigen present or absent?

Positive Control with Anti-C: 3+

Negative Control with Anti-C: 0

Patient Cells with Anti-C: 2+

A. Present

B. Absent

C. Inconclusive

A. Present

18
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Which of the following occurs during storage of RBCs? Select all that apply.

A. pH decreases

B. 2,3-DPG increases

C. ATP increases

D. Plasma K+ increases

A. pH decreases

D. Plasma K+ increases

19
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Which of the following immunoglobulins is most efficient at causing direct hemmaglutination?

A. IgG

B. IgM

C. IgA

D. IgE

IgM

20
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A nurse just called to add on a cross-match to a pre-transfusion specimen you worked on 4 days ago. What is the most appropriate course of action?

A. Check to see if volume is sufficient in original sample to complete the work-up

B. Perform compatibility testing on original specimen

C. Indicate to the nurse that a new specimen needs to be collected for pre-transfusion testing

D. Repeat type and screen testing on original sample to see if the patient has made any antibodies after transfusion

C. Indicate to the nurse that a new specimen needs to be collected for pre-transfusion testing

21
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Patient plasma with donor red cells produced an agglutination reaction of 1+. How do you interpret this?

A. The reaction is weak, the patient can probably tolerate the donor cells

B. The donor blood is compatible with patient plasma

C. The donor plasma is compatible with patient blood

D. The donor blood is incompatible with patient plasma

D. The donor blood is incompatible with patient plasma

22
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Which reagent has antigen in it (select all that apply)?

- Check Cell

- A1 Cell

- Anti-B

- Anti-IgG

- Anti-A

- Anti-A,B

- B Cell

Check Cell, A1 Cell, B Cell

23
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For tube testing, which reagent is added first?

A. Cell

B. Antibody

B. Antibody

24
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Match the agglutination description with the grade: 0

A. Agglutinates remove easily in large chunks as cell button is shaken

B. All cells stick together in one solid chunk

C. Cells appear to remove from the cell button as smoke

D. Many small agglutinates in a clear background

E. As cell button is shaken, agglutinates appear to come off as cookie bites

C. Cells appear to remove from the cell button as smoke

25
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Match the agglutination description with the grade: 1+

A. Agglutinates remove easily in large chunks as cell button is shaken

B. All cells stick together in one solid chunk

C. Cells appear to remove from the cell button as smoke

D. Many small agglutinates in a clear background

E. As cell button is shaken, agglutinates appear to come off as cookie bites

E. As cell button is shaken, agglutinates appear to come off as cookie bites

26
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Match the agglutination description with the grade: 2+

A. Agglutinates remove easily in large chunks as cell button is shaken

B. All cells stick together in one solid chunk

C. Cells appear to remove from the cell button as smoke

D. Many small agglutinates in a clear background

E. As cell button is shaken, agglutinates appear to come off as cookie bites

D. Many small agglutinates in a clear background

27
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Match the agglutination description with the grade: 3+

A. Agglutinates remove easily in large chunks as cell button is shaken

B. All cells stick together in one solid chunk

C. Cells appear to remove from the cell button as smoke

D. Many small agglutinates in a clear background

E. As cell button is shaken, agglutinates appear to come off as cookie bites

A. Agglutinates remove easily in large chunks as cell button is shaken

28
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Match the agglutination description with the grade: 4+

A. Agglutinates remove easily in large chunks as cell button is shaken

B. All cells stick together in one solid chunk

C. Cells appear to remove from the cell button as smoke

D. Many small agglutinates in a clear background

E. As cell button is shaken, agglutinates appear to come off as cookie bites

B. All cells stick together in one solid chunk