Neuro2 L4 Local Anesthetics

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6 Terms

1
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Ester local anesthetics

metabolism: plasma pseudocholinesterases

onset: slow

duration: short

PABA = allergy

2
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Amide local anesthetic

metabolized: liver

onset: fast

duration: long

3
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local anesthetic

voltage gated Na channel block => prevent dopol and conduction

sensitivity: C > A-delta > A alpha

blockade: sensory > pain

4
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cocaine

only local anesthetic to cause vasoconstriction

5
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bupivacaine

cardiovascular toxicity- manage w/ intralipid IV lipid emulsion

6
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Prilocaine and Benzocaine and Tetracaine

Methemoglobinemia