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22 Terms

1
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What are the three main branches of modern genetics?

Transmission genetics, evolutionary genetics, and molecular genetics.

2
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What is the basic unit of heredity?

Gene.

3
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Define genotype.

The genetic makeup of an organism.

4
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Define phenotype.

The set of observable characteristics of an individual resulting from the interaction of its genotype with the environment.

5
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What does PCR stand for?

Polymerase Chain Reaction.

6
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What is Mendel's Law of Segregation?

During gamete formation, the two alleles for a trait separate, so each gamete receives only one allele.

7
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What is a test cross used for?

To determine the genotype of an individual with an unknown genotype by crossing it with a homozygous recessive individual.

8
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What is the primary difference between hypothesis testing and discovery-based science?

Hypothesis testing starts with a specific question or potential answer, while discovery-based science aims to explore and discover without a preconceived hypothesis.

9
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What is epistasis?

The interaction of genes that are not alleles, in particular the suppression of the effect of one gene by another.

10
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What is a gamete?

A sex cell; in plants and animals, an egg or sperm.

11
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What is the human genome size?

3.3 billion base pairs.

12
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What is the role of the centromere in cell division?

It is the region of a chromatid that contains the kinetochore, where spindle fibers attach during mitosis.

13
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What are homologous chromosomes?

Chromosomes that are similar in morphology and genetic constitution, containing the same genes arranged in the same order.

14
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What is a pedigree?

A family tree used to trace the inheritance of traits in humans and some animals.

15
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What is meant by the term 'autosome'?

A chromosome that is not a sex chromosome.

16
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Define dominant allele.

A variant of a gene that expresses itself more strongly than other versions of the gene.

17
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What is pleiotropy?

A single gene affecting multiple traits.

18
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What is binary fission?

A type of asexual reproduction where a cell splits into two identical daughter cells.

19
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What is the general size of typical eukaryotic cells?

10-100 microns in diameter.

20
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What occurs during crossing-over?

The breaking and rejoining of homologous (nonsister) chromatids during early meiotic prophase I that results in an exchange of genetic material.

21
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What is the process of meiosis?

A process in which a diploid cell undergoes two successive nuclear divisions, potentially producing four haploid nuclei.

22
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Name a common characteristic shared by model organisms in genetics research.

Quick generation time.